Biopsy of Bone in Internal Medicine: An Atlas and Sourcebook (Current Histopathology, 21)

This comprehensive book, lavishly illustrated with over 700 colour pictures, addresses the subject of bone in internal medicine. It is based on biopsies of bone and first describes the normal range of physiological findings in iliac crest biopsies in young, middle-aged and elderly individuals. The book then deals systematically with the osseous disorders most frequently encountered in internal medicine, and some that would be considered in the differential diagnosis. Numerous up-to-date references are included. The clinical applications of biopsies of bone are emphasized as well as their clinical interpretation; sections on histomorphometry and functional aspects of bone cells are also included. The book will be of particular interest to specialists in internal medicine, endocrinology, nephrology, haematology and oncology, as well as being a bench manual for the practising pathologist. Front Matter....Pages 1-7 Introduction and aims....Pages 8-8 Normal bone....Pages 9-48 Bone biopsy....Pages 49-60 Histomorphometry....Pages 61-64 Principles of bone biopsy pathology....Pages 65-70 Ageing and bone structure....Pages 71-74 Inflammations in bone....Pages 75-87 Necrosis, grafts and healing in bone....Pages 88-97 Osteoporosis....Pages 98-115 Osteogenesis imperfecta....Pages 116-120 Osteosclerosis....Pages 121-129 Osteomalacia....Pages 130-136 Primary hyperparathyroidism....Pages 137-147 Renal bone disease....Pages 148-155 Paget’s disease of bone....Pages 156-163 Miscellaneous bone diseases....Pages 164-176 Systemic mastocytosis....Pages 177-186 Osteomyelosclerosis....Pages 187-193 Multiple myeloma....Pages 194-206 Leukaemias and lymphomas in bone....Pages 207-215 Metastatic bone disease....Pages 216-232 Back Matter....Pages 233-238