Cardiovascular System

Front Matter....Pages 1-3 Clinical Pharmacology Methodology: Introduction....Pages 5-6 Direct Assessment of Cardiac Function....Pages 7-13 Use of the Systolic Time Intervals in Clinical Pharmacology....Pages 14-19 The Methodology of Blood Pressure Recording....Pages 20-28 Methods for the Assessment of the Effects of Drugs on Coronary Blood Flow in Man....Pages 29-39 Assessment of the Effect of Drugs on the Venous System in Man....Pages 40-45 The Electrocardiogram in the Assessment of the Effect of Drugs on Cardiac Arrhythmias....Pages 46-58 Methods for Assessment of the Effect of Drugs on Cerebral Blood Flow in Man....Pages 59-68 Methods for the Assessment of the Effects of Drugs on Renal Blood Flow....Pages 69-78 Methods of the Assessment of the Effect of Drugs on Liver Blood Flow in Man....Pages 79-85 Methods for the Assessment of the Effects of Drugs on the Arterial System in Man....Pages 86-92 Use of M-Mode Echocardiography in Clinical Pharmacology....Pages 93-99 Non-Invasive Assessment of the Effects of Drugs on Acute Myocardial Infarct Size in Man....Pages 100-106