Cell Physiology : Source Book

A multi-authored and comprehensive text, **Cell Physiology Source Book** enables graduate students in various biological sub-disciplines to gain a thorough understanding of cell physiology. It begins with a reviewof the physical chemistry of solutions, protein structure, and membrane structure, and ends with an Appendix featuring reviews of electricity, electrochemistry, and cable properties of cells. In between, this book is loaded with information on membrane potentials, cell metabolism, signal transduction, transport physiology and pumps, membrane excitability and ion channels, synaptic transmission, sensory transduction, muscle contraction, excitation-contraction coupling, bioluminescence, photosynthesis, andplant cell physiology.This exhaustive work provides graduate students with detailed and authoritative coverage of nearly all aspects of cell physiology. Such broad coverage of this field within a single source makes for a unique text.Chapters written in a clear, concise, and didactic style, and appropriate reviews of basic physics and chemistry are among the many distinguishing features of this monumental treatise. Comprehensive source-book of cell physiologyAuthoritative and multi-authored by leading experts in the fieldUnique features include broad coverage and review of relevant physics, chemistry, and metabolismClear, concise, and didacticIncludes reviews of physical chemistry of solutions, protein structure, membrane structure, electrochemistry, and electricityTopic covered include plant cell physiology, photosynthesis, bioluminescence, effects of pressure, cilia, and flagellaeDetailed treatise on ion channels and their regulation Content: Front Matter , Page iii Copyright , Page iv Dedication , Page v Contributors , Pages xi-xii Foreword , Page xiii Preface , Page xv , Nicholas Sperelakis 1 - Biophysical Chemistry of Cellular Electrolytes , Pages 3-17 , Jeffrey C. Freedman 2 - The Physiological Structure and Function of Proteins , Pages 18-35 , Matthew R. Pincus 3 - Lateral Lipid Domains and Membrane Function , Pages 36-44 , Friedhelm Schroeder, W. Gibson Wood 4 - Ultrastructure of Cells , Pages 45-60 , Donald G. Ferguson 5 - Diffusion and Permeability , Pages 61-66 , Nicholas Sperelakis 6 - Origin of Resting Membrane Potentials , Pages 67-90 , Nicholas Sperelakis 7 - Gibbs–Donnan Equilibrium Potentials , Pages 91-95 , Nicholas Sperelakis 8 - Energy Production and Metabolism , Pages 96-116 , Michael A. Lieberman, Richard G. Sleight 9 - Signal Transduction , Pages 117-127 , Richard G. Sleight, Michael A. Ueberman 10 - Calcium as an Intracellular Second Messenger: Mediation by Calcium Binding Proteins , Pages 128-136 , John R. Dedman, Mania A. Kaetzel 11 - Transport of Ions and Nonelectrolytes , Pages 139-147 , John Cuppoletti 12 - The Sodium Pump , Pages 148-155 , Earl Taylor Wallick 13 - Ca 2+ -ATPases , Pages 156-165 , Istvan Edes, Evangelia G. Kranias 14 - Na-Ca Exchange Currents , Pages 166-179 , John H.B. Bridge 15 - Osmosis and the Regulation of Cell Volume , Pages 180-211 , Clive M. Baumgarten, Joseph J. Feher 16 - Intracellular pH Regulation , Pages 212-229 , Robert W. Putnam 17 - Polarity of Cell Membranes , Pages 230-242 , Robert W. Putnam 18 - Cable Properties and Propagation of Action Potentials , Pages 245-254 , Nicholas Sperelakis 19 - Electrogenesis of Membrane Excitability , Pages 255-278 , Nicholas Sperelakis 20 - Patch-Clamp Techniques and Analysis , Pages 279-292 , Raymund Y.K. Pun, Harold Lecar 21 - Structure and Mechanism of Voltage-Gated Ion Channels , Pages 293-314 , Simon Rock Levinson 22 - Ion Channels in Nonexcitable Cells , Pages 315-329 , Bernd Nilius 23 - Ion Channels in Sperm , Pages 330-339 , A. Lievano, A. Darszon 24 - Biology of Gap Junctions , Pages 340-350 , William J. Larsen, E. Michael Hendrix 25 - Biophysics of the Nuclear Envelope , Pages 351-366 , Louis J. DeFelice, Michele Mazzanti 26 - Regulation of Ion Channels by Phosphorylation , Pages 367-377 , Nicholas Sperelakis 27 - Ion Channels That Are Directly Regulated by G Proteins , Pages 378-385 , Atsuko Yatani 28 - Ion Channels as Targets for Toxins , Pages 389-403 , Kenneth Blumenthal 29 - Ion Channels as Targets for Drugs , Pages 404-412 , R. Kent Hermsmeyer 30 - Ion Channels as Targets for Genetic Disease , Pages 413-427 , S.H. Bryant 31 - Ligand-Gated Ion Channels , Pages 431-441 , Gary L. Westbrook 32 - Synaptic Transmission , Pages 442-463 , Janusz B. Suszkiw 33 - Excitation-Secretion Coupling , Pages 464-482 , Nicole Gallo-Payet, Marcel Daniel Payet 34 - Stretch-Sensitive Ion Channels , Pages 483-489 , Catherine E. Morris 35 - Mechanoreceptor and Sonoreceptor Transduction , Pages 490-494 , M.M. Behbehani 36 - Cyclic Nucleotide-Gated Ion Channels , Pages 495-505 , Anita L. Zimmerman 37 - Visual Transduction , Pages 506-513 , Anita L. Zimmerman 38 - Olfactory/Taste Receptor Transduction , Pages 514-522 , S. Roper 39 - Stimulus Transduction in Metabolic Sensor Cells , Pages 523-536 , Stanley Misler 40 - Skeletal Muscle Action Potentials , Pages 539-555 , Nicholas Sperelakis 41 - Cardiac Action Potential , Pages 556-565 , Gordon M. Vahler 42 - Smooth Muscle Action Potentials , Pages 566-579 , R. Kent Hermsmeyer 43 - Ca 2+ Release from Sarcoplasmic Reticulum in Muscle , Pages 580-591 , Gerhard Meissner 44 - Contractility of Muscles , Pages 592-610 , R.J. Paul 45 - Amoeboid Movement, Cilia, and Flagella , Pages 611-637 , Edna S. Kaneshiro 46 - Spasmonemes/Centrin-Based Contraction and Bacterial Flagella , Pages 638-654 , Edna S. Kaneshiro 47 - Physiological Effects of Pressure on Cell Function , Pages 655-662 , Thomas K. Akers 48 - Bioluminescence , Pages 665-681 , J. Woodland Hastings 49 - Photosynthesis , Pages 682-696 , Darrell Fleischman 50 - Plant Cell Physiology , Pages 697-711 , Richard G. Stout Appendix - Review of Electricity and Cable Properties , Pages 713-725 Index , Pages 727-738 A multi-authored and comprehensive text, Cell Physiology Source Book enables graduate students in various biological sub-disciplines to gain a thorough understanding of cell physiology. It begins with a reviewof the physical chemistry of solutions, protein structure, and membrane structure, and ends with an Appendix featuring reviews of electricity, electrochemistry, and cable properties of cells. In between, this book is loaded with information on membrane potentials, cell metabolism, signal transduction, transport physiology and pumps, membrane excitability and ion channels, synaptic transmission, sensory transduction, muscle contraction, excitation-contraction coupling, bioluminescence, photosynthesis, andplant cell physiology.
This exhaustive work provides graduate students with detailed and authoritative coverage of nearly all aspects of cell physiology. Such broad coverage of this field within a single source makes for a unique text.
Chapters written in a clear, concise, and didactic style, and appropriate reviews of basic physics and chemistry are among the many distinguishing features of this monumental treatise.

Comprehensive source-book of cell physiology
Authoritative and multi-authored by leading experts in the field
Unique features include broad coverage and review of relevant physics, chemistry, and metabolism
Clear, concise, and didactic
Includes reviews of physical chemistry of solutions, protein structure, membrane structure, electrochemistry, and electricity
Topic covered include plant cell physiology, photosynthesis, bioluminescence, effects of pressure, cilia, and flagellae
Detailed treatise on ion channels and their regulation Cell Physiology Source Book provides a comprehensive discussion of physiology and biophysics at the cellular level. The book is organized into seven sections covering biophysical chemistry, electrochemistry, metabolism, second messengers, and ultrastructure (Section I); transport physiology, pumps, and exchangers (Section II); membrane excitability and ion channels (Section III); ion channels as targets for toxins, drugs, and genetic diseases (Section IV); synaptic transmission and sensory transduction (Section V); muscle and other contractile systems (Section VI); and bioluminescence and photosynthesis (Section VII). This text was written for graduate and advanced undergraduate students in the life sciences, including those taking courses in cell physiology, cell biophysics, and cell biology. Selected parts of this book can be used for courses in neurobiology, electrobiology, electrophysiology, secretory biology, biological transport, and muscle contraction. Students majoring in engineering, biomedical engineering, physics, and chemistry may use the book to understand the living state of matter. The text can serve as a reference tool for s postdoctoral scholars and faculty engaged in biological research. Medical, dental, and allied health students can also use this book to complement other textbooks in medical/mammalian physiology. This comprehensive source-book of cell physiology and membrane biophysics covers the workings of animal and plant cells, including: the structure and function of cell membranes; ion transport; origin of membrane potentials; excitability; structure and function of ion channels and their regulation; synaptic transmission; sensory transduction; muscle contraction, cilia, and flagellae; excitation-contraction coupling; bioluminescence; photosynthesis; metabolism; and signal transduction. The book also contains chemistry and physics reviews, allowing graduate students to gain a full appreciation of how cells work, send signals internally, transduce signals from the environment, and communicate with other cells This reference covers the workings of animal and plant cells, including: the structure and function of cell membranes; ion transport; origin of membrane potentials; excitability; structure and function of ion channels and their regulation; synaptic transmission; and sensory transduction.