Biomarkers in Cancer (Biomarkers in Disease: Methods, Discoveries and Applications)

In The Past Decade There Has Been A Major Sea Change In The Way Disease Is Diagnosed And Investigated Due To The Advent Of High Throughput Technologies, Such As Microarrays, Lab On A Chip, Proteomics, Genomics, Lipomics, Metabolomics Etc. These Advances Have Enabled The Discovery Of New And Novel Markers Of Disease Relating To Autoimmune Disorders, Cancers, Endocrine Diseases, Genetic Disorders, Sensory Damage, Intestinal Diseases Etc. In Many Instances These Developments Have Gone Hand In Hand With The Discovery Of Biomarkers Elucidated Via Traditional Or Conventional Methods, Such As Histopathology Or Clinical Biochemistry. Together With Microprocessor-based Data Analysis, Advanced Statistics And Bioinformatics These Markers Have Been Used To Identify Individuals With Active Disease Or Pathology As Well As Those Who Are Refractory Or Have Distinguishing Pathologies. New Analytical Methods That Have Been Used To Identify Markers Of Disease And Is Suggested That There May Be As Many As 40 Different Platforms. Unfortunately Techniques And Methods Have Not Been Readily Transferable To Other Disease States And Sometimes Diagnosis Still Relies On Single Analytes Rather Than A Cohort Of Markers. There Is Thus A Demand For A Comprehensive And Focused Evidenced-based Text And Scientific Literature That Addresses These Issues. Hence The Formulation Of Biomarkers In Disease. The Series Covers A Wide Number Of Areas Including For Example, Nutrition, Cancer, Endocrinology, Cardiology, Addictions, Immunology, Birth Defects, Genetics, And So On. The Chapters Are Written By National Or International Experts And Specialists. Edited By Victor R. Preedy, Vinood B. Patel. Front Matter....Pages i-xxviii Front Matter....Pages 1-1 Front Matter....Pages 3-30 Front Matter....Pages 31-51 Front Matter....Pages 53-71 Front Matter....Pages 73-105 Front Matter....Pages 107-133 Front Matter....Pages 135-165 Front Matter....Pages 167-178 Front Matter....Pages 179-201 Front Matter....Pages 203-231 Front Matter....Pages 233-250 Back Matter....Pages 251-251 ....Pages 253-272 The World Health Organisation have reported that each year on a global basis there are over 8 million deaths from cancer. Part of the overall package of healthcare related to cancer is the application of biomarkers. Biomarkers can be used not only to determine stages and effects of cancer, but also to aid treatments regimes.