Biology and Mechanics of Blood Flows: Part I: Biology (CRM Series in Mathematical Physics)

__Biology and Mechanics of Blood Flows__ presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. Part I of this two-volume sequence, __Biology__, addresses the nanoscopic and microscopic scales. The nanoscale corresponds to the scale of biochemical reaction cascades involved in cell adaptation to mechanical stresses among other stimuli. The microscale is the scale of stress-induced tissue remodeling associated with acute or chronic loadings. The cardiovascular system, like any physiological system, has a complicated three-dimensional structure and composition. Its time dependent behavior is regulated, and this complex system has many components. In this authoritative work, the author provides a survey of relevant cell components and processes, with detailed coverage of the electrical and mechanical behaviors of vascular cells, tissues, and organs. Because the behaviors of vascular cells and tissues are tightly coupled to the mechanics of flowing blood, the major features of blood flows and the Navier-Stokes equations of mass and momentum conservation are introduced at the conclusion of this volume. This book will appeal to any biologist, chemist, physicist, or applied mathematician with an interest in the functioning of the cardiovascular system.

biology And Mechanics Of Blood Flows Presents The Basic Knowledge And State-of-the-art Techniques Necessary To Carry Out Investigations Of The Cardiovascular System Using Modeling And Simulation. Part I Of This Two-volume Sequence, Biology, Addresses The Nanoscopic And Microscopic Scales. The Nanoscale Corresponds To The Scale Of Biochemical Reaction Cascades Involved In Cell Adaptation To Mechanical Stresses Among Other Stimuli. The Microscale Is The Scale Of Stress-induced Tissue Remodeling Associated With Acute Or Chronic Loadings. The Cardiovascular System, Like Any Physiological System, Has A Complicated Three-dimensional Structure And Composition. Its Time Dependent Behavior Is Regulated, And This Complex System Has Many Components. In This Authoritative Work, The Author Provides A Survey Of Relevant Cell Components And Processes, With Detailed Coverage Of The Electrical And Mechanical Behaviors Of Vascular Cells, Tissues, And Organs. Because The Behaviors Of Vascular Cells And Tissues Are Tightly Coupled To The Mechanics Of Flowing Blood, The Major Features Of Blood Flows And The Navier-stokes Equations Of Mass And Momentum Conservation Are Introduced At The Conclusion Of This Volume. This Book Will Appeal To Any Biologist, Chemist, Physicist, Or Applied Mathematician With An Interest In The Functioning Of The Cardiovascular System.

Front Matter....Pages I-XIX The Cell....Pages 7-56 Plasma Membrane and Cell Environment....Pages 57-91 Ion Carriers and Receptors....Pages 93-153 Signaling Pathways....Pages 155-233 Transport and Cell Motion....Pages 235-263 Blood....Pages 265-294 Heart Wall....Pages 295-358 Vessel Wall....Pages 359-393 Endothelium....Pages 395-433 Tissue Growth, Repair, and Remodeling....Pages 435-488 Back Matter....Pages 489-657 This authoritative work presents the basic knowledge and state-of-the-art techniques necessary to carry out investigations of the cardiovascular system using modeling and simulation. The book provides a survey of relevant cell components and processes, with detailed coverage of the electrical and mechanical behaviors of vascular cells, tissues, and organs. Biological and mechanical glossaries are provided. pt. 1. Biology pt. 2. Mechanics and medical aspects.