Carbonic Anhydrase: Its Inhibitors and Activators (Taylor & Francis Medicinal Chemistry Series)

carbonic Anhydrase: Its Inhibitors And Activators Provides A State-of-the-art Overview Of The Latest Developments And Challenges In Carbonic Anhydrase Research. Authors Describe The Mechanisms Of Action Of Specific Inhibitors In Relation To Physiological Function, And Present Previously Unpublished Research On Ca Activators. Written By A Team Of Internationally Recognized Experts, This Authoritative Edition Is A Leading Reference For Bioscientists Across Many Disciplines, As Well As Novices Interested In The Latest Developments In This Complex Field. An Understanding Of The Mechanisms Through Which Carbonic Anhydrases Interact With Their Inhibitors And Activators In Complex Biological Environments Is Essential In Developing Novel Therapeutic Agents For The Treatment Of Disease. "Written by a team of internationally recognized experts, this edition is a reference for bioscientists across many disciplines, as well as novices interested in the latest developments in this complex field. An understanding of the mechanisms through which carbonic anhydrases interact with their inhibitors and activators in complex biological environments is essential in developing novel therapeutic agents for the treatment of disease."--BOOK JACKET. This book provides a state-of-the-art overview of the developments in CA and CA-inhibitor research and will be of great interest to medicinal chemists, pharmacologists and professionals involved in novel drug design At least 14 different -carbonic anhydrase (CA, EC 4.2.1.1) isoforms have been isolated in higher vertebrates, wherein these zinc enzymes play crucial physiological roles.