Brain and human body modeling 2020 : computational human models presented at EMBC 2019 and the BRAIN Initiative® 2019 Meeting

This open access book describes modern applications of computational human modeling in an effort to advance neurology, cancer treatment, and radio-frequency studies including regulatory, safety, and wireless communication fields. Readers working on any application that may expose human subjects to electromagnetic radiation will benefit from this book’s coverage of the latest models and techniques available to assess a given technology’s safety and efficacy in a timely and efficient manner. * Describes computational human body phantom construction and application; * Explains new practices in computational human body modeling for electromagnetic safety and exposure evaluations; * Includes a survey of modern applications for which computational human phantoms are critical. Front Matter ....Pages i-xi Front Matter ....Pages 1-1 Tumor-Treating Fields at EMBC 2019: A Roadmap to Developing a Framework for TTFields Dosimetry and Treatment Planning (Ze’ev Bomzon, Cornelia Wenger, Martin Proescholdt, Suyash Mohan)....Pages 3-17 How Do Tumor-Treating Fields Work? (Kristen W. Carlson, Jack A. Tuszynski, Socrates Dokos, Nirmal Paudel, Thomas Dreeben, Ze’ev Bomzon)....Pages 19-35 A Thermal Study of Tumor-Treating Fields for Glioblastoma Therapy (Nichal Gentilal, Ricardo Salvador, Pedro Cavaleiro Miranda)....Pages 37-62 Improving Tumor-Treating Fields with Skull Remodeling Surgery, Surgery Planning, and Treatment Evaluation with Finite Element Methods (Nikola Mikic, Anders R. Korshoej)....Pages 63-77 Front Matter ....Pages 79-79 A Computational Parcellated Brain Model for Electric Field Analysis in Transcranial Direct Current Stimulation (M. A. Callejón-Leblic, Pedro C. Miranda)....Pages 81-99 Computational Models of Brain Stimulation with Tractography Analysis (Stefanie Riel, Mohammad Bashiri, Werner Hemmert, Siwei Bai)....Pages 101-117 Personalization of Multi-electrode Setups in tCS/tES: Methods and Advantages (R. Salvador, M. C. Biagi, O. Puonti, M. Splittgerber, V. Moliadze, M. Siniatchkin et al.)....Pages 119-135 Front Matter ....Pages 137-137 Modelling Studies of Non-invasive Electric and Magnetic Stimulation of the Spinal Cord (Sofia Rita Fernandes, Ricardo Salvador, Mamede de Carvalho, Pedro Cavaleiro Miranda)....Pages 139-165 A Miniaturized Ultra-Focal Magnetic Stimulator and Its Preliminary Application to the Peripheral Nervous System (Micol Colella, Micaela Liberti, Francesca Apollonio, Giorgio Bonmassar)....Pages 167-176 Front Matter ....Pages 177-177 Combining Noninvasive Electromagnetic and Hemodynamic Measures of Human Brain Activity (Fa-Hsuan Lin, Thomas Witzel, Matti S. Hämäläinen, Aapo Nummenmaa)....Pages 179-193 Multiscale Modeling of EEG/MEG Response of a Compact Cluster of Tightly Spaced Pyramidal Neocortical Neurons (Sergey N. Makarov, Jyrki Ahveninen, Matti Hämäläinen, Yoshio Okada, Gregory M. Noetscher, Aapo Nummenmaa)....Pages 195-211 Front Matter ....Pages 231-231 Robustness in Neural Circuits (Jeffrey E. Arle, Longzhi Mei, Kristen W. Carlson)....Pages 213-229 Insights from Computational Modelling: Selective Stimulation of Retinal Ganglion Cells (Tianruo Guo, David Tsai, Siwei Bai, Mohit Shivdasani, Madhuvanthi Muralidharan, Liming Li et al.)....Pages 233-247 Functional Requirements of Small- and Large-Scale Neural Circuitry Connectome Models (Kristen W. Carlson, Jay L. Shils, Longzhi Mei, Jeffrey E. Arle)....Pages 249-260 Front Matter ....Pages 271-271 Simplifying the Numerical Human Model with k-means Clustering Method (Kyoko Fujimoto, Leonardo M. Angelone, Sunder S. Rajan, Maria Ida Iacono)....Pages 261-270 Using Anatomical Human Body Model for FEM SAR Simulation of a 3T MRI System (Alexander Prokop, Tilmann Wittig, Abhay Morey)....Pages 273-281 RF-Induced Unintended Stimulation for Implantable Medical Devices in MRI (James E. Brown, Rui Qiang, Paul J. Stadnik, Larry J. Stotts, Jeffrey A. Von Arx)....Pages 283-292 Estimating Electric Field and SAR in Tissue in the Proximity of RF Coils (Rosti Lemdiasov, Arun Venkatasubramanian, Ranga Jegadeesan)....Pages 293-307 The CAD-Compatible VHP-Male Computational Phantom (Gregory M. Noetscher)....Pages 309-323 Front Matter ....Pages 345-345 Preprocessing General Head Models for BEM-FMM Modeling Pertinent to Brain Stimulation (William A. Wartman)....Pages 325-343 Profiling General-Purpose Fast Multipole Method (FMM) Using Human Head Topology (Dung Ngoc Pham)....Pages 347-381 Analytical Solution for the Electric Field Response Generated by a Nonconducting Ellipsoid (Prolate Spheroid) in a Conducting Fluid Subject to an External Electric Field (Andrey B. Yakovlev, Valeriya S. Federyaeva)....Pages 383-389 Example of Steady-State Electric-Current Modeling of a Complicated Cellular Topology with Boundary Element Fast Multipole Method (Vishwanath Iyer, William A. Wartman, Aapo Nummenmaa, Sergey N. Makarov)....Pages 391-396 Correction to: Brain and Human Body Modeling 2020 (Sergey N. Makarov, Gregory M. Noetscher, Aapo Nummenmaa)....Pages C1-C1 Back Matter ....Pages 397-407