بیوشیمی، زیست‌شناسی مولکولی و پیامدهای درمانی، جلد ۳۴: نیتریک اکسید: بیوشیمی، زیست‌شناسی مولکولی و پیامدهای درمانی (پیشرفت‌ها در داروشناسی، جلد ۳۴)

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. This volume contains chapters that address diverse but interrelated areas pertaining to the chemistry, biochemistry, molecular biology, and pharmacology of nitric oxide in mammalian cells. The contents form a comprehensive treatise of factors influencing the control of nitric oxide production in various cell types. Highlights * Presents comprehensive coverage of the chemical properties of nitric oxide and how they form the basis for the multifaceted biological actions for nitric oxide * Contains the most current and detailed documentation of the properties and regulation of nitric oxide synthases * Provides the most up-to-date review of inhalational nitric oxide therapy for treatment of respiratory dysfunction Content: Serial Editors Page ii Edited by Page iii Copyright page Page iv Contributors Pages xix-xxiv Chemistry of Nitric Oxide: Biologically Relevant Aspects Original Research Article Pages 1-15 Jon M. Fukuto Reactions between Nitric Oxide, Superoxide, and Peroxynitrite: Footprints of Peroxynitrite in Vivo Original Research Article Pages 17-43 John P. Crow, Joseph S. Beckman Oxygen Radical-Nitric Oxide Reactions in Vascular Diseases Original Research Article Pages 45-69 Bruce A. Freeman, C. Roger White, Hector Gutierrez, Andrés Paler-Martínez, Margaret M. Tarpey, Homero Rubbo Nitric Oxide Synthases: Gene Structure and Regulation Original Research Article Pages 71-90 Yang Wang, Philip A. Marsden Transcription of the Human Neuronal Nitric Oxide Synthase Gene in the Central Nervous System is Mediated by Multiple Promoters Original Research Article Pages 91-112 Anthony P. Young, Ferid Murad, Harald Vaessin, Jinling Xie, Terrie K. Rife Regulation of the Expression of the Inducible Isoform of Nitric Oxide Synthase Original Research Article Pages 113-153 Csaba Szabó, Christoph Thiemermann Regulation and Function of Inducible Nitric Oxide Synthase during Sepsis and Acute Inflammation Original Research Article Pages 155-170 James M. Wong, Timothy R. Billiar Expression and Expressional Control of Nitric Oxide Synthases in Various Cell Types Original Research Article Pages 171-186 Ulrich Förstermann, Hartmut Kleinert, Ingolf Gath, Petra Schwarz, Ellen I. Closs, Nae J. Dun Control and Consequences of Endothelial Nitric Oxide Formation Original Research Article Pages 187-206 Ingrid Fleming, Rudi Busse Control of Electron Transfer in Neuronal Nitric Oxide Synthase by Calmodulin, Substrate, Substrate Analogs, and Nitric Oxide Original Research Article Pages 207-213 Dennis J. Stuehr, Husam M. Abu-Soud, Denis L. Rousseau, Paul L. Feldman, Jianling Wang Negative Modulation of Nitric Oxide Synthase by Nitric Oxide and Nitroso Compounds Original Research Article Pages 215-234 Jeanette M. Griscavage, Adrian J. Hobbs, Louis J. Ignarro Regulation of Nitric Oxide Synthase: Role of Oxygen Radicals and Cations in Nitric Oxide Formation Original Research Article Pages 235-250 Chandra K. Mittal, Chander S. Mehta Why Tetrahydrobiopterin? Original Research Article Pages 251-261 Bernd Mayer, Ernst R. Werner Nitric Oxide and cGMP Signaling Original Research Article Pages 263-275 Lee J. McDonald, Ferid Murad Nitric Oxide and Intracellular Heme Original Research Article Pages 277-291 Young-Myeong Kim, Hector A. Bergonia, Claudia Müller, Bruce R. Pitt, W. David Watkins, Jack R. Lancaster Jr. High-Level Expression of Biologically Active Soluble Guanylate Cyclase Using the Baculovirus System is Strongly Heme-Dependent Original Research Article Pages 293-303 Wolfgang A. Buechler, Sujay Singh, Janet Aktas, Stefan Müller, Ferid Murad, Rupert Gerzer cGMP Signaling through cAMP- and cGMP-Dependent Protein Kinases Original Research Article Pages 305-322 Thomas M. Lincoln, Padmini Komalavilas, Nancy J. Boerth, Lee Ann MacMillan-Crow, Trudy L. Cornwell Physiological and Toxicological Actions of Nitric Oxide in the Central Nervous System Original Research Article Pages 323-342 Valina L. Dawson, Ted M. Dawson S-Nitrosothiols: Chemistry, Biochemistry, and Biological Actions Original Research Article Pages 343-349 Gilbert R. Upchurch Jr., George N. Welch, Joseph Loscalzo Glyceraldehyde-3-phosphate Dehydrogenase: A Target for Nitric Oxide Signaling Original Research Article Pages 351-360 Bernhard Brüne, Eduardo G. Lapetina Nitric Oxide Donors: Biochemical Pharmacology and Therapeutics Original Research Article Pages 361-381 John Anthony Bauer, Brian P. Booth, Ho-Leung Fung Nitric Oxide Donors: A Continuing Opportunity in Drug Design Original Research Article Pages 383-398 Stephen R. Hanson, Thomas C. Hutsell, Larry K. Keefer, Daniel L. Mooradian, Daniel J. Smith Nitric Oxide and Peripheral Adrenergic Neuromodulation Original Research Article Pages 399-413 Roberto Levi, Kwan Ha Park, Michiaki Imamura, Nahid Seyedi, Harry M. Lander A Study on Tumor Necrosis Factor, Tumor Necrosis Factor Receptors, and Nitric Oxide in Human Fetal Glial Cultures Original Research Article Pages 415-438 Barbara A. St. Pierre, Douglas A. Granger, Joyce L. Wong, Jean E. Merrill Inhaled Nitric Oxide, Clinical Rationale and Applications Original Research Article Pages 439-456 Claes G. Frostell, Warren M. Zapol Inhaled Nitric Oxide Therapy of Pulmonary Hypertension and Respiratory Failure in Premature and Term Neonates Original Research Article Pages 457-474 Steven H. Abman, John P. Kinsella Clinical Applications of Inhaled Nitric Oxide in Children with Pulmonary Hypertension Original Research Article Pages 475-504 David L. Wessel, Ian Adatia Index Pages 505-516 Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. This volume contains chapters that address diverse but interrelated areas pertaining to the chemistry, biochemistry, molecular biology, and pharmacology of nitric oxide in mammalian cells. The contents form a comprehensive treatise of factors influencing the control of nitric oxide production in various cell types.

Highlights
* Presents comprehensive coverage of the chemical properties of nitric oxide and how they form the basis for the multifaceted biological actions for nitric oxide
* Contains the most current and detailed documentation of the properties and regulation of nitric oxide synthases
* Provides the most up-to-date review of inhalational nitric oxide therapy for treatment of respiratory dysfunction Part of a series providing reviews on pharmacological topics, this volume contains chapters addressing diverse but closely interrelated areas in chemistry, biochemistry, molecular biology, and pharmacology of nitric oxide in mammalian cells.