Cancer Complicating Pregnancy, An Issue of Obstetrics and Gynecology Clinics (Volume 32-4) (The Clinics: Internal Medicine, Volume 32-4)

Univ. of New Mexico, Albuquerque. Text reviews the known literature on diagnosis and management of cancer during pregnancy. Topics include cervical neoplasia, breast cancer, malignant adnexal masses, malignant melanoma, hematologic malignancies, and more. For clinicians. Cover......Page 1 Foreword......Page 2 Preface......Page 4 Cervical Neoplasia Complicating Pregnancy......Page 6 Human papillomavirus infection in pregnancy......Page 7 Managing the abnormal Pap smear in pregnancy......Page 8 Performing colposcopy in the pregnant patient......Page 9 Management of cervical dysplasia in pregnancy......Page 11 Diagnosis and management of invasive cervix cancer......Page 12 Effects of pregnancy after cervical cancer treatment......Page 15 References......Page 16 Breast Cancer and Pregnancy......Page 20 Physiology and anatomy......Page 21 Receptors and mechanisms of tumorigenesis......Page 22 Diagnosis......Page 24 Staging......Page 25 Treatment......Page 26 Prognosis......Page 27 References......Page 28 Malignant Melanoma in Pregnancy......Page 32 Incidence rates......Page 33 Reported associations between exogenous hormone use and melanoma......Page 34 Risk of maternal melanoma during pregnancy......Page 35 Pregnancy and maternal prognosis from melanoma......Page 36 References......Page 38 Epidemiology......Page 42 Pathologic types......Page 43 Treatment......Page 44 Special considerations......Page 45 Treatment......Page 46 Presentation......Page 47 Invasive mucinous tumors......Page 48 Treatment......Page 49 Treatment......Page 51 Special considerations......Page 52 Sertoli-Leydig cell tumors......Page 53 Treatment......Page 54 Carcinosarcoma of the ovary during pregnancy......Page 55 Metastatic tumors to the ovary during pregnancy......Page 56 Treatment......Page 57 References......Page 58 Hematologic Malignancies in Pregnancy......Page 67 Hodgkin's lymphoma......Page 68 Vignette 2: non-Hodgkin's lymphoma......Page 72 Non-Hodgkin's lymphoma......Page 73 Vignette 3: leukemia......Page 76 Leukemia......Page 77 Summary......Page 82 References......Page 83 Gestation Trophoblastic Diseases: Management of Cases with Persistent Low Human Chorionic Gonadotropin Results......Page 87 False-positive human chorionic gonadotropin......Page 91 Quiescent gestational trophoblastic disease......Page 93 Pituitary human chorionic gonadotropin......Page 95 Summary......Page 96 References......Page 97 Chemotherapeutic Drugs in Pregnancy......Page 99 Fetal risks......Page 100 Counseling for pregnancy and breastfeeding......Page 101 Alkylating agents......Page 102 Antimetabolites......Page 105 Nucleoside analogues......Page 106 Topoisomerase Ii inhibitors......Page 107 Vinca alkaloids......Page 108 Taxanes......Page 109 References......Page 110 Incidence......Page 113 Presentation......Page 114 Sigmoidoscopy and colonoscopy......Page 115 Pathologic stage......Page 116 Chemotherapy......Page 117 Maternal prognosis......Page 118 Incidence......Page 119 Presentation......Page 120 Surgery......Page 121 Prognosis......Page 122 Diagnosis......Page 123 Prognosis......Page 124 Diagnosis......Page 125 Risk factors......Page 126 Prognosis......Page 127 References......Page 128 Pathology of molar subtypes......Page 133 Choriocarcinoma and placental site trophoblastic tumor......Page 136 Initial clinical management......Page 139 Staging systems for gestational trophoblastic neoplasia......Page 140 Low-risk gestational trophoblastic neoplasia......Page 143 High risk gestational trophoblastic neoplasia......Page 144 Risk factors for developing molar pregnancy and implications for future pregnancies......Page 146 Hydatidiform mole coexisting with a twin live fetus......Page 147 Summary......Page 149 References......Page 150