Cancer Biomarkers in Body Fluids : Biomarkers in Circulation

This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry. /div Front Matter....Pages i-xix Melanoma Biomarkers in Circulation....Pages 1-39 Head and Neck Cancer Biomarkers in Circulation....Pages 41-69 Lung Cancer Biomarkers in Circulation....Pages 71-108 Breast Cancer Biomarkers in Circulation....Pages 109-145 Esophageal Cancer Biomarkers in Circulation....Pages 147-178 Gastric Cancer Biomarkers in Circulation....Pages 179-212 Colorectal Cancer Biomarkers in Circulation....Pages 213-246 Hepatocellular Carcinoma Biomarkers in Circulation....Pages 247-271 Pancreatic Cancer Biomarkers in Circulation....Pages 273-302 Renal Cell Carcinoma Biomarkers in Circulation....Pages 303-324 Urothelial Bladder Cancer Biomarkers in Circulation....Pages 325-338 Prostate Cancer Biomarkers in Circulation....Pages 339-369 Ovarian Cancer Biomarkers in Circulation....Pages 371-398 Endometriosis Biomarkers in Body Fluids....Pages 399-416 Endometrial Cancer Biomarkers in Circulation....Pages 417-433 Cervical Cancer Biomarkers in Circulation....Pages 435-456 Endocrine Cancer Biomarkers in Circulation....Pages 457-480 Brain Tumor Biomarkers in Circulation....Pages 481-497 Back Matter....Pages 499-509