Cardiac Regeneration and Repair: Biomaterials and Tissue Engineering (Woodhead Publishing Series in Biomaterials)

Cardiac Regeneration and Repair, Volume Two reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure. Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels. Cardiac Regeneration and Repair, Volume Two is complemented by an initial volume covering pathology and therapies. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials. Surveys the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Focuses on tissue engineering for cardiac repair including clinical considerations for cardiac tissue engineering Explores vascular remodeling, highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels Content: Front matter , Pages i-iii Copyright , Page iv Contributor contact details , Pages xi-xiv , R.-K. Li, R.D. Weisel, M. Xing, J.J. Wang, K.L. Christman, L. Reis, L.L.Y. Chiu, N. Feric, L. Fu, M. Radisic, B. McNeill, R. Tiwari-Pandey, M. Ruel, E.J. Suuronen, C. Zhu, T.D. Vu, T. Kofidis, D.M. Faulk, S.A. Johnson, S.F. Badylak, D.O. Freytes, et al. Woodhead Publishing Series in Biomaterials , Pages xv-xviii Foreword , Pages xix-xx , Sailay Siddiqi, Mark A. Sussman Introduction , Pages xxi-xxii , Ren-Ke Li, Richard D. Weisel 1 - Nanotechnology and nanomaterials for cardiac repair , Pages 3-16 , M. Xing 2 - Hydrogels for cardiac repair , Pages 17-48 , J.J. Wang, K.L. Christman 3 - Injectable biomaterials for cardiac regeneration and repair , Pages 49-81 , L. Reis, L.L.Y. Chiu, N. Feric, L. Fu, M. Radisic 4 - Biomaterials for enhancing endothelial progenitor cell (EPC) therapy for cardiac regeneration , Pages 82-109 , B. McNeill, R. Tiwari-Pandey, M. Ruel, E.J. Suuronen 5 - Endothelial progenitor cell (EPC)-seeded intravascular stents , Pages 110-124 , C. Zhu 6 - Biomaterials and cells for cardiac tissue engineering , Pages 127-179 , T.D. Vu, T. Kofidis 7 - Decellularized biological scaffolds for cardiac repair and regeneration , Pages 180-200 , D.M. Faulk, S.A. Johnson, S.F. Badylak 8 - Biomaterial scaffolds for cardiac regeneration and repair derived from native heart matrix , Pages 201-224 , D.O. Freytes, A. Godier-Furnemont, Y. Duan, J.D. O’Neill, G. Vunjak-Novakovic 9 - Cell sheet engineering for cardiac repair and regeneration , Pages 225-234,235e-254e,235-247 , Y. Haraguchi, T. Shimizu, K. Matsuura, D. Chang, M. Yamato, T. Okano 10 - Maturation of functional cardiac tissue patches , Pages 248-282 , G.C. Engelmayr Jr., D. Zhang 11 - Vascularizing engineered tissues for in vivo and in vitro applications , Pages 283-298 , S.C. George 12 - Clinical considerations for cardiac tissue engineering , Pages 299-312 , W.-H. Zimmermann 13 - Aortic extra cellular matrix (ECM) remodeling , Pages 315-349 , J.B. Wheeler, J.A. Jones, J.S. Ikonomidis 14 - Cell–biomaterial interactions for blood vessel formation , Pages 350-388 , S. Kusuma, L.E. Dickinson, S. Gerecht 15 - Stem cells in tissue-engineered blood vessels for cardiac repair , Pages 389-409 , H. Kurobe, M.W. Maxfield, Y. Naito, C. Breuer, T. Shinoka 16 - Tissue-engineered cardiovascular grafts and novel applications of tissue engineering by self-assembly (TESATM) , Pages 410-451 , C. Mount, N. Dusserrre, T. McAllister, N. L’Heureux Index , Pages 453-464

Cardiac Regeneration and Repair, Volume Two reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure.

Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels.

Cardiac Regeneration and Repair, Volume Two is complemented by an initial volume covering pathology and therapies. Together, the two volumes of Cardiac Regeneration and Repair provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials.

• Surveys the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels.
• Focuses on tissue engineering for cardiac repair including clinical considerations for cardiac tissue engineering
• Explores vascular remodeling, highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels

__Cardiac Regeneration and Repair, Volume Two__ reviews the use of biomaterials, alone or combined with cell therapy, in providing tissue-engineered constructs to repair the injured heart and prevent or reverse heart failure. Part one explores the variety of biomaterials available for cardiac repair, including nanomaterials and hydrogels. Further chapters explore the use of biomaterials to enhance stem cell therapy for restoring ventricular function and generating stem cell-modified intravascular stents. Part two focuses on tissue engineering for cardiac repair, including chapters on decellularized biologic scaffolds, synthetic scaffolds, cell sheet engineering, maturation of functional cardiac tissue patches, vascularized engineered tissues for in vivo and in vitro applications, and clinical considerations for cardiac tissue engineering. Finally, part three explores vascular remodeling, including chapters highlighting aortic extracellular matrix remodeling, cell-biomaterial interactions for blood vessel formation, and stem cells for tissue-engineered blood vessels. __Cardiac Regeneration and Repair, Volume Two__ is complemented by an initial volume covering pathology and therapies. Together, the two volumes of __Cardiac Regeneration and Repair__ provide a comprehensive resource for clinicians, scientists, or academicians fascinated with cardiac regeneration, including those interested in cell therapy, tissue engineering, or biomaterials. Heart disease is the leading cause of death in the Western World and heart failure following a myocardial infarction continues to increase despite urgent revascularization. Cell therapy offered the promise to reverse cardiac injury and prevent heart failure, but the initial clinical trials were not as effective as anticipated. New approaches to restore ventricular function are urgently needed. Cardiac regeneration and repair Volume 2 reviews the use of biomaterials, alone or combined with cell therapy, to provide tissue engineered constructs to repair the injured heart and prevent or reverse h Annotation Heart disease is the leading cause of death in the UK and the United States. For those who survive heart disease, few recover completely. Cell therapies, tissue engineering, and biomaterials technologies have advanced and now offer the potential to reverse the damage caused by heart disease. Chapters in Volume 2 of this important set look at biomaterials and tissue engineering strategies for regeneration and repair. The concluding section reviews vascular modeling and regeneration Volume 2 of this important book provides readers with comprehensive information on biomaterials and tissue engineering as strategies for the repair and regeneration of the heart. Volume 1 of this important book provides readers with comprehensive information on the pathology of heart disease and the cell therapies available.