Bioinformatics For Biomedical Science And Clinical Applications (woodhead Publishing Series In Biomedicine)

Dr. King-Hao Liang provides biomedical researchers and students with a state-of-the-art assessment of the application of bioinformatics to biomedical science and clinical applications. Contemporary biomedical and clinical researches are constantly pushed forward by the rapid advancement of various high throughput technologies on all the DNA, RNA and protein levels. These technologies include, for example, the advanced genome sequencing technology, microarray, ChIP-Chip and mass spectrometry. They enable researchers to conduct investigations on human health and disease in a systematic, genome-wide scale. This item is in: Biomedicine > Bioinformatics, computing and life sciences Jacket image for Bioinformatics for biomedical science and clinical applications - Woodhead Publishing Bioinformatics for biomedical science and clinical applications Kung-Hao Liang, LinKo Medical Center, Chang Gung Memorial Hospital, Taiwan R.O.C. Woodhead Publishing Series in Biomedicine No. 20 - a coherent presentation of concepts, methodologies and practical tools that systematically lead to significant discoveries in the biomedical and clinical area - real examples of cutting edge discoveries - the introduction of study types and technologies for all the DNA, RNA and protein levels - an emphasis on systems biomedical science featuring the integration and interpretation of a heterogeneous source of information Contemporary biomedical and clinical research is undergoing constant development thanks to the rapid advancement of various high throughput technologies at the DNA, RNA and protein levels. These technologies can generate vast amounts of raw data, making bioinformatics methodologies essential in their use for basic biomedical and clinical applications. Bioinformatics for biomedical science and clinical applications demonstrates what these cutting-edge technologies can do and examines how to design an appropriate study, including how to deal with data and address specific clinical questions. The first two chapters consider Bioinformatics and analysis of the human genome. The subsequent three chapters cover the introduction of Transcriptomics, Proteomics and Systems biomedical science. The remaining chapters move on to critical developments, clinical information and conclude with domain knowledge and adaptivity Contemporary biomedical and clinical research is undergoing constant development thanks to the rapid advancement of various high throughput technologies at the DNA, RNA and protein levels. These technologies can generate vast amounts of raw data, making bioinformatics methodologies essential in their use for basic biomedical and clinical applications.

Bioinformatics for biomedical science and clinical applications demonstrates what these cutting-edge technologies can do and examines how to design an appropriate study, including how to deal with data and address specific clinical questions. The first two chapters consider Bioinformatics and analysis of the human genome. The subsequent three chapters cover the introduction of Transcriptomics, Proteomics and Systems biomedical science. The remaining chapters move on to critical developments, clinical information and conclude with domain knowledge and adaptivity.

• A coherent presentation of concepts, methodologies and practical tools that systematically lead to significant discoveries in the biomedical and clinical area
• Real examples of cutting edge discoveries
• The introduction of study types and technologies for all the DNA, RNA and protein levels

This volume provides biomedical researchers and students with a state-of-the-art assessment of the application of bioinformatics to biomedical science and clinical applications front-matter......Page 1 1......Page 17 2......Page 25 3......Page 65 4......Page 99 5......Page 123 6......Page 145 7......Page 163 back-matter......Page 167