Biomedical Sensors and Measurement (Advanced Topics in Science and Technology in China)

"Biomedical Sensors and Measurement" is an interdisciplinary book combining electronics with biology and medicine. It gives an overview of the concept and principle of biomedical sensors and measurement. First, the basic theory and technology are explained, followed by details of the physical sensors, chemical sensors, biosensors and their typical applications in biomedicine. Furthermore, the interface technology of the sensors and the typical measurement systems is presented. The large amount of vivid and specific figures and formulas will help to deepen the understanding of the fundamental and new applications involving biomedical sensors and measurement technology. The book is intended for biomedical engineers, medical physicists and other researchers and professionals in biomedicine-related specialties, especially interdisciplinary studies. Prof. Ping Wang and Dr. Qingjun Liu both work at the Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, China. Contents......Page 13 1.1.1 Basic Concept of Sensors......Page 17 1.1.2 Classification of Biomedical Sensors......Page 18 1.2.1 Bioelectrical Signal Detection......Page 19 1.2.3 Other Physiological and Biochemical Parameter Detection......Page 20 1.3 Characteristics of Biomedical Sensors and Measurement......Page 21 1.3.1 Features of Biomedical Sensors and Measurement......Page 22 1.3.2 Special Requirement of Biomedical Sensors and Measurement......Page 23 1.4.1 Invasive and Non-invasive Detection......Page 24 1.4.2 Multi-parameters Detection......Page 25 1.4.3 In vitro and in vivo Detection......Page 26 1.4.4 Intelligent Artificial Viscera......Page 27 1.4.5 Micro-nano Systems......Page 28 1.4.6 Biochips and Microfluidics......Page 29 References......Page 30 2.1 Introduction......Page 33 2.2.1 Static Characteristics......Page 34 2.2.2 Dynamic Characteristics......Page 37 2.3.1 Measurement Methods......Page 41 2.3.2 Sensor Measurement System......Page 42 2.3.3 Signal Modulation and Demodulation......Page 45 2.3.4 Improvement of Sensor Measurement System......Page 47 2.4.1 Concept and Principle of Biocompatibility......Page 49 2.4.2 Biocompatibility for Implantable Biomedical Sensors......Page 52 2.4.3 Biocompatibility for in vitro Biomedical Sensors......Page 54 2.5.1 Lithography......Page 58 2.5.2 Film Formation......Page 59 2.5.3 Etching......Page 60 2.5.4 Design of the Biomedical Sensors......Page 62 References......Page 64 3.1 Introduction......Page 67 3.2.1 Resistance Strain Sensors......Page 68 3.2.2 Piezoresistive Sensors......Page 75 3.3.1 Basics......Page 79 3.3.2 Applications in Biomedicine......Page 81 3.4.1 Principle and Configuration......Page 83 3.4.2 Measurement Circuits......Page 85 3.4.3 Biomedical Applications......Page 86 3.5 Piezoelectric Sensors and Measurement......Page 93 3.5.1 Piezoelectric Effect and Piezoelectric Materials......Page 94 3.5.2 Measurement Circuits......Page 97 3.5.3 Biomedical Applications......Page 98 3.6 Magnetoelectric Sensors and Measurement......Page 101 3.6.1 Magnetoelectric Induction Sensors......Page 102 3.6.2 Applications in Biomedcine......Page 105 3.6.3 Hall Magnetic Sensors......Page 106 3.7.1 Photoelectric Element......Page 111 3.7.2 Fiber Optic Sensors......Page 116 3.7.3 Applications of Photoelectric Sensors......Page 118 3.8.1 Thermosensitive Elements......Page 120 3.8.2 Thermocouple Sensors......Page 122 3.8.3 Integrated Temperature Sensors......Page 124 3.8.4 Applications in Biomedicine......Page 126 References......Page 128 4.1.1 History......Page 133 4.1.3 Classification and Characteristics......Page 135 4.2.1 Ion-Selective Electrodes......Page 137 4.2.2 Ion-Selective Field-Effect Transistors......Page 142 4.2.3 Light Addressable Potentiometric Sensors......Page 146 4.2.4 Microelectrode Array......Page 150 4.3.1 Electrochemical Gas Sensors......Page 154 4.3.2 Semiconductor Gas Sensors......Page 158 4.3.3 Solid Electrolyte Gas Sensors......Page 162 4.3.4 Surface Acoustic Wave Sensors......Page 166 4.4 Humidity Sensors......Page 169 4.4.1 Capacitive Humidity Sensors......Page 170 4.4.2 Resistive Humidity Sensors......Page 172 4.4.3 Thermal Conductivity Humidity Sensors......Page 174 4.5.1 e-Nose......Page 176 4.5.2 e-Tongue......Page 184 4.6.1 Design and Fabrication......Page 189 4.7 Sensor Networks......Page 199 4.7.1 History of Sensor Networks......Page 200 4.7.2 Essential Factors of Sensor Networks......Page 201 4.7.3 Buses of Sensor Networks......Page 202 4.7.4 Wireless Sensor Network......Page 204 References......Page 211 5.1.1 History and Concept of Biosensors......Page 215 5.1.2 Components of a Biosensor......Page 216 5.1.3 Properties of Biosensors......Page 218 5.1.4 Common Bioreceptor Components......Page 219 5.2.1 Enzyme Biosensors......Page 220 5.2.2 Microorganism Biosensors......Page 224 5.3.1 Antibody and Antigen Biosensors......Page 227 5.3.2 Nucleic Acid Biosensors......Page 235 5.3.3 Receptor and Ion Channel Biosensors......Page 240 5.4 Cell and Tissue Biosensors......Page 243 5.4.1 Cellular Metabolism Biosensors......Page 245 5.4.2 Cellular Impedance Biosensors......Page 248 5.4.3 Extracellular Potential Biosensors......Page 252 5.5.1 Chips of Microarray......Page 257 5.5.2 Gene and Protein Chips......Page 258 5.5.3 Tissue and Cell Chips......Page 264 5.5.4 Lab-on-a-Chip......Page 267 5.6.1 Nanomaterials for Biosensors......Page 269 5.6.2 Nanoparticles and Nanopores Biosensors......Page 271 5.6.3 Nanotubes and Nanowires Biosensors......Page 280 References......Page 288 Index......Page 293 This interdisciplinary book combines electronics with biology and medicine, providing an overview of biomedical sensors and measurement. The text describes the basic theory and technology, as well as the physical and chemical sensors, biosensors and their applications in biomedicine. Ping Wang, Qingjun Liu. Includes Bibliographical References And Index.