Cellular and Molecular Control of Neuronal Migration (Advances in Experimental Medicine and Biology (800))

__Cellular and Molecular Control of Neuronal Migration__ provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches.__Cellular and Molecular Control of Neuronal Migration__ also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians. Cellular and Molecular Control of Neuronal Migration provides an up-to-date collection of reviews on the molecular and cellular principles of neuronal migration in the mammalian brain. Over the last decades a rich catalogue of signaling molecules controlling neuronal migration has been compiled, and within this book an international panel of experts provides up-to-date discussions of the state of knowledge how these distinct signaling pathways regulate various aspects of neuronal migration. This book introduces the reader to the latest discoveries and concepts of neuronal migration enabled through the application of most sophisticated methods and cutting edge experimental approaches. Cellular and Molecular Control of Neuronal Migration also provides an update on the underlying cellular and molecular basis of neurodevelopmental migration disorders in human patients for all interested neuroscientists and clinicians. Front Matter....Pages i-x Molecular Pathways Controlling the Sequential Steps of Cortical Projection Neuron Migration....Pages 1-24 The Dynamics of Neuronal Migration....Pages 25-36 The Impact of JNK on Neuronal Migration....Pages 37-57 Novel Functions of Core Cell Cycle Regulators in Neuronal Migration....Pages 59-74 Microtubules and Neurodevelopmental Disease: The Movers and the Makers....Pages 75-96 Mark/Par-1 Marking the Polarity of Migrating Neurons....Pages 97-111 The PAR Polarity Complex and Cerebellar Granule Neuron Migration....Pages 113-131 Spinal Motor Neuron Migration and the Significance of Topographic Organization in the Nervous System....Pages 133-148 Extracellular Signals Controlling Neuroblast Migration in the Postnatal Brain....Pages 149-180 Back Matter....Pages 181-186