Botulinum Toxin in Painful Diseases (Pain and Headache, Vol. 14)

The exceptionally successful history of botulinum toxin and its likely future has hardly an equivalent. Initially, it was used in strabismus, blepharospasm and hemifacial spasm, later also in focal dystonia and spasticity and it has been shown to effectively treat wrinkles, hyperhidrosis and a great number of ensuing indications. By treating symptoms or disorders associated with pain, its analgesic effect was first noticed. The efficacy and reasons for this side effect have since been investigated and a number of models explaining the mode of action have been presented. However, even if we know that botulinum toxin undoubtedly helps in certain pain syndromes, there is still much work to do to identify the major ones, define the optimum dose and the preferred site of injection. Indicating current positions and kindling the growing interest in this extraordinary therapeutic agent this book presents a timely overview on pain management with botulinum toxin. Thus, it will be of great interest especially for anesthesiologists and neurologists in their clinical work and medical research. Cover......Page 1 Preliminary Pages.pdf......Page 2 01 Pharmacology of Botulinum Neurotoxins.pdf......Page 9 02 Botulinum Toxin A in Pain Management- Mechanisms of Action and Rationale for Optimum Use.pdf......Page 22 03 Myofascial Pain Syndrome.pdf......Page 31 04 Type A Botulinum Toxin in Myofascial Facial Pain and Dysfunction.pdf......Page 50 05 Pain in Cervical Dystonia.pdf......Page 62 06 Treatment of Painful Dystonia with Botulinum Toxin.pdf......Page 79 07 Botulinum Toxin in Tension-Type Headache.pdf......Page 90 08 Botulinum Toxin in the Treatment of Migraine.pdf......Page 110 09 Treatment of Spasticity-Related Pain Syndromes.pdf......Page 134 10 Treatment of Piriformis Syndrome with Botulinum Toxin.pdf......Page 148 11 Botulinum Toxin in Low Back Pain.pdf......Page 167 Subject Index.pdf......Page 178 This book presents an overview of pain management with botulinum toxin, of interest especially to anesthesiologists and neurologists. After introductory chapters on the pharmacology of botulinum neurotoxins and their mechanisms of action and rationale for use in pain management, applications are described in areas such as myofascial pain syndrome, cervical dystonia, migraine and tension headache, spasticity-related pain syndromes, and low back pain. Annotation (c)2003 Book News, Inc., Portland, OR