Biology of Metabolism in Growing Animals: Biology of Growing Animals Series (Volume 3) (Biology of Growing Animals, Volume 3)

The book is intended to provide in-depth reviews of the recent advances in major areas of metabolism in growing domestic animals. The study of metabolism represents a nexus of biological phenomenon that integrates the impact of nutrition, physiology, endocrinology, immunology, biochemistry, and cell biology in an organism. The development of new methodological techniques and experimental approaches have provide scientists with a greater understanding of how key nutrients or substrates are metabolized at the cellular, organ, and whole animal level. This book presents contributions from leading scientists in nutrition and physiology that highlight important new developments in interorgan and tissue-specific metabolism of protein and amino acids, lipids and fatty acids, and carbohydrates in monogastric and runinant species. Authors will describe the impact of specific biochemical pathways and expression of critical enzymes, routes of nutrient or substrate input, and anatomical or structural influences on the rates of metabolism in a given tissue or cell type. Major substrates/ fuels for oxidative metabolism, key signaling pathways, and intracellular molecules that regulate the major metabolic processes will be described. Also included is how the metabolism of growing animals is influenced by ontogeny, stage of differentiation, and major changes in diet, or the environment. The concepts and specific findings in each area are discussed in the context of their impact on the nutrient requirements, growth, environmental impact, healt and well-being of animals. The book will be a useful reference for research scientists, teachers and students interested in and advanced understanding of metabolism in growing animals. The book is written by leading experts and highlights some of the most recent advances in the field of metabolism. It is a useful reference for researchers and advanced level graduate students in nutrition, physiology and animal science. Presents recent advances in the field of metabolism. Content: Edited by Page iii Copyright Page iv Keynotes Page v Stepan Pierzynowski Institutions Providing Patronage and Financial Support Page vi Preface Page vii D.G. Burrin, H.J. Mersmann Dedication Pages ix-x Contributors Pages xi-xii Chapter 1 Regulation of metabolism and growth during prenatal life Original Research Article Pages 3-34 A.W. Bell, P.L. Greenwood, R.A. Ehrhardt Chapter 2 Regulation of skeletal muscle protein metabolism in growing animals Original Research Article Pages 35-68 T.A. Davis, M.L. Fiorotto Chapter 3 Whole animal and tissue proteolysis in growing animals Original Research Article Pages 69-82 V.E. Baracos Chapter 4 Cytokine regulation of protein accretion in growing animals Original Research Article Pages 83-106 R.W. Johnson, J. Escobar Chapter 5 Amino acid metabolism in the small intestine: biochemical bases and nutritional significance Original Research Article Pages 107-126 G. Wu, D.A. Knabe, N.E. Flynn Chapter 6 Role of intestinal first-pass metabolism on whole-body amino acid requirements Original Research Article Pages 127-156 R.F.P. Bertolo, P.B. Pencharz, R.O. Ball Chapter 7 Splanchnic protein and amino acid metabolism in growing animals Original Research Article Pages 157-196 D.G. Burrin, B. Stoll Chapter 8 Nitrogen metabolism by splanchnic tissues of ruminants Original Research Article Pages 197-218 C.K. Reynolds Chapter 9 Hepatic fatty acid oxidation and ketogenesis in young pigs Original Research Article Pages 219-234 J. Odle, P. Lyvers-Peffer, X. Lin Chapter 10 Essential fatty acid metabolism during early development Original Research Article Pages 235-274 S.M. Innis Chapter 11 Development of white adipose tissue lipid metabolism Original Research Article Pages 275-302 H.J. Mersmann, S.B. Smith Chapter 12 Ontogeny and metabolism of brown adipose tissue in livestock species Original Research Article Pages 303-322 S.B. Smith, G.E. Carstens Chapter 13 Interorgan lipid and fatty acid metabolism in growing ruminants Original Research Article Pages 323-350 J.K. Drackley Chapter 14 Environmental and hormonal regulation of energy metabolism in early development of the pig Original Research Article Pages 351-374 P. Herpin, I. Louveau, M. Damon, J. Le Dividich Chapter 15 Hepatic gluconeogenesis in developing ruminants Original Research Article Pages 375-390 S.S. Donkin, H. Hammon Chapter 16 Energy metabolism in the developing rumen epithelium Original Research Article Pages 391-404 B.W. Jesse Chapter 17 Splanchnic carbohydrate and energy metabolism in growing ruminants Original Research Article Pages 405-432 N.B. Kristensen, G.B. Huntington, D.L. Harmon Chapter 18 Methodological approaches to metabolism research Original Research Article Pages 433-478 X. Guan, D.G. Burrin Index Pages 479-484 "This book presents contributions from leading scientists in nutrition and physiology that highlight important new developments in metabolism. The concepts and specific findings in each area are discussed in the context of their impact on the nutrient requirements, growth, environmental impact, health and well-being of animals. The book will be a useful reference for research scientists, teachers and students interested in an advanced understanding of metabolism in growing animals."--Jacket Presents contributions from leading scientists in nutrition and physiology that highlights developments in interorgan and tissue-specific metabolism of protein and amino acids, lipids and fatty acids, and carbohydrates in monogastric and runinant species.