Biology Of Amphibian Tumors (recent Results In Cancer Research)

New Orleans has a distinguished history as a center for medical and biological learning, a history shared by Tulane University, its School of Medicine, and its Bio­ logical and Medical Sciences departments. This background made it especially fitting that the University, in conjunction with the Cancer Association of Greater New Orleans, Inc. and the National Cancer Institute, should sponsor the "Symposium: Biology of Amphibian Tumors" held October 28, 29, 30, 1968. The University wishes to express its appreciation to the Cancer Association for its assistance in making the Symposium possible and to acknowledge the support made available through the Bio­ medical Sciences Support Grant program of the National Institutes of Health. As the title of this volume indicates, the Symposium yielded valuable results in the area of cancer research and it stands to stimulate further efforts in this most important field. Some notion of the impact of this symposium is suggested by the broad range of the 200 participants it attracted. They came not only from the breadth and length of the U.S., but from abroad, from France, England, Austria, and Italy. Front Matter....Pages i-xvii State of the Art: Lucké Renal Adenocarcinoma....Pages 1-25 Interrelations of the Populations of the Rana pipiens Complex....Pages 26-34 Spontaneous and Experimental Mutations in the Newt Pleurodeles waltlii Michah....Pages 35-42 Nucleo-Cortical Interactions During Amphibian Development....Pages 43-51 Mass Culture of Amphibian Cells: Methods and Observations Concerning Stability of Cell Type....Pages 52-81 Dependence of Tumor Formation in Frogs on Abnormal Nucleolar Function....Pages 82-100 Characteristics of Cell Lines from Haploid and Diploid Anuran Embryos....Pages 101-111 Species Identification of Poikilothermic Tissue Culture Cells....Pages 112-120 Amino Acid and Nucleoside Incorporation in Frog Kidney Cells: An Autoradiographic Study....Pages 121-129 Immunity and Tolerance in Amphibia....Pages 130-136 Immunologic Tolerance and Blood Cell Chimerism in Experimentally Produced Parabiotic Frogs....Pages 137-152 Immunogenetic and Developmental Aspects of Tissue Transplantation Immunity in Urodele Amphibians....Pages 153-168 Immunoglobulin and Complement Systems of Amphibian Serum....Pages 169-176 The Amphibian as a Key Step in the Evolution of Lymphoid Tissue and Diverse Immunoglobulin Classes....Pages 177-183 Some Morphological and Biological Characteristics of a Tumor of the Newt, Triturus cristatus Laur....Pages 184-194 Skin Carcinogenesis, Mammals Versus Amphibia....Pages 195-203 Plasmacytoma in a Rana pipiens ....Pages 204-214 Structures of Spontaneous and Transplanted Tumors in the Axolotl ( Siredon mexicanum )....Pages 215-219 Tumors of the Testis in the Mexican Axolotl ( Ambystoma , or Siredon, mexicanum) ....Pages 220-228 Simulated Transmission of Renal Tumors in Oocytes and Embryos of Rana pipiens ....Pages 229-239 Non-specific Transmission of the Lucké Tumor....Pages 240-253 Lucké Renal Adenocarcinoma: Epidemiological Aspects....Pages 254-260 Chromosome Studies of Primary Renal Carcinoma from Vermont Rana pipiens ....Pages 261-278 Studies on the Viral Etiology of the Renal Adenocarcinoma of Rana pipiens (Lucké Tumor)....Pages 279-295 Fine Structure Studies of Cytoplasmic Viruses Associated with Frog Tumors....Pages 296-309 Comparative Studies of Amphibian Cytoplasmic Virus Strains Isolated from the Leopard Frog, Bullfrog, and Newt....Pages 310-326 Tadpole Edema Virus: Pathogenesis and Growth Studies and Additional Sites of Virus Infected Bullfrog Tadpoles....Pages 327-336 Herpestype Virus Latency in the Lucké Tumor....Pages 337-347 Density Gradient Centrifugation Studies on the Herpes-Type Virus of the Lucké Tumor....Pages 348-357 Reactivity of Serum from Frogs and Other Species with a Herpesvirus Antigen Extracted from a Burkitt Lymphoma Cultured Cell Line....Pages 358-364 A Preliminary Report on the Serology of Lucké and Burkitt Herpes-type Viruses: A Shared Antigen....Pages 365-367 Possible Immunological Factors in Amphibian Lymphosarcoma Development....Pages 368-384 Organ Cultures of Normal and Neoplastic Amphibian Tissues....Pages 385-398 Acceptance and Regression of a Strain-specific Lymphosarcoma in Mexican Axolotls....Pages 399-408 Development of Biologically Defined Strains of Amphibians....Pages 409-418 Diseases in an Amphibian Colony....Pages 419-428 Some Comparative Morphological Aspects of Renal Neoplasms in Rana pipiens and of Lymphosarcomas in Amphibia....Pages 429-440 Immunological Approaches to the Study of Viral Antigens Associated with Neoplasms....Pages 441-444 Nucleic Acid Homology as Applied to Investigations on the Relationship of Viruses to Neoplastic Diseases....Pages 445-454 Viruses Associated with Burkitt’s Lymphoma....Pages 455-459 A Herpes Virus as a Cause of Marek’s Disease in Chickens....Pages 460-468 Studies on the Viral Etiology of Marek’s Disease of Fowl....Pages 469-477 Herpes Simplex Viruses and Human Cancer: Current Status of the Problem....Pages 478-481 Summary and Perspectives....Pages 482-484