Cancer risks : strategies for elimination ; [Conference on Strategies for the Eliminiation of Cancer Risks, Heidelberg in June 1986

A large body of information about possible causes of cancer has been ac­ cumulated by both clinical experience in man and observations in animal experiments. There is general agreement that in most cases cancer is due to exogenous factors, albeit the genetic disposition may also play an impor­ tant part. Three main categories of exogenous risk factors have been iden­ tified, namely chemicals, radiation, and viruses. In principle, it should be possible to prevent cancer by eliminating such risk factors. However, in spite of the rapidly growing number of well established risk factors, many shortcomings in our understanding of the causes of human cancer and in the introduction of effective preventive measures are evident. In addition to obvious gaps in our scientific knowledge, inadequacies in personal life style, irresponsible handling of environmental contaminants, and in some areas also deficiencies in political decisions seriously hamper the elimina­ tion of risk factors for cancer. It was this background which prompted the Committee coordinating Cancer Research in the GroBforschungseinrichtungen in the Federal Re­ public of Germany to organize a conference on Strategies for the Elimina­ tion of Cancer Risks. The conference was held in Heidelberg in June 1986. In areas which appeared to be especially pertinent to public health, author­ itative speakers presented the state of the art and prepared the basis for the discussion. Both the presentations of the speakers and the summaries of the discussions are contained in this book. Front Matter....Pages I-XIII Front Matter....Pages 1-1 Genetic Predisposition for Cancer Risks in Man....Pages 3-13 The Role of Epidemiology in the Detection and Reduction of Cancer Risks....Pages 14-23 Back Matter....Pages 24-24 Front Matter....Pages 25-25 Assessment of Cancer Risk from Chemicals....Pages 27-32 Validity of Short-Term Tests to Detect Carcinogenic Chemicals....Pages 33-46 Preneoplastic Lesions as Indicators of the Carcinogenic Risk Caused by Chemicals....Pages 47-64 Carcinogenic Risk Assessment: Are Animals Good Surrogates for Man?....Pages 65-79 Back Matter....Pages 80-83 Front Matter....Pages 85-85 Possibilities of Primary Prevention Against Chemical Carcinogens....Pages 87-93 Primary Prevention Against Occupational Carcinogens....Pages 94-100 Chemical Carcinogens in Tobacco....Pages 101-113 Primary Prevention of Tobacco-Related Cancer....Pages 114-132 Back Matter....Pages 133-134 Front Matter....Pages 135-135 Cancer Risk from Ultraviolet Radiation....Pages 137-142 Assessment of Cancer Risks Due to Ionizing Radiations....Pages 143-153 Cancer Risk from Environmental Radioactivity....Pages 154-165 Back Matter....Pages 166-168 Front Matter....Pages 169-169 Viruses in Human Tumors....Pages 171-180 Strategies in the Prevention of Infections by Oncogenic Viruses....Pages 181-189 Back Matter....Pages 190-191 Summary of Round Table Discussion on Strategies Against Tobacco Cancer....Pages 192-193 Back Matter....Pages 195-199 Edited By Peter Bannasch. Presentations And Summaries Of Discussions From A Conference Held In Heidelberg, June 1986, And Organized By The Committee Coordinating Cancer Research In The Grossforschungseinrichtungen. Includes Bibliographies And Index.