Biomaterials Engineering and Devices: Human Applications Vol. 1: Volume 1: Fundamentals and Vascular and Carrier Applications

The medical device industry faces critical ongoing challenges in the search for new and better materials for advanced medical applications and to replace old materials that no longer stand the test of time. In Biomaterials Engineering and Devices: Human Applications, Volume 1: Fundamentals and Vascular and Carrier Applications, authoritative international experts comprehensively review many current state-of-the-art uses of polymers, metals, and ceramics in the human body. A veritable encyclopedia of valuable data and experience, this volume not only fully addresses the major issues of compatibility and functionality, but also provides a technical treatise on the design and evaluation of biomaterials for vascular applications and on biomaterials as carriers for bioactive agents. The discussion includes treatment of emerging materials and of the regulatory and technical forces that shape their development. A second volume, Biomaterials Engineering and Devices: Human Applications, Volume 2 is devoted to biomaterials for dental applications, bony biomaterials for grafting applications, and orthopedic fixtures and cements. Extensively illustrated and referenced, Biomaterials Engineering and Devices: Human Applications, Volume 1: Fundamentals and Vascular and Carrier Applications integrates for today‚s bioengineering professionals the basic science, engineering, and practical medical experience needed to meet the ever-growing demand for new and better biomaterials. Front Matter....Pages i-xvi Front Matter....Pages 1-1 Molecular Mechanism of Biomaterial-Mediated Phagocyte Responses....Pages 3-14 Hypersensitivity Associated with Metallic Biomaterials....Pages 15-23 Blood-Compatible Bioactive Polymers....Pages 25-47 Novel Modification Method of Bioprosthetic Tissue for Improved Calcification Resistance....Pages 49-56 Biocompatibility of Silicone Gel Breast Implants....Pages 57-84 Endothelialization of Vascular Prostheses....Pages 85-118 Front Matter....Pages 119-119 Collagen-Based Vascular Prostheses....Pages 121-136 Surface Modifications of Mechanical Heart Valves....Pages 137-144 The Importance of Radial Forces in Vascular Stent Design....Pages 145-160 Blood Leak-Proof Porous Vascular Grafts....Pages 161-179 Formation of Neointima in Vascular Prosthesis Sealed with Autologous Adipose Tissue Fragments for Femoropopliteal Bypass....Pages 181-187 Clinical Improvement in Patients with Coronary and Peripheral Vascular Diseases Treated by LDL-Adsorption Using the Liposorber LA-15 System....Pages 189-200 Development of a New Hybrid Coronary Stent Design with Optimized Biocompatible Properties....Pages 201-222 Front Matter....Pages 223-223 Incorporation of Active Agent into Biodegradable Cement....Pages 225-237 New Synthetic Degradable Polymers as Carrier Materials for BMP....Pages 239-249 Use of Carrier Materials in Delivery of Bone Inductor Substances....Pages 251-265 Preclinical and Clinical Evaluation of Osteogenic Protein-1 (BMP-7) in Bony Sites....Pages 267-277 Enzyme-Based Artificial Liver Support....Pages 279-293 Bupivacaine Release from Biopolymeric Depots for the Alleviation of Postoperative Pain....Pages 295-306 Biomaterial Implants for Treatment of Central Nervous System Diseases....Pages 307-334 Back Matter....Pages 335-344 The medical device industry faces critical ongoing challenges in the search for new and better materials for advanced medical applications and to replace old materials that no longer stand the test of time. In Biomaterials Engineering and Devices: Human Applications, Volume 1: Fundamentals and Vascular and Carrier Applications, authoritative international experts comprehensively review many current state-of-the-art uses of polymers, metals, and ceramics in the human body. A veritable encyclopedia of valuable data and experience, this volume not only fully addresses the major issues of compatibility and functionality, but also provides a technical treatise on the design and evaluation of biomaterials for vascular applications and on biomaterials as carriers for bioactive agents. The discussion includes treatment of emerging materials and of the regulatory and technical forces that shape their development. A second volume, Biomaterials Engineering and Devices: Human Applications, Volume 2 is devoted to biomaterials for dental applications, bony biomaterials for grafting applications, and orthopedic fixtures and cements. Extensively illustrated and referenced, Biomaterials Engineering and Devices: Human Applications, Volume 1: Fundamentals and Vascular and Carrier Applications integrates for today, s bioengineering professionals the basic science, engineering, and practical medical experience needed to meet the ever-growing demand for new and better biomaterials

Authoritative international experts comprehensively review many current state-of-the-art uses of polymers, metals, and ceramics in the human body. A veritable encyclopedia of valuable data and experience, this volume not only fully addresses the major issues of compatibility and functionality, but also provides a technical treatise on the design and evaluation of biomaterials for vascular application and on biomaterials as carriers for bioactive agents. A second volume, Biomaterials Engineering and Devices: Human Applications, Volume 2 is devoted to biomaterials for dental applications, bony biomaterials for grafting applications, and orthopedic fixtures and cements. Extensively illustrated and referenced, Biomaterials Engineering and Devices: Human Applications, Volume 1: Fundamentals and Vascular and Carrier Applications integrates for today's bioengineering professionals the basic science, engineering, and practical medical experience needed to meet the ever-growing demand for new and better biomaterials.

This volume deals with critical issues concerning biocompatible materials - polymers, metals and other substances used in or on the human body. The focus of the topics range from biopolymers used in controlled release drug delivery systems to biopolymeric plates used in bone repair.