Cellular biology and pharmacology of the placenta : techniques and applications : [derived from the Tenth Rochester Trophoblast Conference, held Oct. 8-10, 1985, in Rochester, New York>

Front Matter ....Pages i-xiii Front Matter ....Pages 1-1 Biochemical and Immunological Aspects of the Human Trophoblast Cell Surface (Paul D. Webb, Nicholas Hole, P. Jeremy McLaughlin, Peter L. Stern, Peter M. Johnson)....Pages 3-15 Identification of Distinct Receptors for Native and Acetylated-Low-Density Lipoprotein in Human Placental Microvilli (Eliane Alsat, Francoise Mondon, André Malassiné, Regis Rebourcet, Sonia Goldstein, Lise Cedard)....Pages 17-27 Influence of the Lipid Environment on Insulin Binding to Placental Membranes from Normal and Diabetic Mothers (Gernot Desoye, Peter A. M. Weiss)....Pages 29-43 Renin Release from Human Chorionic Trophoblasts in Vitro: The Role of Cyclic Amp and Protein Kinase C (Alan M. Poisner, Promila Agrawal, Roselle Poisner)....Pages 45-60 Amnionic Association with Chorion and Prostaglandin E2 Production before and after Labor (John A. McCoshen)....Pages 61-69 Arachidonic Acid Metabolism in the Human Placenta (Matthew P. Rose, Murdoch G. Elder, Leslie Myatt)....Pages 71-83 Does Human Trophoblast Affect Decidual Cell Function During Gestation? (Ljiljana Vićovac, Mirjana Vučković, Olga Genbačev)....Pages 85-93 S-Adenosyl-L-Methionine Mediated Enzymatic Methylations in the Plasma Membranes of the Human Trophoblast (Stanley L. Barnwell, B. V. Rama Sastry)....Pages 95-120 Front Matter ....Pages 121-121 Recent Advances in Understanding the Immunobiology of Gestational Trophoblastic Disease (Ross S. Berkowitz, Donald P. Goldstein, Deborah J. Anderson)....Pages 123-137 O-Glycosylation of Proteins in the Normal and Neoplastic Trophoblast (Laurence A. Cole)....Pages 139-148 Placental Production of Immunoregulatory Factors: Trophoblast is a Source of Interleukin-1 (Elliott K. Main, Julie Strizki, Peter Schochet)....Pages 149-160 Regulation of Maternal Anti-Paternal Immune Responses in Vitro by Uterine Macrophages (Gary W. Wood, Ossama W. Tawfik, Joan S. Hunt)....Pages 161-171 Characterization of Maternal Trophoblast Lymphocyte Cross-Reactive (TLX) Immunity (Donald S. Torry, John A. McIntyre, W. Page Faulk, Peter R. McConnachie)....Pages 173-185 The Association of Mixed Lymphocyte Reaction (MLR) Blocking Factors and Maternal Antipaternal Leukocytotoxic Antibodies with Pregnancy Outcome in Women with Recurrent Abortions Immunized with Paternal or Third Party Leukocytes (Alan E. Beer, James F. Quebbeman, A. Enrico Semprini, Zhu Xiaoyu)....Pages 187-197 Monoclonal Antibodies to Equine Trophoblast (Douglas F. Antczak, J. Clare Poleman, Laura M. Stenzler, Stephen G. Volsen, W. R. Allen)....Pages 199-214 The Expression of Epithelial Antigens by Trophoblasts and Tumor Cells Using Monoclonal Antibodies to Human Amnion (GB3 and GB5) (Chang-Jing G. Yeh, Bae-Li Hsi)....Pages 215-222 Studies of C1q Deposits in the Human Placenta Using Monoclonal Antibodies to Human Extra-Embryonic Tissues (Bae-Li Hsi, Chang-Jing G. Yeh)....Pages 223-231 Front Matter ....Pages 233-233 P-450 Cytochromes in the Human Placenta: Oxidations of Xenobiotics and Endogenous Steroids (Mont R. Juchau, Moses J. Namkung, Allan E. Rettie)....Pages 235-263 Human Placental Cytochrome P-450: Microsomal Preparation and Purification (Charles W. Fisher, John J. Moore)....Pages 265-277 Partial Purification of the Opioid Receptor from Human Placenta (Mahmoud S. Ahmed, Anna G. Cavinato)....Pages 279-287 Regional and Differential Sensitivity of Umbilico-Placental Vasculature to 5-Hydroxytryptamine, Nicotine, and Ethyl Alcohol (B. V. Rama Sastry, L. K. Owens)....Pages 289-304 Placental Distribution and the Effect of Antihypertensive Drugs on Monoamine Oxidase and Cathechol-o-Methyl Transferase Activity at Term (Eytan R. Barnea, A. H. De Cherney, Frederick Naftolin)....Pages 305-314 Maternofetal Potential Differences: Studies Using the In Vitro Pig Placenta (B. S. Ward, W. M. O. Moore, C. P. Sibley, J. D. Glazier, R. D. H. Boyd)....Pages 315-327 Human Placental Ca2+-ATPases: Targets for Organochlorine Pesticides? (Arun P. Kulkarni, Kimberly A. Treinen, Lorelle L. Bestervelt)....Pages 329-342 The Placenta as a Model for Toxicity Screening of New Molecules (Rebecca Beaconsfield, Bojana Cemerikic, Olga Genbacev, Vojin Sulovic)....Pages 343-356 The Pharmacokinetics of Cadmium in the Dually Perfused Human Placenta (Patrick J. Wier, Richard K. Miller)....Pages 357-366 Characterization of Magnetic Resonance Parameters in the Pregnant Uterus (Peter J. Thomford, Janet Jordan, Teresita Angtuaco, H. Howard Cockrill, Donald R. Mattison)....Pages 367-393 The Actions of Prostaglandins and the Interactions of Angiotensin II in the Isolated Perfused Human Placental Cotyledon (David G. Glance, Murdoch G. Elder, Leslie Myatt)....Pages 395-404 Front Matter ....Pages 405-405 Differentiaton of Human Cytotrophoblast into Syncytiotrophoblast in Culture (Harvey J. Kliman, Michael A. Feinman, Jerome F. Strauss III)....Pages 407-421 Isolation and Characterization of Human Cytotrophoblast Cells (Susan Daniels-McQueen, Alexander Krichevsky, Irving Boime)....Pages 423-445 Characterization of Isolated Cells in Primary Culture from Human term Placenta by Electron Microscopy and Immunohistochemistry (Juliet O. Lobo, Francis L. Bellino, Alan Siegel)....Pages 447-460 Trophoblast Cell Culture (Y. W. Charles Loke, Robert O. Hussa)....Pages 461-464 Front Matter ....Pages 465-465 Placental Steroid Dehydrogenases: Assessment with a Nonhuman Primate in Situ Placental Perfusion Model (William Slikker Jr., John R. Bailey, George W. Lipe, Zelda Althaus, Julian E. A. Leakey)....Pages 467-479 Nucleotide Interconversion and Breakdown in the Dually Perfused Guinea Pig Placenta (Bernard van Kreel, J. P. van Dijk, A. M. C. M. Pijnenburg)....Pages 481-499 Uptake of Ascorbic Acid and Its Oxidized Products in the Isolated Guinea Pig Placenta (Heinz-Peter Leichtweiss, Belisario Lisbôa, Christiane Steinborn)....Pages 501-514 Criteria for Standardizing and Judging Viability Placental Perfusions in Animals (Bruce J. Kelman, Bernard K. van Kreel)....Pages 515-522 Front Matter ....Pages 523-523 Transfer of Antipyrine, H2O, L-Glucose and α-Aminoisobutyric Acid Across the in Vitro Perfused Human Placental Lobe (Henning Schneider, Mariette Proegler, Reto Duft)....Pages 525-533 The Modulation of Glucose Transfer Across the Human Placenta by Intervillous Flow Rates: An In Vitro Perfusion Study (Nicholas P. Illsley, S. Hall, T. E. Stacey)....Pages 535-544 Long Term Human Placental Lobule Perfusion — An Ultrastructural Study (P. Anthony di Sant’Agnese, Karen L. de Mesy Jensen, Patrick J. Wier, Debabrata Maulik, Richard K. Miller)....Pages 545-555 Are There Membrane-Lined Channels through the Trophoblast? A Study with Lanthanum Hydroxide (Peter Kaufmann, Hobe Schroeder, Heinz-Peter Leichtweiss, Elke Winterhager)....Pages 557-571 Transfer of Horseradish Peroxidase Across the Human Placental Cotyledon Perfused in Vitro (Mario Sideri, Elena Zannoni, Jean-Claude Challier)....Pages 573-584 Interrelationships of Perfusion Parameters in the Dual-Perfused Human Placental Cotyledon (Randy B. Howard, Janet Levy, Tomokazu Hosokawa, M. Helen Maguire)....Pages 585-596 In Vitro Perfusion of Human Placenta (Henning Schneider, Joseph Dancis)....Pages 597-605 Back Matter ....Pages 607-625