Cell Biology and Translational Medicine, Volume 8 : Stem Cells in Regenerative Medicine

Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the eight volume of a continuing series. Front Matter ....Pages i-viii The Future of Stem Cell Research and its Clinical Translation in Canada: Exploring Questions of Governance and Policy Options (Amy Zarzeczny)....Pages 1-16 Future Cell and Gene Therapy for Osteoarthritis (OA): Potential for Using Mammalian Protein Production Platforms, Irradiated and Transfected Protein Packaging Cell Lines for Over-Production of Therapeutic Proteins and Growth Factors (Ali Mobasheri)....Pages 17-31 The Horizon of Gene Therapy in Modern Medicine: Advances and Challenges (Babak Arjmand, Bagher Larijani, Motahareh Sheikh Hosseini, Moloud Payab, Kambiz Gilany, Parisa Goodarzi et al.)....Pages 33-64 Developments in Artificial Platelet and Erythroid Transfusion Products (Neslihan Meric, Gulen Guney Esken, Merve Uslu, Fatih Kocabas)....Pages 65-87 Advancing Mesenchymal Stem Cell Therapy with CRISPR/Cas9 for Clinical Trial Studies (Ali Golchin, Forough Shams, Farshid Karami)....Pages 89-100 Mesenchymal Stem Cells in Asthma (Tunc Akkoc)....Pages 101-108 Oocyte Aging: The Role of Cellular and Environmental Factors and Impact on Female Fertility (Toka A. Ahmed, Sara M. Ahmed, Zaynab El-Gammal, Shaimaa Shouman, Ashrakat Ahmed, Ragaa Mansour et al.)....Pages 109-123 Targeting Cancer Metabolism and Cell Cycle by Plant-Derived Compounds (Esra Aydemir Çoban, Didem Tecimel, Fikrettin Şahin, Ayşen Aslı Hızlı Deniz)....Pages 125-134 Differentiation Potential of Mesenchymal Stem Cells into Pancreatic β-Cells (Safa Aydin, Derya Sağraç, Fikrettin Şahin)....Pages 135-156 Zooming in across the Skin: A Macro-to-Molecular Panorama (Ayşen Aslı Hızlı Deniz, Ezgi Avşar Abdik, Hüseyin Abdik, Safa Aydın, Fikrettin Şahin, Pakize Neslihan Taşlı)....Pages 157-200 Back Matter ....Pages 201-203 "In this next volume in the Cell Biology and Translational Medicine series, we continue to explore the potential utility of stem cells in regenerative medicine. Chapters in this volume cover advances and challenges in applications of particular stem cell populations in a variety of diseases and conditions, and certain governance and policy issues and options"--Preface