Cell interactions in differentiation [recurso electrónico] Sixth Sigrid Jusélius Foundation Symposium, Helsinki, Finland, August 1976

Cell Interactions in Differentiation is a collection of papers presented at the Sixth Sigrid Jusélius Foundation Symposium held in Helsinki, Finland, in August 1976. Contributors discuss cell interactions during differentiation, particularly referring to the problem of embryonic induction. They also consider how a cell becomes adjusted to the synchronized development of an entire multicellular organism, so as to express its genetic information at a strictly controlled time and place. This volume is organized into five sections encompassing 30 chapters and begins with an overview of embryonic cells and their two fundamental properties. Cells are not necessarily predetermined and can be experimentally diverted from their normal developmental pathway, and those within an embryonic organism require extrinsic messages to express their developmental capacities. The next chapters focus on early determinative events in embryogenesis, touching on topics such as the genetic aspects of cell type determination, interactions between embryonic cells during the early development of the mouse, and the differentiation of teratocarcinoma stem cells in vitro. The reader is then introduced to positional information and morphogenetic signals; the biological''specificity''of morphogenetic tissue interactions; and the molecular mechanisms underlying cell contact interactions. The remaining chapters explore some of the most important conceptual and methodological approaches to the problems of cell-cell recognition and the integration of cells into multicellular systems. This book will be of interest to scientists and investigators in developmental biology and related fields. Content: ORGANIZING COMMITTEE , Page ii Front Matter , Page iii Copyright , Page iv LIST OF PARTICIPANTS , Page v PREFACE , Pages vii-viii , M.K.-J., L.S., L.W. OPENING REMARKS , Pages ix-x , NILS OKER-BLOM INTRODUCTION , Page xi Early Determinative Events in Embryogenesis: An Introduction , Pages 3-4 , ANNE MCLAREN Analysis of a Cytoplasmic Determinant in an Insect Egg , Pages 5-21 , KLAUS KALTHOFF Genetics of Cell Type Determination , Pages 23-43 , ROBERT BRIGGS Interactions between Embryonic Cells during the Early Development of the Mouse , Pages 45-57 , C.F. GRAHAM, S.J. KELLY The Differentiation of Teratocarcinoma Stem Cells in vitro: Parallels to Normal Embryogenesis , Pages 59-75 , GAIL R. MARTIN Positional Information and Morphogenetic Signals: An Introduction , Pages 79-87 , L. WOLPERT Compartments in the Development of Drosophila: a Progress Report , Pages 89-95 , PETER A. LAWRENCE Positional Signalling and Nerve Cell Specificity , Pages 97-110 , R. KEVIN HUNT Organizing Principles for Anatomical Patterns and for Selective Nerve Connections in the Developing Amphibian Brain , Pages 111-124 , JONATHAN COOKE Regulation of Proximo-distal Pattern Formation in the Developing Limb , Pages 125-140 , MADELEINE KIENY Embryonic Induction: A Historical Note , Pages 143-144 , SULO TOIVONEN Morphogenetic Tissue Interactions: An Introduction , Pages 145-151 , LAURI SAXÉN Tissue Interactions in Amniote Skin Development , Pages 153-169 , PHILIPPE SENGEL, DANIELLE DHOUAILLY The Differentiation of the Ganglioblasts of the Autonomic Nervous System Studied in Chimeric Avian Embryos , Pages 171-190 , NICOLE LE DOUARIN Tissue Interactions in Tooth Development in vitro , Pages 191-207 , IRMA THESLEFF Epigenetic Regulation of Enamel Protein Synthesis during Epithelial-Mesenchymal Interactions , Pages 209-226 , HAROLD C. SLAVKIN, GARY N. TRUMP, STEVEN SCHONFELD, ANNA BROWNELL, NINO SORGENTE, VICTOR LEE-OWN Studies on Primary Embryonic Induction , Pages 227-247 , D. TARIN Kidney Tubule Induction: Physical and Chemical Interference , Pages 249-261 , STIG NORDLING, PETER EKBLOM, EERO LEHTONEN, LAURI SAXÉN, JORMA WARTIOVAARA Stimulation of Chondrogenic Differentiation with Extracellular Matrix Components: An Analysis using Scanning Electron Microscopy , Pages 263-272 , JAMES W. LASH, ELIZABETH BELSKY, N.S. VASAN Molecular Mechanisms of Cell Contact Interactions: An Introduction , Pages 275-277 , LEONARD WEISS Some Biophysical Aspects of Cell Contact, Detachment and Movement , Pages 279-289 , LEONARD WEISS Some Chemical Bases for Biological Specificity as Exemplified by Hapten-Antibody Interactions , Pages 291-309 , ALLAN L. GROSSBERG Interactions of Fibronectin, a Cell-Type Specific Surface-Associated Glycoprotein , Pages 311-323 , A. VAHERI, D. MOSHER, J. WARTIOVAARA, J. KESKI-OJA, M. KURKINEN, S. STENMAN Gap Junctions and Cell Contacts , Pages 325-338 , NORTON B. GILULA The Molecular Basis of the Mesenchymal-Epithelial Interactions in Pancreatic Development , Pages 339-350 , RAYMOND L. PICTET, WILLIAM J. RUTTER Cell Recognition: An Introduction , Pages 353-355 , A.A. MOSCONA Mechanisms of Cell—Cell Recognition: Some Comparisons between Lower Organisms and Vertebrates , Pages 357-376 , MAX M. BURGER Periodic Cyclic-AMP Signals and Membrane Differentiation in Dictyostelium , Pages 377-388 , G. GERISCH, D. MALCHOW, W. ROOS, U. WICK, B. WURSTER Developmental Interactions Studied with Experimental Teratomas derived from Mutants at the T/t Locus in the Mouse , Pages 389-398 , DOROTHEA BENNETT, KAREN ARTZT, TERRY MAGNUSON, MARTHA SPIEGELMAN Self-recognition Phenomenon in Acquired Immunity , Pages 399-408 , O. MÄKELÄ, SAIJA KOSKIMIES SUBJECT INDEX , Pages 409-415