BIOMAT 2005 : proceedings of the International Symposium on Mathematical and Computational Biology, Rio de Janeiro, Brazil, 3-8 December 2005

this Volume Contains The Contributions Of The Keynote Speakers To The Biomat 2005 Symposium, As Well As A Collection Of Selected Papers By Pioneering Researchers. It Provides A Comprehensive Review Of The Mathematical Modeling Of Cancer Development, Alzheimer S Disease, Malaria, And Aneurysm Development. Various Models For The Immune System And Epidemiological Issues Are Analyzed And Reviewed. The Book Also Explores Protein Structure Prediction By Optimization And Combinatorial Techniques (steiner Trees). The Coverage Includes Bioinformatics Issues, Regulation Of Gene Expression, Evolution, Development, Dna And Array Modeling, And Small World Networks. Preface. Editorial board of the BIOMAT consortium -- Biological modeling. Modelling aspects of vascular cancer development / Philip K. Maini, Tomás Alarcón and Helen M. Byrne. Cellular automaton modelling of biological pattern formation / Andreas Deutsch. A mathematical analysis of cylindrical shaped aneurysms / Tor A. Kwembe, Shatondria N. Jones. On the origin of metazoans / Frederick W. Cummings. A software tool to model genetic regulatory networks: applications to segmental patterning in Drosophila / Filipa Alves, Rui Dilão. The mitochondrial Eve in an exponentially growing population and a critique to the out of Africa model for human evolution / Armando G. M. Neves, Carlos H. C. Moreira. A neurocomputational model of the role of cholesterol in the process of Alzheimer's disease / Gizelle K. Vianna ... [et al.]. Theoretical study of a biofilm life cycle: growth, nutrient depletion and detachment / Galileo Dominguez-Zacarías, Erick Luna, Jorge X. Velasco-Hernández. Optimal control of distributed systems applied to the problems of ambient pollution / Santina F. Arantes, Jaime E. M. Rivera -- Epidemiology and immunology. Modeling the in vivo dynamics of viral infections / Ruy M. Ribeiro. Short and long-term dynamics of childhood diseases on dynamic small-world networks / José Verdasca. Clonal expansion of cytotoxic T cell clones: the role of the immunoproteasome / Michal Or-Guil, Fabio Luciani, Jorge Carneiro. Modeling plague dynamics: endemic states, outbreaks and epidemic waves / Francisco A. B. Coutinho. The basic reproductive rate in the Malaria model / Ana Paula Wyse, Luiz Bevilacqua, Marat Rafikov. Epidemiological model with fast dispersion / Mariano R. Ricard, Celia T. González González, Rodney C. Bassanezi -- Protein structure. Structure prediction of alpha-helical proteins / Scott R. McAllister, Christodoulos A. Floudas. Quality and effectiveness of protein structure comparative models / Domenico Raimondo ... [et al.]. Steiner minimal trees, twist angles, and the protein folding problem / James MacGregor Smith. Steiner trees as intramolecular networks of the biomacromolecular structures / Rubem P. Mondaini -- Bioinformatics. Exploring chemical space with computers: Informatics challenges for AI and machine learning / Pierre Baldi. Optimization of between group analysis of gene expression disease class prediction / Florent Baty ... [et al]. On biclustering with features selection for microarray data sets / Panos M. Pardalos, Stanislav Busygin, Oleg Prokopyev. Simple and effective classifiers to model biological data / Rogério L. Salvini, Inês C. Dutra, Viviana A. Morelli Contains the contributions of the keynote speakers to the BIOMAT 2005 symposium, as well as a collection of selected papers by pioneering researchers. This work provides a comprehensive review of the mathematical modeling of cancer development, Alzheimer's disease, malaria, and aneurysm development.