Cancer neurology in clinical practice : neurological complications of cancer and its treatment

This updated edition provides clinicians from various backgrounds and levels of training the information needed to optimally diagnose and manage neurologic complications of the nervous system. Organized into seven sections, this comprehensive volume begins with an overview of diagnostic studies for neurologic complications involving the nervous system. That is followed by sections on metastatic and non-metastatic complications of cancer involving the nervous system, and the interpretation, diagnosis, and management of common neuro-oncologic symptoms. The next section reviews the neurologic complications of cancer therapy, including corticosteroids, radiation therapy, chemotherapy, targeted molecular therapies, immunotherapies, hematopoietic stem cell transplantation, and infections involving the nervous system. The final section focuses on the most important neurologic complications in cancers arising from specific organs. In addition to capturing the latest advancements in the rapidly evolving fields of oncology and cancer neurology, the goal of this resource is to lead clinicians toward prompt diagnosis and intervention in order to improve patient quality of life. "This textbook is a valuable resource for medical oncologists and radiation oncologists, as well as neurologists and neuro-oncologists dealing with these patients. ... Overall, the chapters are well organized, clearly written, fairly balanced, and reasonably up to date. ... I would recommend it as a learning tool to physicians in training (medical students, residents, and fellows) and for more experienced physicians as both a review/ update and a way to gain more in-depth knowledge and insight into the neurologic problems of cancer patients." (John C. Flickinger, International Journal of Radiation Oncology Biology Physics, Vol. 73 (2), 2009) "The general organization of the book is logical and facilitates its practical and everyday use. ... Overall this textbook is very comprehensive and encompasses main neuro-oncological challenges. ... Schiff, Kesari and Wen have edited a very elegant and highly practical textbook, written by recognized authorities in their respective fields, which will be used by a wide range of medical and surgical specialists who are confronted on a daily basis with neurological manifestations of cancer in their practice." (I. Radovanovic and G. Zadeh, British Journal of Cancer, Vol. 100 (6), 2009) Front Matter ....Pages i-xviii Front Matter ....Pages 1-1 The Prevalence and Impact of Neurological Disease in Cancer (Andrew L. Lin, Lisa M. DeAngelis)....Pages 3-10 Front Matter ....Pages 11-11 Imaging Neurologic Manifestations of Oncologic Disease (Raymond Huang, Patrick Y. Wen)....Pages 13-31 Other Diagnostic Tools for Neurological Disease in Cancer: EEG, EMG, and Lumbar Puncture (Crystal S. Janani, Edward K. Avila)....Pages 33-54 Front Matter ....Pages 55-55 Brain Metastasis as Complication of Systemic Cancers (Riccardo Soffietti, Federica Franchino, Roberta Rudà)....Pages 57-79 Leptomeningeal Metastasis as Complication of Systemic Cancers (Sophie Taillibert, Emilie Le Rhun, Marc C. Chamberlain)....Pages 81-111 Spinal Metastasis as Complication of Systemic Cancers (Gregory Davis, Michaela Lee, Dawit Aregawi, Mark E. Shaffrey, David Schiff, Jonathan H. Sherman)....Pages 113-125 Peripheral Nervous System Metastases as Complications of Systemic Cancer (Amanda C. Guidon)....Pages 127-139 Front Matter ....Pages 141-141 Headache as Complication of Cancer (Surabhi Ranjan, David Schiff)....Pages 143-151 Seizures as Complications in Cancer (Christa P. Benit, Melissa Kerkhof, Alberto Duran-Peña, Charles J. Vecht)....Pages 153-169 Cerebrovascular Complications of Cancer (Lisa R. Rogers)....Pages 171-191 Elevated Intracranial Pressure and Hydrocephalus in Brain Tumor Patients (Matthew E. Shuman, Mark D. Johnson)....Pages 193-202 Cognitive Dysfunction, Mood Disorders, and Fatigue as Complications of Cancer (Jörg Dietrich, Michael W. Parsons)....Pages 203-219 Paraneoplastic Syndromes of the Nervous System as Complications of Cancer (Myrna R. Rosenfeld, Josep Dalmau)....Pages 221-238 Front Matter ....Pages 239-239 Neurologic Complications of Radiation Therapy (Damien Ricard, Thomas Durand, Arnault Tauziède-Espariat, Delphine Leclercq, Dimitri Psimaras)....Pages 241-273 Neurological Complications of Chemotherapy (Craig A. Vargo, Leslie A. Ray, Herbert B. Newton)....Pages 275-310 Neurological Complications of Targeted Therapies (Deborah A. Forst, Patrick Y. Wen)....Pages 311-333 Neurological Complications of Immune-Based Therapies (Martha R. Neagu, Russell W. Jenkins, David Reardon)....Pages 335-344 Neurologic Complications of Hematopoietic Stem Cell Transplantation (Eudocia Q. Lee, Patrick Y. Wen)....Pages 345-357 Neurologic Complications of Corticosteroids in Cancer Therapy (Erin M. Dunbar, Yue Wang, Santosh Kesari)....Pages 359-376 Central Nervous System Infections in Patients Receiving Cancer Therapies (Amy A. Pruitt)....Pages 377-396 Front Matter ....Pages 397-397 Neurological Complications of Primary Brain Tumors (Justin T. Jordan, Thomas N. Byrne, Tracy Batchelor)....Pages 399-416 Neurological Complications of Lung Cancer (Ming Chi, Manmeet S. Ahluwalia)....Pages 417-434 Neurological Complications of Breast Cancer and Its Treatment (Emilie Le Rhun, Sophie Taillibert, Marc C. Chamberlain)....Pages 435-469 Neurologic Complications of Gastrointestinal Cancer (Rajiv Magge, Eli L. Diamond)....Pages 471-484 Neurologic Complications of Genitourinary Cancer (Jennie W. Taylor)....Pages 485-495 Neurologic Complications of Female Reproductive Tract Cancers (K. Ina Ly, Maciej M. Mrugala)....Pages 497-513 Neurological Complications of Sarcomas (Megan L. Kruse, David M. Peereboom)....Pages 515-526 Neurologic Complications of Head and Neck Cancer (Sepideh Mokhtari, Thomas J. Kaley)....Pages 527-539 Neurological Complications of Malignant Melanoma (Hamza Malek, Annise Wilson, Jeffrey Raizer)....Pages 541-557 Neurological Complications of Leukemia (Joachim M. Baehring, Amy M. Chan)....Pages 559-569 Neurologic Complications of Lymphoma (Lakshmi Nayak, Christian Grommes)....Pages 571-581 Neurologic Complications of Plasma Cell Dyscrasias (Elie Naddaf, Michelle L. Mauermann)....Pages 583-595 Neurologic Complications of Pediatric Systemic Cancer (Elizabeth S. Duke, Scott L. Pomeroy, Nicole J. Ullrich)....Pages 597-614 Front Matter ....Pages 615-615 Neurological Complications of Cancer and Cancer Therapies in Long-Term Survivors (Isabel Arrillaga)....Pages 617-625 Back Matter ....Pages 627-643