Campylobacter Pylori : Proceedings of the First International Symposium on Campylobacter Pylori, Kronberg, June 12–13th, 1987

Campy/o/meler pylori was described for the first time in 1983. Up to now more than 100 papers have been published dealing with its microbiological properties and its clinical implications. The lime has come to survey the field, to evaluate the hith­ erto accumulated information, and 10 discuss the questions thai should be answered in the ruture. It was for these purposes that the First International Symposium on Campy/abaeter pylori was held. bringing together specialists from a variety of discipl ines, including basic scientists as well as clinicians. This book is based on papers given at the symposium. We are very grateful 10 Rohm-Pharma for undertaking to sponsor this meeting, and to Mrs. C. 1. Klein and her starr for the impeccable organisation which permillcd us to work in such a pleasant environment, In the interest of rapidity of publication, we have reduced the amount of editing to a minimum and have not, in any sense, "re­ fereed" the discussions, which were written by the contributors at the time of the question-and-answer session. They were also veiled by their authors at the proof stage, and we have done our best to retain their original spontaneous flavour. We hope, in this way. 10 have produced a satisfactory record of the events and an up-Io-dale overview of research on Campylobacrer pylori. Front Matter....Pages I-XIV Front Matter....Pages 1-1 Morphological and Biochemical Characterization of Campylobacter pylori ....Pages 3-16 Discussion....Pages 17-18 Protein Antigens of Campylobacter pylori : The Problem of Species Specificity....Pages 19-26 Discussion....Pages 27-28 Differences Between in Vitro and in Vivo Sensitivity of Campylobacter pylori to Antibacterials....Pages 29-36 Discussion....Pages 37-39 In Search of Animal Models for Campylobacter pylori Induced Disease....Pages 40-45 Discussion....Pages 46-46 An Animal Model of Gastritis Induced by Campylobacter pylori ....Pages 47-54 Discussion....Pages 55-56 Front Matter....Pages 57-57 Current Theories on Pathogenesis of Peptic Ulcer Disease....Pages 59-65 Discussion....Pages 66-68 The Mucus Bicarbonate Barrier and Its Role in Gastroduodenal Mucosal Protection....Pages 69-75 Discussion....Pages 76-77 Semiquantitative Histopathology of Active Chronic Gastritis in Campylobacter pylori Infection and Its Relationship to Peptic Ulcer Disease and Gastric Carcinoma....Pages 78-87 Discussion....Pages 88-91 Front Matter....Pages 93-93 Incidence of Campylobacter pylori in Patients with Gastritis and Peptic Ulcer Disease in Various Countries....Pages 95-102 Discussion....Pages 103-105 Molecular Epidemiology and Natural History of Campylobacter pylori Colonization....Pages 106-107 Discussion....Pages 108-109 Front Matter....Pages 93-93 Campylobacter pylori in Children....Pages 110-115 Discussion....Pages 116-117 Front Matter....Pages 119-119 Monoclonal Antibodies Against Campylobacter pylori ....Pages 121-126 Production and Characterization of Monoclonal Antibodies Against Campylobacter pylori ....Pages 127-132 Discussion....Pages 133-134 Rapid Identification of Campylobacter pylori in Gastric Biopsies....Pages 135-141 Discussion....Pages 142-144 Comparison Between Cultural and Histological Techniques in Diagnosis of Campylobacter pylori Colonization....Pages 145-148 Discussion....Pages 149-150 Experience with 14 C-Urea Breath Test in Detecting Campylobacter pylori ....Pages 151-153 Discussion....Pages 154-156 Systemic Immune Responses to Campylobacter pylori Colonization....Pages 157-163 Local Immune Responses to Campylobacter pylori Colonisation....Pages 164-167 Discussion....Pages 168-170 Front Matter....Pages 171-171 Therapeutic Strategies in Medical Management of Peptic Ulcer Disease....Pages 173-180 Discussion....Pages 181-183 Gastroprotective and Ulcer Healing Properties of Bismuth Salts....Pages 184-192 Discussion....Pages 193-194 Treatment of Peptic Ulcer Disease with Bismuth Preparations....Pages 195-203 Discussion....Pages 204-205 Front Matter....Pages 171-171 Treatment of Campylobacter Gastritis with Bismuth Salts....Pages 206-211 Discussion....Pages 212-214 Attempts to Eradicate Campylobacter pylori — Dutch Experiences....Pages 215-218 Discussion....Pages 219-219 Attempts to Eradicate Campylobacter pylori — Irish Experiences....Pages 220-224 Discussion....Pages 225-227 Attempts to Eradicate Campylobacter pylori — German Experiences....Pages 228-230 Discussion....Pages 231-232 Front Matter....Pages 233-233 Campylobacter pylori : Addressing the Controversies....Pages 235-242 Discussion....Pages 243-245 Back Matter....Pages 247-249 This is the first book to deal exclusively with the newly described bacterium Campylobacter pylori. It reflects the knowledge accumulated until now in the field and covers: the microbiology and biochemistry of Campylobacter pylori; the pathophysiology of gastritis and peptic ulcer disease; the epidemiology of Campylobacter pylori infection; the diagnosis of Campylobacter pylori infection; and the treatment of chronic gastritis and peptic ulcers with bismuth salts. Readers are therefore offered an up-to-date survey of the latest scientific results on this new topic