Biological and Bio-inspired Nanomaterials: Properties and Assembly Mechanisms (Advances in Experimental Medicine and Biology Book 1174)

This book summarizes naturally occurring and designed bio-inspired molecular building blocks assembled into nanoscale structures. It covers a fascinating array of biomimetic and bioinspired materials, including inorganic nanozymes, structures formed by DNA origami, a wide range of peptide and protein-based nanomaterials, as well as their applications in diagnostics and therapeutics. The book elucidates the mechanism of assembly of these materials and characterisation of their mechanical and physico-chemical properties which inspires readers not only to exploit the potential applications of nanomaterials, but also to understand their potential risks and benefits. It will be of interest to a broad audience of students and researchers spanning the disciplines of biology, chemistry, engineering, materials science, and physics. Front Matter ....Pages i-vi Dynamics and Control of Peptide Self-Assembly and Aggregation (Georg Meisl, Thomas C. T. Michaels, Paolo Arosio, Michele Vendruscolo, Christopher M. Dobson, Tuomas P. J. Knowles)....Pages 1-33 Peptide Self-Assembly and Its Modulation: Imaging on the Nanoscale (Lanlan Yu, Yanlian Yang, Chen Wang)....Pages 35-60 The Kinetics, Thermodynamics and Mechanisms of Short Aromatic Peptide Self-Assembly (Thomas O. Mason, Alexander K. Buell)....Pages 61-112 Bacterial Amyloids: Biogenesis and Biomaterials (Line Friis Bakmann Christensen, Nicholas Schafer, Adriana Wolf-Perez, Daniel Jhaf Madsen, Daniel E. Otzen)....Pages 113-159 Fungal Hydrophobins and Their Self-Assembly into Functional Nanomaterials (Victor Lo, Jennifer I-Chun Lai, Margaret Sunde)....Pages 161-185 Nanostructured, Self-Assembled Spider Silk Materials for Biomedical Applications (Martin Humenik, Kiran Pawar, Thomas Scheibel)....Pages 187-221 Protein Microgels from Amyloid Fibril Networks (Lianne W. Y. Roode, Ulyana Shimanovich, Si Wu, Sarah Perrett, Tuomas P. J. Knowles)....Pages 223-263 Protein Nanofibrils as Storage Forms of Peptide Drugs and Hormones (Reeba Susan Jacob, A. Anoop, Samir K. Maji)....Pages 265-290 Nanozymes: Biomedical Applications of Enzymatic Fe3O4 Nanoparticles from In Vitro to In Vivo (Lizeng Gao, Xiyun Yan)....Pages 291-312 Self-Assembly of Ferritin: Structure, Biological Function and Potential Applications in Nanotechnology (Soumyananda Chakraborti, Pinak Chakrabarti)....Pages 313-329 DNA Nanotechnology for Building Sensors, Nanopores and Ion-Channels (Kerstin Göpfrich, Ulrich F. Keyser)....Pages 331-370 Bio Mimicking of Extracellular Matrix (Moumita Ghosh, Michal Halperin-Sternfeld, Lihi Adler-Abramovich)....Pages 371-399 Bioinspired Engineering of Organ-on-Chip Devices (Li Wang, Zhongyu Li, Cong Xu, Jianhua Qin)....Pages 401-440