BSAVA Manual of Canine and Feline Endocrinology, 4th Edition

Over recent years several endocrine disorders, such as feline acromegaly and hyperaldosteronism, have become of greater importance and a range of new therapies have emerged that are now considered routine. This new edition has been comprehensively updated, while retaining the emphasis on the common problems encountered in investigating and treating endocrine diseases. Unlike the previous editions, the Manual is divided into sections covering each endocrine gland as this is more traditionally used by endocrinologists. These sections cover the major and minor endocrine disorders of each species. A separate section deals with relevant presenting complaints in a problem oriented manner. This fourth edition provides a ready source of practical information for veterinary surgeons in general practice and will also be useful for undergraduate veterinary students, veterinary nurses and veterinary graduates embarking on further qualifications in small animal medicine. The international range of renowned contributors reflects the current globalization of tests and treatments for endocrine disease. Contents 4 Contributors 6 Foreword 9 Preface 10 Hormone assays and collection of samples 12 Principles of interpreting endocrine test results 19 Disorders of vasopressin production 26 Pituitary dwarfism 39 Acromegaly 46 Hyperparathyroidism 54 Hypoparathyroidism 67 Canine hypothyroidism 74 Canine hyperthyroidism 97 Feline hyperthyroidism 103 Feline hypothyroidism 122 Canine diabetes mellitus 127 Feline diabetes mellitus 144 Insulinoma and other gastrointestinal tract tumours 159 Canine hypoadrenocorticism 167 Canine hyperadrenocorticism 178 Feline hyperadrenocorticism 201 Feline hypoadrenocorticism 210 Feline hyperaldosteronism 215 Investigation of polyuria and polydipsia 226 Investigation of hypercalcaemia and hypocalcaemia 232 Investigation of unstable canine diabetes mellitus 245 Investigation of unstable feline diabetes mellitus 254 Ketoacidosis 262 Investigation of hypoglycaemia 270 Investigation of symmetrical alopecia in dogs 276 Investigation of adrenal masses 283 Investigation of hyperlipidaemia 289 Index 295 Since publication of the third edition in 2004 there have been many significant advances. Several endocrine disorders, such as feline acromegaly and hyperaldosteronism, have risen in importance. The use of diet and novel insulins in diabetic cats, and new drugs such as trilostane and methimazole, which are briefly mentioned in previous editions, are now considered routine. In addition, the genetic risks associated with many disorders have been elucidated. •A new chapter presents the principles of interpreting endocrine test results and discusses how test performance can be assessed to help improve diagnostic confidence. •The central section on glands and their diseases is presented in a standard format to aid information retrieval - detailing physiology, aetiology, clinical features, diagnosis and treatment. •The final section has been rewritten to focus on solving clinical and clinicopathological abnormalities with an endocrine dimension. This completely revised and updated edition provides a practical, clinically oriented approach with the most up-to-date information. Revolutionary advances in endocrinology are discussed in depth