Carcinoma of the Oral Cavity and Oropharynx (Recent Results in Cancer Research Book 134)

In spite of great advance made by ENT and maxillofacial surgeons as well as radiotherapists to improve therapy of cancer of the oral cavity and oropharynx, it has not been possible in the past 4 decades to raise the chances of patient survival above 40%-45%. However, recent studies with different combination therapies indicate that better results can be expected in the future. In this volume, the current status and results of therapeutic studies are presented by distinguished clinicians in the three disciplines. The book provides up-to-date information and encourages interdisciplinary cooperation. Front Matter....Pages I-XVI Epidemiology of Cancer of the Oral Cavity and Oropharynx....Pages 1-8 Clinical Relevance of Precancerous Lesions of Oral Mucosa....Pages 9-16 Extended Surgery for Advanced Maxillary Sinus Carcinoma....Pages 17-24 Resection of Tumors in Tongue, Floor of the Mouth, and Mandible: Possibilities of Primary Reconstruction....Pages 25-35 Surgery of Oropharyngeal Cancer....Pages 37-41 Surgical Management of Cervical Lymph Nodes in Patients with Oral and Oropharyngeal Cancer....Pages 43-55 Radical Neck Dissection Versus Conservative Neck Dissection for Squamous Cell Carcinoma of the Oral Cavity....Pages 57-62 Treatment of Oropharynx Carcinomas: Experience at the Institut Gustave-Roussy....Pages 63-68 Concomitant Boost-Accelerated, Superfractionated Irradiation for the Treatment of Advanced Carcinomas of the Oral Cavity and Oropharynx....Pages 69-79 Regional Lymph Node Irradiation....Pages 81-87 Radiotherapy with Different Fractionations and Simultaneous Cisplatin or Carboplatin in the Treatment of Advanced Head and Neck Carcinomas: Clinical Results and Radiobiological Investigations....Pages 89-99 Curietherapy Versus External Irradiation Combined with Curietherapy in Stage II Squamous Cell Carcinomas of Mobile Tongue and Floor of Mouth....Pages 101-110 Present Status of EORTC Trials of Hyperfractionated and Accelerated Radiotherapy on Head and Neck Carcinoma....Pages 111-119 Second Primary Tumors in Oral and Oropharyngeal Cancer....Pages 121-132 Induction Chemotherapy for Organ Preservation in Advanced Squamous Cell Carcinoma of the Oral Cavity and Oropharynx....Pages 133-143 Carcinomas of the Oropharynx Treated with Hyperfractionated Radiation Therapy on Radiation Therapy Oncology Group Protocol 8313....Pages 145-154 Preoperative Radiochemotherapy and Radical Surgery of Advanced Head and Neck Cancers — Results of a Prospective, Multicenter DÖSAK Study....Pages 155-163 Simultaneous Preoperative Radiochemotherapy with Cisplatin in Advanced Oral Cavity Carcinomas: Acute Response and Follow-Up....Pages 165-172 Results from DÖSAK Observational Studies....Pages 173-182 Current Trends in Therapeutic Research....Pages 183-190 The Radiobiology, Treatment, and Prevention of Osteoradionecrosis of the Mandible....Pages 191-199 Epiprosthetic Rehabilitation: Patient’s Acceptance of a Facial Epithesis Following Tumor Surgery....Pages 201-204 Value of Follow-Up in Patients Treated for Squamous Cell Carcinomas of the Oral Cavity and Oropharynx....Pages 205-214 Back Matter....Pages 215-217 This volume reviews the current status and results of therapeutic studies into cancer of the oral cavity and oropharynx. The clinicians contributing to this study explore the results of trials with a variety of combined therapies.