Casarett & Doull's Toxicology: The Basic Science of Poisons, Seventh Edition (Casarett & Doull Toxicology)

The most complete, trusted reference text covering the full span of medical toxicology. A Doody's Core Title Essential Purchase! 'This reference stands alone as the basic text in the field of toxicology. This authoritative reference is written by many distinguished professionals in the field, and offers clear, concise descriptions of the key concepts in toxicology. It is extensive and complete, covering a broad range of topics in sufficient detail. Both as a reference and as an educational tool, this book exceeds its goal of serving as a reference for toxicologists, other scientists, and students of the discipline. 3 Stars' - Doody's Review Service. Long established as the gold standard in the field, "Casarett & Doull's Toxicology" equips you with an unsurpassed understanding of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline. The new seventh edition features is updated throughout and includes many new contributors and new content on chemical terrorism Long Established As The Gold Standard In The Field, Casarett & Doull's Toxicology Equips You With An Unsurpassed Understanding Of Modern Toxicology, Including The Principles, Concepts, Mechanisms, And Modes Of Thought That Are The Foundation Of The Discipline. The New Edition Features Many New Contributors, New Content On Chemical Terrorism, And Is Updated Throughout.--publisher Description. Unit I: General Principles Of Toxicology -- History And Scope Of Toxicology / Michael A. Gallo -- Principles Of Toxicology / David L. Eaton And Steven G. Gilbert -- Mechanisms Of Toxicity / Zoltán Gregus -- Risk Assessment / Elaine M. Faustman And Gilbert S. Omenn -- Unit Ii: Disposition Of Toxicants -- Absorption, Distribution, And Excretion Of Toxicants / Lois D. Lehman-mckeeman -- Biotransformation Of Xenobiotics / Andrew Parkinson And Brian W. Ogilvie -- Toxicokinetics / Danny D. Shen- Unit Iii: Non-organ-directed Toxicity -- Chemical Carcinogens / James E. Klaunig And Lisa M. Kamendulis -- Genetic Toxicology / R. Julian Preston And George R. Hoffmann. Developmental Toxicology / John M. Rogers And Robert J. Kavlock -- Unit Iv: Target Organ Toxicity -- Toxic Responses Of The Blood / John C. Bloom And John T. Brandt -- Toxic Responses Of The Immune System / Norbert E. Kaminski ... [et Al.] -- Toxic Responses Of The Liver / Hartmut Jaeschke -- Toxic Responses Of The Kidney / Rick G. Schnellmann -- Toxic Responses Of The Respiratory System / Hanspeter R. Witschi ... [et Al.] -- Toxic Responses Of The Nervous System / Virginia C. Moser ... [et Al.] -- Toxic Responses Of The Ocular And Visual System / Donald A. Fox And William K. Boyes -- Toxic Responses Of The Heart And Vascular System / Y. James Kang. Toxic Responses Of The Skin / Robert H. Rice And Theodora M. Mauro -- Toxic Responses Of The Reproductive System / Paul M.d. Foster And L. Earl Gray Jr. -- Toxic Responses Of The Endocrine System / Charles C. Capen -- Unit V: Toxic Agents -- Toxic Effects Of Pesticides / Lucio G. Costa -- Toxic Effects Of Metals / Jie Liu, Robert A. Goyer, And Michael P. Waalkes -- Toxic Effects Of Solvents And Vapors / James V. Bruckner, S. Satheesh Anand, And D. Alan Warren -- Health Effects Of Radiation And Radioactive Materials / Naomi H. Harley -- Properties And Toxicities Of Animal Venoms / John B. Watkins, Iii. Toxic Effects Of Plants / Stata Norton -- Unit Vi: Environmental Toxicology -- Air Pollution / Daniel L. Costa -- Ecotoxicology / Richard T. Di Giulio And Michael C. Newman -- Unit Vii: Applications Of Toxicology -- Food Toxicology / Frank N. Kotsonis And George A. Burdock -- Analytic/forensic Toxicology / Alphonse Poklis -- Clinical Toxicology / Louis R. Cantilena Jr. -- Occupational Toxicology / Peter S. Thorne.mode Of Access: World Wide Web. Editor, Curtis D. Klaassen. Includes Bibliographical References And Index. Mode Of Access: World Wide Web. Cover Page......Page 1 Title Page......Page 4 ISBN 0071470514......Page 5 Contents (with page links)......Page 7 Contributors......Page 11 Preface......Page 15 Preface to the First Edition......Page 17 Unit 1 General Principles of Toxicology......Page 21 1 History and Scope of Toxicology......Page 23 2 Principles of Toxicology......Page 31 3 Mechanisms of Toxicity......Page 65 4 Risk Assessment......Page 127 Unit 2 Disposition of Toxicants......Page 149 5 Absorption, Distribution, and Excretion of Toxicants......Page 151 6 Biotransformation of Xenobiotics......Page 181 7 Toxicokinetics......Page 325 Unit 3 Non-Organ-Directed Toxicity......Page 347 8 Chemical Carcinogens......Page 349 9 Genetic Toxicology......Page 401 10 Developmental Toxicology......Page 435 Unit 4 Target Organ Toxicity......Page 473 11 Toxic Responses of the Blood......Page 475 12 Toxic Responses of the Immune System......Page 505 13 Toxic Responses of the Liver......Page 577 14 Toxic Responses of the Kidney......Page 603 15 Toxic Responses of the Respiratory System......Page 629 16 Toxic Responses of the Nervous System......Page 651 17 Toxic Responses of the Ocular and Visual System......Page 685 18 Toxic Responses of the Heart and Vascular System......Page 719 19 Toxic Responses of the Skin......Page 761 20 Toxic Responses of the Reproductive System......Page 783 21 Toxic Responses of the Endocrine System......Page 829 Unit 5 Toxic Agents......Page 903 22 Toxic Effects of Pesticides......Page 905 23 Toxic Effects of Metals......Page 953 24 Toxic Effects of Solvents and Vapors......Page 1003 25 Health Effects of Radiation and Radioactive Materials......Page 1075 26 Properties and Toxicities of Animal Venoms......Page 1105 27 Toxic Effects of Plants......Page 1125 Unit 6 Environmental Toxicology......Page 1139 28 Air Pollution......Page 1141 29 Ecotoxicology......Page 1179 Unit 7 Applications of Toxicology......Page 1211 30 Food Toxicology......Page 1213 31 Analytic/Forensic Toxicology......Page 1259 32 Clinical Toxicology......Page 1279 33 Occupational Toxicology......Page 1295 A......Page 1315 C......Page 1316 D......Page 1318 E......Page 1319 F......Page 1320 H......Page 1321 I......Page 1322 M......Page 1323 N......Page 1324 P......Page 1325 S......Page 1327 T......Page 1328 V......Page 1330 Z......Page 1331 The seventh edition of Casarett and Doull’s Toxicology: The Basic Science of Poisons, as the previous six, is meant to serve primarily as a text for, or an adjunct to, graduate courses in toxicology. Because the six previous editions have been widely used in courses in environmental health and related areas, an attempt has been made to maintain those characteristics that make it useful to scientists from other disciplines. This edition will again provide information on the many facets of toxicology, especially the principles, concepts, and modes of thoughts that are the foundation of the discipline. Mechanisms of toxicity are emphasized. "Here, you'll first get a skill-building review of the basic components of toxicology, including general principles, modes of action, and chemical-specific toxicity. The book then offers a revealing look at the systemic responses of toxic substances, before concluding with a two-part environmental toxicology chapter that puts air pollution and ecotoxicology into perspective."--Résumé de l'éditeur The most complete, trusted reference-text covering the full span of medical toxicology Market: Students, toxicologists, and pharmacologists Focuses on the principles, concepts, and modes of thought that are the foundation of the discipline New to this edition: updated throughout to reflect new understanding of cell death and drug metabolism, new content on chemical terrorism, many new contributors "Here, you'll first get a skill-building review of the basic components of toxicology, including general principles, modes of action, and chemical-specific toxicity. The book then offers a revealing look at the systemic responses of toxic substances, before concluding with a two-part environmental toxicology chapter that puts air pollution and ecotoxicology into perspective."--Jacket Equips you with the treatment of modern toxicology, including the principles, concepts, mechanisms, and modes of thought that are the foundation of the discipline. This work includes coverage of: the advances in molecular biology and pharmacogenetics; risk assessment; online references, in addition to traditional print journal and review articles. Toxicology has been defined as the study of the adverse effects of xenobiotics and thus is a borrowing science that has evolved from ancient poisoners. Title from PDF title page (viewed on Feb. 26, 2008).