\_\_Candida\_\_ and Candidiasis

Reviews All Aspects Of This Common Fungal Pathogen And Its Impact On Human Health, From The Basic Biology Of Candida Albicans To The Clinical Management Of Candidiasis. Reviews The Latest Basic And Clinical Research, Focusing On Findings In Genome Variability, Host-pathogen Interactions, Antifungal Resistance And Drug Discovery, And Diagnostics To Foster Better Understanding And Treatment Of Candidiasis. Examines Recent Discoveries That Have Shed Light On Morphogenesis And The Cell Cycle, Including How New Findings On Host Responses May Have Applications For The Diagnosis Of Blood-borne Candidiasis. Candida: What Should Clinicians And Scientists Be Talking About? / Brad Spellberg, Kieren A. Marr, And Scott G. Filler -- An Introduction To The Medically Important Candida Species / Gary Moran, David Coleman, And Derek Sullivan -- Comparative Genomics Of Candida Species / Geraldine Butler -- The Genetic Code Of The Candida Ctg Clade / Ana Catarina Gomes, Gabriela R. Moura, And Manuel A. S. Santos -- Genome Instability And Dna Repair / Germán Larriba And Richard A. Calderone -- Switching And Mating / David R. Soll -- Detection And Clinical Significance Of Variability Among Candida Isolates / Lois L. Hoyer -- Cell Cycle And Growth Control In Candida Species / Cheryl A. Gale And Judith Berman -- Immunology Of Invasive Candidiasis / Luigina Romani -- Mucosal Immunity To Candida Albicans / Paul L. Fidel, Jr. And Mairi C. Noverr -- Innate Immunity To Candida Infections / Mihai G. Netea And Neil A. R. Gow -- Vaccines And Passive Immunity Against Candidiasis / Brad Spellberg, Yue Fu, And Ashraf S. Ibrahim -- Salivary Histatins: Structure, Function, And Mechanisms Of Antifungal Activity / Woon Sik Jang And Mira Edgerton -- The Cell Wall: Glycoproteins, Remodeling, And Regulation / Carol Munro And Mathias L. Richard -- Stress Responses In Candida / Alistair J. P. Brown ... [et Al.] -- Adhesins In Opportunistic Fungal Pathogens / Rebecca Zordan And Brendan Cormack -- Encounters With Mammalian Cells: Survival Strategies Of Candida Species / Slavena Vylkova And Michael C. Lorenz -- Gene Expression During The Distinct Stages Of Candidiasis / Duncan Wilson, Francois Mayer, And Bernhard Hube -- Biofilm Formation In Candida Albicans / Jonathan Sewell Finkel And Aaron P. Mitchell -- Candida Spp. In Microbial Populations And Communities: Molecular Interactions And Biological Importance / Amy E. Piispanen And Deborah A. Hogan -- Back To The Future: Candida Mitochondria And Energetics / Deepu Alex, Richard Calderone, And Dongmei Li -- Antifungals: Drug Class, Mechanisms Of Action, Pharmacokinetics/pharmacodynamics, Drug-drug Interactions, Toxicity, And Clinical Use / Jeniel E. Nett And David R. Andes -- The Impact Of Antifungal Drug Resistance In The Clinic / Russell E. Lewis And Dimitrios P. Kontoyiannis -- Insights In Antifungal Drug Discovery / Françoise Gay-andrieu ... [et Al.] -- Multidrug Resistance Transcriptional Regulatory Networks In Candida / P. David Rogers And Katherine S. Barker -- Mucosal Candidiasis / Sanjay G. Revankar And Jack D. Sobel -- Systemic Candidiasis: Candidemia And Deep-organ Infections / Cornelius J. Clancy And M. Hong Nguyen -- New Developments In Diagnostics And Management Of Invasive Candidiasis / Sujatha Krishnan And Luis Ostrosky-zeichner -- The Epidemiology Of Invasive Candidiasis / Michael A. Pfaller And Daniel J. Diekema -- Cool Tools 1: Development And Application Of A Candida Albicans Two-hybrid System / Bram Stynen, Patrick Van Dijck, And Hélène Tournu -- Cool Tools 2: Development Of A Candida Albicans Cell Surface Protein Microarray / A. Brian Mochon -- Cool Tools 3: Large-scale Genetic Interaction Screening In Candida Albicans / Yeissa Chabrier-roselló, Anuj Kumar, And Damian Krysan -- Cool Tools 4: Imaging Candida Infections In The Live Host / Soumya Mitra, Thomas H. Foster, And Melanie Wellington -- Cool Tools 5: The Candida Albicans Orfeome Project / Mélanie Legrand, Carol Munro, And Christophe D'enfert. Edited By Richard A. Calderone, Cornelius J. Clancy. Includes Bibliographical References And Index. Content: Candida: what should clinicians and scientists be talking about? / Brad Spellberg, Kieren A. Marr, and Scott G. Filler -- An introduction to the medically important Candida species / Gary Moran, David Coleman, and Derek Sullivan -- Comparative genomics of Candida species / Geraldine Butler -- The genetic code of the Candida CTG clade / Ana Catarina Gomes, Gabriela R. Moura, and Manuel A. S. Santos -- Genome instability and DNA repair / Germán Larriba and Richard A. Calderone -- Switching and mating / David R. Soll -- Detection and clinical significance of variability among Candida isolates / Lois L. Hoyer -- Cell cycle and growth control in Candida species / Cheryl A. Gale and Judith Berman -- Immunology of invasive candidiasis / Luigina Romani -- Mucosal immunity to Candida albicans / Paul L. Fidel, Jr. and Mairi C. Noverr -- Innate immunity to Candida infections / Mihai G. Netea and Neil A. R. Gow -- Vaccines and passive immunity against candidiasis / Brad Spellberg, Yue Fu, and Ashraf S. Ibrahim -- Salivary histatins: structure, function, and mechanisms of antifungal activity / Woon Sik Jang and Mira Edgerton -- The cell wall: glycoproteins, remodeling, and regulation / Carol Munro and Mathias L. Richard -- Stress responses in Candida / Alistair J. P. Brown ... [et al.] -- Adhesins in opportunistic fungal pathogens / Rebecca Zordan and Brendan Cormack -- Encounters with mammalian cells: survival strategies of Candida species / Slavena Vylkova and Michael C. Lorenz -- Gene expression during the distinct stages of candidiasis / Duncan Wilson, Francois Mayer, and Bernhard Hube -- Biofilm formation in Candida albicans / Jonathan Sewell Finkel and Aaron P. Mitchell -- Candida spp. in microbial populations and communities: molecular interactions and biological importance / Amy E. Piispanen and Deborah A. Hogan -- Back to the future: Candida mitochondria and energetics / Deepu Alex, Richard Calderone, and Dongmei Li -- Antifungals: drug class, mechanisms of action, pharmacokinetics/pharmacodynamics, drug-drug interactions, toxicity, and clinical use / Jeniel E. Nett and David R. Andes -- The impact of antifungal drug resistance in the clinic / Russell E. Lewis and Dimitrios P. Kontoyiannis -- Insights in antifungal drug discovery / Françoise Gay-Andrieu ... [et al.] -- Multidrug resistance transcriptional regulatory networks in Candida / P. David Rogers and Katherine S. Barker -- Mucosal candidiasis / Sanjay G. Revankar and Jack D. Sobel -- Systemic candidiasis: candidemia and deep-organ infections / Cornelius J. Clancy and M. Hong Nguyen -- New developments in diagnostics and management of invasive candidiasis / Sujatha Krishnan and Luis Ostrosky-Zeichner -- The epidemiology of invasive candidiasis / Michael A. Pfaller and Daniel J. Diekema -- Cool tools 1: development and application of a Candida albicans two-hybrid system / Bram Stynen, Patrick Van Dijck, and Hélène Tournu -- Cool tools 2: development of a Candida albicans cell surface protein microarray / A. Brian Mochon -- Cool tools 3: large-scale genetic interaction screening in Candida albicans / Yeissa Chabrier-Roselló, Anuj Kumar, and Damian Krysan -- Cool tools 4: Imaging Candida infections in the live host / Soumya Mitra, Thomas H. Foster, and Melanie Wellington -- Cool tools 5: the Candida albicans ORFeome project / Mélanie Legrand, Carol Munro, and Christophe D'Enfert. Abstract: Should become the standard reference work on Candida and candidiasis, the most prevalent fungal infection in humans. Read more...