Case Studies in Immunology: Hereditary Angioneurotic Edema : A Clinical Companion

Учебник по иммунологии. One of the most important functions of the adaptive immune system is the production of antibodies. It is estimated that a human being can make more than one million different specific antibodies. This remarkable feat is accomplished through a complex genetic program carried out by B lymphocytes and their precursors in the bone marrow.

Case Studies in Immunology, Sixth Edition, presents major topics of immunology through a selection of clinical cases that reinforce and extend the basic science. The case histories illustrate essential points about the mechanisms of immunity and describe immunological problems seen in the clinic. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. Case Studies in Immunology highlights major common disorders of immunity, including hypersensitivity types I-IV, immune deficiencies, and autoimmune disorders. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the specific disorders. An end-of-case summary, questions, and discussion points conclude each case.

Case Studies in Immunology can be used as a stand-alone book, or as a clinical companion alongside Janeway’s Immunobiology, Eighth Edition. A marginal icon in Janeway’s Immunobiology provides the reader with a link to the relevant Case Study, where the science is applied in a clinical setting.

The book includes a total of 53 cases. The Sixth Edition is extensively revised and updated and includes ten new cases:

• DiGeorge Syndrome
• Hemophagocytic Lymphohistiocytosis
• Chediak-Higashi Syndrome
• Hyper IgE Syndrome
• Ataxia Telangiectasia
• Warts, Hypogammaglobulinemia, Infections, and Myelokathexis (WHIM) Syndrome
• Severe Congenital Neutropenia
• Recurrent Herpes Simplex Encephalitis
• Systemic Onset Juvenile Idiopathic Arthritis
• Crohn’s Disease

Case Studies in Immunology, Fifth Edition, cites major topics of immunology as the background to a selection of real clinical cases that serve to reinforce and extend the basic science. This new edition vividly illustrates the importance of an understanding of immunology in diagnosis and therapy. As well as being a valuable review aid, Case Studies in Immunology introduces in a clinical setting the major common disorders of immunity, including hypersensitivity types I-IV and autoimmune disorders such as lupus and multiple sclerosis. It also describes and explains the consequences of some of the most important immune deficiencies. Each case history is preceded by basic scientific facts essential to understanding the immunology behind the disease or disorder. An end-of-case summary, questions, and discussion points finish each case This book presents case histories to illustrate in a clinical context essential points about the mechanisms of immunity. It includes cases that illustrate both recently discovered genetic immunodeficiencies and some more familiar and common diseases with interesting immunology.