Blood Oxygenation : Proceedings of the International Symposium on Blood Oxygenation, Held at the University of Cincinnati, December 1–3, 1969

Under the broad heading of blood oxygenation there may be specific areas of study, such as the kinetics of the oxygen­ hemoglobin reaction, diffusion of gases through the red cell, blood preservation, blood chemistry, oxygen electrode design and the design and evaluation of artificial blood oxygenators. ~lood oxygenation is of interest to many disciplines including physicians, chemists, physicists, biologists, physiologists and engineers. The International Symposium on Blood Oxygenation was or­ ganized in order to bring together the people working in the various areas of blood oxygenation. This multidiscipline meet­ ing was held at the University of Cincinnati on December 1, 2 and 3 of 1969. It was jOintly sponsored by the U. S. Army Medi­ cal Research and Development Command and the University of Cin­ cinnati. Participants came from Australia, England, Israel, Italy, Japan and the United States. There were 122 persons registered for the Symposium. From the nature of the discussion during the meeting, it seemed apparent that the participants were benefiting from the contacts with colleagues in other disciplines. The result was a significant contribution to the present fund of knowledge of blood oxygenation and an enhancement of the future work. Front Matter....Pages i-x Factors Determining the Velocity of Gas Uptake by Intracellular Hemoglobin....Pages 1-23 Oxygenation Velocity of the Red Cell and Pulmonary Diffusing Capacity....Pages 24-61 Membrane Resistance and Diffusion Coefficients: The Intact Red Cell....Pages 62-71 Models for Simultaneous Diffusion and Chemical Reaction of Oxygen within the Intact Red Cell of Whole Blood....Pages 72-106 In Vitro Measurement of Uncombined Oxygen Concentration in Intact Red Cells....Pages 107-115 The Interaction of Carbon Dioxide with the Rate of Exchange of Oxygen by Red Blood Cells....Pages 116-136 Physicochemical Properties of Blood Constituents Derived from Porphyrins....Pages 137-156 Equilibrium and Kinetic Aspects of the Reaction of Hemoglobin, Isolated Chains and Intermediates with Oxygen....Pages 157-174 A Mathematical Analysis Predicting Cerebral Tissue Reoxygenation Time as a Function of the Rate of Change of Effective Cerebral Blood Flow....Pages 175-200 Brain Tissue Oxygenation as Determined with a New Ultramicro Oxygen Electrode....Pages 201-217 A Distributed Parameter Mathematical Analysis of Oxygen Exchange from Maternal to Fetal Blood in the Human Placenta....Pages 218-221 The Effects of Inert Gases, Preservatives and Storage on Oxygen Transport in Blood....Pages 222-230 The Control of Hemoglobin Function in Blood Stored for Transfusion Purposes....Pages 231-242 Effect of Plasma Constituents on Oxygen Diffusivity....Pages 243-261 Internal Viscosity of the Red Blood Cell and the Capillary Inversion Phenomena as Factors in Oxygen Transport....Pages 262-275 The Oxygenation of Blood in Artificial Membrane Devices....Pages 276-305 Design Considerations and Long-Term in Vivo Studies with the Disposable Spiral Membrane Lung....Pages 306-320 A Mathematical Model for the Prediction of Oxygen, Carbon Dioxide, and pH Profiles with Augmented Diffusion in Capillary Blood Oxygenators....Pages 321-333 Development of Capillary Membrane Blood Oxygenators....Pages 334-354 Oxygenation of Blood for Clinical Applications....Pages 355-372 Back Matter....Pages 373-374