Biochemistry of Lipids, Lipoproteins and Membranes (Volume 31) (New Comprehensive Biochemistry, Volume 31)

This is the third edition of this advanced textbook, written with two major objectives in mind. One is to provide an advanced textbook covering the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, and molecular biology. The second objective is to provide a clear summary of these research areas for scientists presently working in these fields. The volume provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. The book will satisfy the need for a general reference and review book for scientists studying lipids, proteins and membranes. Excellent up-to-date reviews are available on the various topics covered. A current, readable, and critical summary of these areas of research, it will allow scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances. Content: Edited by Page iii Copyright page Page iv Preface Page v Dennis Vance, Jean Vance List of contributors Pages vii-viii Chapter 1 Physical properties and functional roles of lipids in membranes Original Research Article Pages 1-33 Pieter R. Cullis, David B. Fenske, Michael J. Hope Chapter 2 Lipid metabolism in prokaryotes Original Research Article Pages 35-74 Charles O. Rock, Suzanne Jackowski, John E. Cronan Chapter 3 Oxidation of fatty acids Original Research Article Pages 75-99 Horst Schulz Chapter 4 Fatty acid synthesis in eukaryotes Original Research Article Pages 101-127 Lisa M. Salati, Alan G. Goodridge Chapter 5 Fatty acid desaturation and chain elongation in eukaryotes Original Research Article Pages 129-152 Harold W. Cook Chapter 6 Glycerolipid biosynthesis in eukaryotes Original Research Article Pages 153-181 Dennis E. Vance Chapter 7 Ether-linked lipids and their bioactive species: occurrence, chemistry, metabolism, regulation, and function Original Research Article Pages 183-210 Fred Snyder Chapter 8 Phospholipases Original Research Article Pages 211-236 Moseley Waite Chapter 9 Glycerolipids in signal transduction Original Research Article Pages 237-255 J. David Lambeth, Sung Ho Ryu Chapter 10 Adipose tissue and lipid metabolism Original Research Article Pages 257-281 David A. Bernlohr, Melanie A. Simpson Chapter 11 The eicosanoids: cyclooxygenase, lipoxygenase, and epoxygenase pathways Original Research Article Pages 283-308 William L. Smith, Frank A. Fitzpatrick Chapter 12 Sphringolipids: metabolism and cell signalling Original Research Article Pages 309-339 Alfred H. Merill Jr., Charles C. Sweeley Chapter 13 Isoprenoids, sterols and bile acids Original Research Article Pages 341-362 Peter A. Edwards, Roger Davis Chapter 14 Lipid metabolism in plants Original Research Article Pages 363-389 Katherine M. Schmid, John B. Ohlrogge Chapter 15 Lipid assembly into cell membranes Original Research Article Pages 391-423 Dennis R. Voelker Chapter 16 Assembly of proteins into membranes Original Research Article Pages 425-471 Reinhart A.F. Reithmeier Chapter 17 Structure, assembly and secretion of lipoproteins Original Research Article Pages 473-493 Roger A. Davis, Jean E. Vance Chapter 18 Dynamics of lipoprotein transport in the human circulatory system Original Research Article Pages 495-516 Phoebe E. Fielding, Christopher J. Fielding Chapter 19 Removal of lipoproteins from plasma Original Research Article Pages 517-541 Wolfgang J. Schneider Subject Index Pages 543-553 v. 1. Membrane structure / editors, J.B. Finean and R.H. Michell v. 2. Membrane transport / editors, S.L. Bonting and J.J.H.H.M. de Pont v. 3. Stereochemistry / editor, Ch. Tamm v. 4. Phospholipids / editors, J.N. Hawthorne and G.B. Ansell v. 5. Prostaglandins and related substances / editors, C. Pace-Asciak and E. Granström v. 6. The chemistry of enzyme action / editor, Michael I. Page v. 7. Fatty acid metabolism and its regulation / editor, Shosaku Numa v. 8. Separation methods / editor, Z. Deyl v. 9. Bioenergetics / editor, L. Ernster v. 10. Glycolipids / editor, H. Wiegandt v. 11. Modern physical methods in biochemistry (2 v.) v. 12. Sterols and bile acids / editors, Henry Danielsson and Jan Sjövall v. 13. Blood coagulation / editors, R.F.A. Zwaal and H.C. Hemker v. 14. Plasma lipoproteins / editor, A.M. Gotto v. 15. Photosynthesis / editor, J. Amesz v. 16. Hydrolytic enzymes / editors, A. Neuberger and K. Brocklehurst mechanisms in bioenergetics / editor, Lars Ernster v. 17. Molecular genetics of immunoglobulin / editors, F. Calabi and M.S. Neuberger v. 18. Hormones and their actions / editors, B.A. Cooke, R.J.B. King, H.J. van der Molen v. 19. Biosynthesis of tetrapyrroles / editor, P.M. Jordan v. 20. Biochemistry of lipids, lipoproteins, and memebranes / editors, Dennis E. Vance and Jean E. Vance v. 21. Molecular aspects of transport proteins / editor, J.J.H.H.M. De Pont v. 22. Membrane biogenesis and protein targetting / editors, Walter Neupert and Roland Lill v. 23. Molecular mechanisms in bioenergetics / editor, Lars Ernster v. 24. Neurotransmitter receptors / editor, Ferdinand Hucho v. 25 Protein-lipid interactions / editor, A. Watts v. 26. The biochemistry of archaea (archaebacteria) / editors, M. Kates, D.J. Kushner, A.T. Matheson v. 27. Bacterial cell wall / editors, J.-M. Ghuysen, R. Hackenbeck v. 28. Free radical damage and its control / editors, Catherine A. Rice-Evans, Roy H. Burdon v. 29a. Glycoproteins / editors, J. Montreuil, J.F.G. Vliegenthart, H. Schachter. Physical Properties And Functional Roles Of Lipids In Membranes / Pieter R. Cullis, David B. Fenske, Michael J. Hope -- Lipid Metabolism In Prokaryotes / Charles O. Rock, Suzanne Jackowski, John E. Cronan -- Oxidation Of Fatty Acids / Horst Schulz -- Fatty Acid Synthesis In Eukaryotes / Lisa M. Salati, Alan G. Goodridge -- Fatty Acid Desaturation And Chain Elongation In Eukaryotes / Harold W. Cook -- Glycerolipid Biosynthesis In Eukaryotes / Dennis E. Vance -- Ether-linked Lipids And Their Bioactive Species : Occurrence, Chemistry, Metabolism, Regulation, And Function / Fred Snyder -- Phospholipases / Moseley Waite -- Glycerolipids In Signal Transduction / J. David Lambeth, Sung Ho Ryu -- Adipose Tissue And Lipid Metabolism / David A. Bernlohr, Melanie A. Simpson -- The Eicosanoids : Cyclooxygenase, Lipoxygenase, And Epoxygenase Pathways / William L. Smith, Frank A. Fitzpatrick -- Sphringolipids : Metabolism And Cell Signalling / Alfred H. Merill Jr., Charles C. Sweeley -- Isoprenoids, Sterols And Bile Acids / Peter A. Edwards, Roger Davis -- Lipid Metabolism In Plants / Katherine M. Schmid, John B. Ohlrogge -- Lipid Assembly Into Cell Membranes / Dennis R. Voelker -- Assembly Of Proteins Into Membranes / Reinhart A.f. Reithmeier -- Structure, Assembly And Secretion Of Lipoproteins / Roger A. Davis, Jean E. Vance -- Dynamics Of Lipoprotein Transport In The Human Circulatory System / Phoebe E. Fielding, Christopher J. Fielding -- Removal Of Lipoproteins From Plasma / Wolfgang J. Schneider. Editors, Dennis E. Vance And Jean E. Vance. Includes Bibliographical References And Index. Chemical And Biochemical Aspects -- Chemistry Of Iron And Copper In Radical Reactions / W.h. Koppenol -- Some Chemical And Biochemical Constraints Of Oxidative Stress In Living Cells / Jean Chaudiere -- Ferryl Iron And Protein Free Radicals / C.e. Cooper -- Antioxidants And Free Radical Scavengers / A.t. Diplock -- Formation Of Free Radicals And Mechanisms Of Action In Normal Biochemical Processes And Pathological States / C.a. Rice-evans -- Free Radicals And Cell Proliferation / R.h. Burdon -- Pathological Aspects -- Therapeutic Iron-chelating Agents / S. Singh And R.c. Hider -- Free Radicals In Central Nervous System Injury / E.d. Hall -- Ultraviolet Radiation (uva, Uvb) And Skin Antioxidants / L. Packer -- Free Radicals And Atherosclerosis / J.c. Fruchart And P. Duriez -- Chemical Aspects Of Free Radical Reactions In Connective Tissue / B.j. Parsons -- Free Radicals And Connective Tissue Damage / M.s. Baker -- Free Radicals In Toxicology With An Emphasis On Electron Spin Resonance Investigations / R.p. Mason And C.f. Chignell. (cont) Radical Generation And Detection In Myocardial Injury / B. Kalyanaraman ... [et Al.] -- Free Radical Pathways In The Inflammatory Response / P.g. Winyard ... [et Al.]. Editors, Catherine A. Rice-evans, Roy H. Burdon. Includes Bibliographical References And Index. This is the third edition of this advanced textbook, written with two major objectives in mind. One is to provide an advanced textbook covering the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, and molecular biology. The second objective is to provide a clear summary of these research areas for scientists presently working in these fields.

The volume provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. The book will satisfy the need for a general reference and review book for scientists studying lipids, proteins and membranes. Excellent up-to-date reviews are available on the various topics covered. A current, readable, and critical summary of these areas of research, it will allow scientists to become familiar with recent developments related to their own research interests, and will help clinical researchers and medical students keep abreast of developments in basic science that are important for subsequent clinical advances. This volume provides a broad, state-of-the-art coverage of diverse technical topics in gene expression in mammalian cells, including the development of vectors for production of proteins in cultured cells, in transgenic animals, vaccination, and gene therapy; progress in methods for the transfer of genes into mammalian cells and the optimization and monitoring of gene expression; advances in our understanding and manipulation of cellular biochemical pathways that have a quantitative and qualitative impact on mammalian gene expression; and the large-scale production and purification of proteins from cultured cells. Covering the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, and molecular biology, this work provides summary of these research areas for scientists presently working in these fields. It also provides the basis for an advanced course for students in the biochemistry of lipids, lipoproteins and membranes. This textbook covers the major areas in the fields of lipid, lipoprotein, and membrane biochemistry, as well as molecular biology. It also provides a summary of these research areas for scientists presently working in these areas. This book provides up-to-date coverage at an advanced level of a range of topics in the biochemistry and molecular biology of plant hormones, with particular emphasis on biosynthesis, metabolism and mechanisms of action