Cancer in Children and Young People: Acute Nursing Care (Wiley Series in Nursing)

Much has changed since the first book __Paediatric Oncology: Acute Nursing Care__ (1999), therefore, this new edition encompasses these changes in relation to the practice itself and the evidence that underpins it. Emphasis is placed on ensuring terminology is accurate, in keeping with the language of the current day. The book is divided into six sections: Chemotherapy, Haematopoetic Stem Cell Transplantation, General Surgery, Radiotherapy, Late Effects of cancer therapies, and Palliative Care. There is a brief commentary at the end of each section/chapter by a ‘novice’ author but experienced practitioner, highlighting to the reader what is already known and what the section/chapter adds to their current knowledge and practice. Content: Chapter 1 Principles of Chemotherapy (pages 7–13): Angela HoulstonChapter 2 Chemotherapy Agents (pages 15–19): Angela HoulstonChapter 3 Administration of Chemotherapy (pages 21–34): Angela HoulstonChapter 4 Side Effects of Chemotherapy (pages 35–71): Karen SelwoodChapter 5 Oncological Emergencies (pages 73–84): Karen SelwoodChapter 6 Future Trends (pages 85–90): Karen SelwoodChapter 7 Background to the Haematopoietic Stem Cell Transplant (HSCT) Procedure (pages 97–106): Nikki Bennett?Rees and Sian HopkinsChapter 8 Preparation for Bone Marrow Transplant (pages 107–124): Nikki Bennett?Rees, Sian Hopkins and Joanna StoneChapter 9 Collection and Infusion of Bone Marrow, Peripheral Blood Stem Cells and Umbilical Cord Cells (pages 125–133): Nikki Bennett?Rees and Sian HopkinsChapter 10 Protective Isolation: Nursing Issues (pages 135–142): Nikki Bennett?Rees and Sian HopkinsChapter 11 Complications of Stem Cell Transplant (pages 143–162): Nikki Bennett?Rees and Sian HopkinsChapter 12 Discharge Planning and Psychosocial Issues for the Family (pages 163–168): Nikki Bennett?Rees and Sian HopkinsChapter 13 Staff Support in Stem Cell Transplant Units (pages 169–172): Sian HopkinsChapter 14 Further Developments in Stem Cell Transplantation (pages 173–179): Nikki Bennett?Rees, Sian Hopkins, Lesley Henderson and Jinhua Xu?BayfordChapter 15 General Surgery (pages 187–217): Rachel Hollis, Sharon Denton and Gill ChapmanChapter 16 Neuro?Oncology (pages 223–249): Lindy May and Beth WardChapter 17 Primary Bone Cancer in Young People (pages 255–277): Chris HenryChapter 18 The Nature of Radiotherapy (pages 279–288): Monica HopkinsChapter 19 Administration of Radiotherapy (pages 289–309): Monica HopkinsChapter 20 Tumours and Radiotherapy Treatment (pages 311–320): Monica Hopkins and Cornelia ScottChapter 21 Acute and Sub?Acute Side Effects of Radiotherapy (pages 321–341): Monica Hopkins and Cornelia ScottChapter 22 The Role of Radiotherapy in Palliative Care (pages 343–349): Monica HopkinsChapter 23 Overview of Long?Term Follow?Up (pages 351–355): Susan MehtaChapter 24 Potential Physical Issues Following Cancer Treatment (pages 357–381): Ruth Elson and Susan MehtaChapter 25 The Role of the Nurse in Long?Term Follow?Up (pages 383–388): Beverly HorneChapter 26 Health Promotion for Long?Term Follow?Up Patients (pages 389–396): Beverly HorneChapter 27 Quality of Life in Long?Term Survivors of Childhood Cancer (pages 397–404): Anthony Penn Cancer in Children and Young People......Page 3 Contents......Page 7 Preface......Page 13 Foreword......Page 15 Contributors......Page 17 Acknowledgements......Page 19 Part 1 Chemotherapy......Page 21 Commentary: Chemotherapy......Page 23 Cell cycle......Page 27 Growth fraction......Page 28 Protocol development and clinical trials......Page 29 Considerations when planning chemotherapy treatments......Page 30 Treatment approaches......Page 31 References......Page 33 Classification of drugs......Page 35 References......Page 39 Safe handling......Page 41 Personal Protective Equipment (PPE)......Page 42 Work practices......Page 43 Setting for chemotherapy administration......Page 45 Administration of chemotherapy......Page 47 Routes of administration......Page 48 Intrathecal route......Page 51 The intramuscular and subcutaneous routes......Page 52 References......Page 53 Introduction......Page 55 Gastrointestinal tract......Page 56 Taste alteration......Page 62 Nausea and vomiting......Page 63 Pharmacological interventions......Page 66 Anorexia/weight loss......Page 68 Haematological problems......Page 75 Viral infections......Page 80 Cutaneous side effects......Page 81 References......Page 85 Septic shock......Page 93 Home care......Page 94 Disseminated intravascular coagulation (DIC)......Page 95 Acute tumour lysis syndrome (ATLS)......Page 97 Hyperuricaemia......Page 99 Hyperkalaemia......Page 100 Nursing implications of ATLS......Page 101 References......Page 102 Introduction......Page 105 Targeted approaches......Page 106 Gene therapy......Page 107 New treatments for cancer – the nurse’s role......Page 108 References......Page 109 Part 2 Haematopoietic Stem Cell Transplantation......Page 111 Commentary: Haematopoietic Stem Cell Transplantation......Page 113 History......Page 117 Types of transplant......Page 118 Diseases for which haematopoietic stem cell transplant is a treatment modality......Page 119 Tissue typing......Page 120 Adult unrelated donors......Page 122 References......Page 125 The family......Page 127 Support......Page 129 Preparation of children......Page 130 Conditioning regimens......Page 133 Preparation of a sibling donor......Page 136 Ethical use of sibling donors......Page 137 Saviour siblings......Page 141 References......Page 142 Collection of bone marrow......Page 145 Collection of peripheral blood stem cells (PBSC)......Page 146 Venous access......Page 148 Stem cell collection......Page 149 Collection of umbilical cord blood cells......Page 150 Bone marrow/stem cell infusion......Page 151 References......Page 153 Introduction......Page 155 Infection prophylaxis......Page 156 Protective isolation......Page 157 Dietary restrictions......Page 158 Mouth care......Page 159 The effects of isolation......Page 160 References......Page 161 Mucositis......Page 163 Treatment and nursing implications......Page 164 Haematological complications......Page 167 Infection......Page 170 Veno-occlusive disease......Page 174 Graft versus host disease (GVHD)......Page 176 Graft versus leukaemia (GVL)......Page 179 References......Page 180 Discharge planning......Page 183 Psychosocial effects of stem cell transplant on the family......Page 186 References......Page 188 13. Staff Support in Stem Cell Transplant Units......Page 189 Educational needs of nurses in blood and bone marrow transplant units......Page 190 References......Page 191 What is gene therapy?......Page 193 What does the gene therapy process involve for the child?......Page 194 Care of the child undergoing gene therapy for X-linked SCID......Page 196 Care of the child undergoing gene therapy for ADA-SCID or CGD......Page 197 Risks and side effects of gene therapy......Page 198 References......Page 199 Part 3 Surgery......Page 201 Continuity of care......Page 203 Pain......Page 204 Central venous access......Page 205 References......Page 206 Introduction......Page 207 The challenge of surgical care in paediatric oncology......Page 208 Surgery as a diagnostic tool......Page 209 Surgery as a treatment modality......Page 212 Preparing the child and the family for surgery......Page 218 Post-operative nursing care......Page 221 Late effects of surgical treatment......Page 226 Surgery in supportive care......Page 228 Management of infection......Page 232 Surgery to avoid the complications of radiotherapy......Page 233 References......Page 234 Commentary: Neuro-oncology......Page 239 Overview of brain tumours......Page 243 Increased intracranial pressure and hydrocephalus......Page 245 Tumour types......Page 246 Investigations into brain tumours......Page 247 Neurological assessment......Page 248 The multidisciplinary team......Page 252 Intra-operative care......Page 253 Post-operative management......Page 254 Jack’s journey through CNS tumour treatment......Page 256 Ongoing needs of a child with a brain tumour......Page 257 Adjuvant treatment: specifics of treating a child with a CNS tumour......Page 259 Late effects of CNS tumours and acute rehabilitation needs......Page 262 Discharge planning......Page 264 Palliative care......Page 265 The future of neuro-oncology......Page 266 References......Page 267 Commentary: Primary Bone Cancer in Young People......Page 271 Introduction......Page 275 Types of tumours and their presentation......Page 277 Treatment options......Page 280 Limb conservation surgery......Page 282 Amputation......Page 285 Discharge planning......Page 288 Late effects......Page 289 Future trends......Page 292 Impact of setting......Page 293 References......Page 295 Part 4 Radiotherapy......Page 299 Introduction......Page 301 The nature of radiation......Page 302 Artificial production of radiation for clinical use......Page 303 Effect of ionising radiation on human tissue......Page 304 Hazards to healthy tissue during radiotherapy......Page 305 References......Page 306 External beam therapy (teletherapy)......Page 309 Brachytherapy......Page 317 Use of unsealed sources (intravenous radioactive materials)......Page 319 Administration of alternative radiotherapy techniques......Page 322 What does the future hold for radiotherapy?......Page 324 References......Page 326 Brain tumours......Page 331 Adverse effects of radiotherapy in the treatment of brain tumours......Page 332 Acute lymphoblastic leukaemia with CNS involvement......Page 334 Retinoblastoma......Page 335 Hodgkin’s lymphoma......Page 336 Wilms’ tumour......Page 337 Pelvic irradiation......Page 338 Conclusion......Page 339 References......Page 340 Acute reactions in healthy tissue......Page 341 Skin......Page 342 Mouth......Page 348 Promotion of nutritional intake......Page 351 Pain control......Page 352 Small intestine......Page 353 Bone marrow......Page 354 Fatigue......Page 355 Brain......Page 356 Cystitis......Page 357 References......Page 358 The decision to use radiotherapy in the palliative care of children......Page 363 Radiotherapy in oncological emergencies......Page 364 Radiotherapy in end of life symptom management......Page 366 References......Page 368 Part 5 Late Effect of Cancer Therapies......Page 371 23. Overview of Long-Term Follow-Up......Page 373 The nursing role......Page 374 References......Page 375 Endocrinopathies......Page 377 Thyroid gland......Page 378 Hypothalamic pituitary axis......Page 379 Gonadal dysfunction......Page 380 Fertility......Page 383 Liver......Page 385 Neurological impairment......Page 386 Neuropsychological......Page 388 Eyes......Page 389 Craniofacial and dental......Page 390 Musculoskeletal......Page 391 Hearing......Page 393 Gastrointestinal......Page 394 Cardiac......Page 395 Renal and bladder......Page 396 Pulmonary......Page 397 Second malignancies......Page 398 References......Page 399 Assessment, planning, implementation and evaluation of programmes of care......Page 403 Liaison and education......Page 404 Provision and facilitation of alternative models of care......Page 405 Research and audit......Page 406 References......Page 407 26. Health Promotion for Long-Term Follow-Up Patients......Page 409 Smoking......Page 410 Nutrition, physical activity and achieving a healthy weight......Page 411 Sexual health......Page 413 Theoretical approaches and models......Page 414 References......Page 415 Defining quality of life in the health-care setting?......Page 417 Psychological function......Page 418 Social function......Page 419 Employment and insurance......Page 420 Conclusion......Page 421 References......Page 422 Index......Page 425 Much has changed since the first book Paediatric Oncology: Acute Nursing Care (1999), therefore, this new edition encompasses these changes in relation to the practice itself and the evidence that underpins it.В Emphasis is placed on ensuring terminology is accurate, in keeping with the language of the current day.В The book is divided into six sections: Chemotherapy, Haematopoetic Stem Cell Transplantation, General Surgery, Radiotherapy, Late Effects of cancer therapies, and Palliative Care.В There is a brief commentary at the end of each section/chapter by a ‘noviceвЂTM author but experienced practitioner, highlighting to the reader what is already known and what the section/chapter adds to their current knowledge and practice.

Much has changed since the first book Paediatric Oncology: Acute Nursing Care (1999), therefore, this new edition encompasses these changes in relation to the practice itself and the evidence that underpins it. Emphasis is placed on ensuring terminology is accurate, in keeping with the language of the current day.

The book is divided into six sections: Chemotherapy, Haematopoetic Stem Cell Transplantation, General Surgery, Radiotherapy, Late Effects of cancer therapies, and Palliative Care. There is a brief commentary at the end of each section/chapter by a 'novice' author but experienced practitioner, highlighting to the reader what is already known and what the section/chapter adds to their current knowledge and practice.

Much has changed since the first book Paediatric Oncology: Acute Nursing Care (1999), therefore, this new edition encompasses these changes in relation to the practice itself and the evidence that underpins it. Emphasis is placed on ensuring terminology is accurate, in keeping with the language of the current day. The book is divided into six sections: Chemotherapy, Haematopoetic Stem Cell Transplantation, General Surgery, Radiotherapy, Late Effects of cancer therapies, and Palliative Care. There is a brief commentary at the end of each section/chapter by a 'novice' author but experienced practitioner, highlighting to the reader what is already known and what the section/chapter adds to their current knowledge and practice