Biochemical Actions of Hormones. Volume 11

Biochemical Actions of Hormones, Volume XI is a 12-chapter text that covers the general and specific biochemical aspects of polypeptide and steroid hormones. The introductory chapters deal with the biochemical actions of the leukotrienes, the cyclic adenosine monophosphate, and the gonadotropin releasing hormone. The next chapters highlight detailed contributions on polypeptide hormone research. These chapters specifically tackle the insulin actions and the role of insulin in mammary gland development. The last series of chapters on steroid hormones includes X-ray crystallographic analysis of steroid structures and the significance of these studies on steroid-receptor interactions. These chapters also explore the analysis of the estrogen receptor with monoclonal antibodies; the role of estrogen receptor in responsive mammalian cells; the use of peroxidase as a marker of catechol estrogen action; and the activation and stabilization of the glucocorticoid receptor. This volume will be of great benefit to biochemists, biologists, endocrinologists, and researchers who are interested in the hormonal action and regulation. Content: Contributors , Page ii Front Matter , Page iii Copyright , Page iv Contributors , Pages ix-xi Preface , Page xiii , Gerald Litwack CHAPTER 1 - The Leukotrienes , Pages 1-23 , Sven Hammarström CHAPTER 2 - Molecular Approaches to the Study of Cyclic AMP Action , Pages 25-65 , Robert A. Steinberg CHAPTER 3 - Molecular Mechanism of Gonadotropin Releasing Hormone Action , Pages 67-92 , P. Michael Conn CHAPTER 4 - Mechanisms of Biological Signaling by the Insulin Receptor , Pages 93-125 , Michael P. Czech, Joan Massagué, Jonathan R. Seals, Kin-Tak Yu CHAPTER 5 - Antibodies to the Insulin Receptor: Studies of Receptor Structure and Function , Pages 127-162 , C. Ronald Kahn, José A. Hedo, Masato Kasuga CHAPTER 6 - Insulin Biology from the Perspective of Studies on Mammary Gland Development , Pages 163-186 , Yale J. Topper, Kevin R. Nicholas, Lakshmanan Sankaran, Jerzy K. Kulski CHAPTER 7 - Steroid Hormone Action Interpreted from X-Ray Crystallographic Studies , Pages 187-206 , William L. Duax, Jane F. Griffin, Douglas C. Rohrer, Charles M. Weeks, Richard H. Ebright CHAPTER 8 - Application of Immunochemical Techniques to the Analysis of Estrogen Receptor Structure and Function , Pages 207-239 , Geoffrey L. Greene CHAPTER 9 - Role of the Estrogen Receptor in Estrogen-Responsive Mammalian Cells , Pages 241-266 , Henri Rochefort, Bruce Westley CHAPTER 10 - Catechol Estrogens , Pages 267-307 , Eytan R. Barnea, Neil J. MacLusky, Frederick Naftolin CHAPTER 11 - Peroxidase: A Marker for Estrogen Expression , Pages 309-345 , Eugene R. DeSombre CHAPTER 12 - Inactivation, Activation, and Stabilization of Glucocorticoid Receptors , Pages 347-376 , Paul R. Housley, Joseph F. Grippo, Mary K. Dahmer, William B. Pratt Index , Pages 377-382 Contents of Previous Volumes , Pages 383-392