Cardiac Arrhythmias [recurso electrónico] From Basic Mechanism to State-of-the-Art Management

This book covers all the major aspects associated with pathophysiological development of cardiac arrhythmias (covering enhanced or suppressed automaticity, triggered activity, or re-entry), from basic concepts through disease association, limitations of current pharmacotherapy and implant therapies and on-going trials and analysis of new biomarkers based on current knowledge of cellular interaction and signalling. The book describes novel and state-of-the-art methods for differentiating between the major types of arrhythmia, structural abnormalities and current practice guidelines and determination of risk stratification associated with sudden cardiac death. A particular focus is on arrhythmias associated with atrial fibrillation and includes details of associations with cardiac disease, current detection, analysis and imaging and future perspectives.​ Front Matter....Pages i-xxiii Anatomy and Physiology of the Atrioventricular Node: Basic Concepts....Pages 1-3 Anatomy and Physiology of the Atrioventricular Node: What Do We Know Today?....Pages 5-18 Molecular Basis of Arrhythmias Associated with the Cardiac Conduction System....Pages 19-34 Functional Anatomy in Arrhythmias and Vascular Support of the Conduction System....Pages 35-42 Autonomic Control of Cardiac Arrhythmia....Pages 43-60 Neural Mechanisms of Arrhythmia....Pages 61-64 Understanding the Genetic Basis of Atrial Fibrillation: Towards a Pharmacogenetic Approach for Arrhythmia Treatment....Pages 65-75 Importance of Isthmus Structure in the Right Atrium....Pages 77-93 Channelopathies and Heart Disease....Pages 95-129 Late Open Artery Hypothesis and Cardiac Electrical Stability....Pages 131-144 The Clinical Utility of 12-Lead Resting ECG in the Era of Ablation Strategies....Pages 145-155 Long-Term ECG (Holter) Monitoring and Head-Up Tilt Test....Pages 157-163 Echocardiography in Arrhythmias....Pages 165-186 Electrophysiologic Testing and Cardiac Mapping....Pages 187-197 How to Differentiate Between AVRT, AT, AVNRT, and Junctional Tachycardia Using the Baseline ECG and Intracardiac Tracings....Pages 199-208 Recognizing the Origin of Ventricular Premature Depolarization During Sinus Rhythm and During Non-sustained Tachycardia....Pages 209-219 Detection and Management of Atrial Fibrillation in Patients with Stroke or TIA in Clinical Practice....Pages 221-236 Ventricular Arrhythmias During Acute Myocardial Ischemia/Infarction: Mechanisms and Management ....Pages 237-251 Arrhythmias and Hypertrophic Cardiomyopathy....Pages 253-264 Lai Tai, the Mysterious Death of Young Thai Men....Pages 265-277 Cardiac Arrest Arrhythmias....Pages 279-284 Electrical Storm: Recent Advances....Pages 285-292 Electrical Storm: Clinical Management....Pages 293-304 Cellular Pharmacology of Cardiac Automaticity and Conduction: Implications in Antiarrhythmic Drug Assessment....Pages 305-333 Biophysical and Molecular Targets....Pages 335-343 Proarrhythmia (Secondary)....Pages 345-350 Connexin-43 Expression: A Therapeutic Target for the Treatment of Ventricular Tachycardia....Pages 351-360 Biophysics of Modern Ablation Techniques and Their Limitations....Pages 361-367 Cardiac Imaging to Assist Complex Ablation Procedures....Pages 369-386 AVNRT Ablation: Significance of Anatomic Findings and Nodal Physiology....Pages 387-400 Mechanisms of Atrial Fibrillation....Pages 401-412 Importance of Left Atrial Imaging in Catheter Ablation of Atrial Fibrillation....Pages 413-418 Atrial Fibrillation Ablation: From Guidelines to Clinical Reality....Pages 419-438 Atrial Fibrillation: Should Cardiac Surgeons Be Consulted?....Pages 439-449 Atrial Arrhythmias After AF Ablation: Challenge for the Next Decade?....Pages 451-461 Cavotricuspid Isthmus Anatomy Particularities in Atrial Flutter Ablation....Pages 463-467 Location of Accessory Pathways in WPW: What and How Should We Ablate....Pages 469-487 VT Ablation: Importance of Linear Lesions and Late Potentials....Pages 489-496 Programmed Stimulation During Mapping and Ablation of VT....Pages 497-507 Catheter Ablation in Pediatric and Congenital Heart Disease....Pages 509-516 Interventional Electrophysiology in Patients with Congenital Heart Disease....Pages 517-523 Epicardial Mapping and Ablation of Cardiac Arrhythmias....Pages 525-531 Robotic Ablation in Electrophysiology....Pages 533-541 Strategies for Restoring Cardiac Synchrony by Cardiac Pacing....Pages 543-589 Device Therapy for Bradycardias....Pages 591-596 Pacemaker Dependence After Atrioventricular Node Ablation....Pages 597-604 Pacing Site: From Theory to Practice....Pages 605-611 Implantable Cardioverter Defibrillators in the Pediatric and Congenital Heart Population....Pages 613-618 Sensing Issues in CRT Devices....Pages 619-628 Cardiac Resynchronization Therapy: Do Benefits Justify the Costs and Are They Sustained Over the Long Term?....Pages 629-638 Complications of Cardiac Implantable Electronic Devices (CIED)....Pages 639-651 Peri-device Implantation Anticoagulation Management: Evidence and Clinical Implications....Pages 653-664 Back Matter....Pages 665-678 The past 50 years have witnessed the growth and evolution of clinical electrophysiology from a field whose goals were simply to understand of the mechanisms of arrhythmia to one of significant therapeutic impact. The development and refinement of implantable devices and catheter ablation have made non-pharmacological therapy a treatment of choice for most arrhythmias encountered in clinical practice. Cardiac Arrhythmias: From Basic Mechanism To State-of-the-Art Management provides an electrophysiologic approach to arrhythmias predicated on the hypothesis that a better understanding of the mechanisms of arrhythmias will lead to more successful and rationally chosen therapy. It encompasses the anatomy of arrhythmias, diagnostic methods, comorbid diseases, and the treatment of all forms of cardiac arrhythmias. It discusses modern ablation and mapping techniques, while reviews the methodology required to define the mechanism and site of origin of arrhythmias, so that safe and effective therapy can be chosen. It will thus be of interest to all involved in the management of these patients, from clinical cardiac electrophysiologists themselves to clinical cardiologists, interventionalists, cardiac surgeons, emergency medicine physicians and researchers in basic cardiac science Anatomy And Physiology Of The Atrioventricular Node -- Molecular Basis Of Arrhythmias Associated With The Cardiac Conduction System -- Neural Mechanisms Of Arrhythmia -- Late Open Artery Hypothesis And Cardiac Electrical Stability -- Echocardiography In Arrhythmias -- Detection And Management Of Atrial Fibrillation In Patients With Stroke Or Tia In Clinical Practice -- Lai Tai, The Mysterious Death Of Young Thai Men -- Electrical Storm: Recent Advances -- Biophysical And Molecular Targets -- Cardiac Imaging To Assist Complex Ablation Procedures -- Atrial Fibrillation Ablation: From Guidelines To Clinical Reality -- Location Of Accessory Pathways In Wpw: What And How Should We Ablate -- Catheter Ablation In Pediatric And Congenital Heart Disease -- Srategies For Restoring Cardiac Synchrony By Cardiac Pacing -- Implantable Cardioverter Defibrillators In The Pediatric And Congenital Heart Population -- Peri-device Implantation Anticoagulation Management: Evidence And Clinical Implications. Ambrose S. Kibos, Bradley P. Knight, Vidal Essebag, Steven B. Fishberger, Mark Slevin, Ion C. Tintoiu, Editors. Includes Bibliographical References And Index. Mode Of Access: World Wide Web.