Bioactive natural products : opportunities and challenges in medicinal chemistry

Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developing pharmaceuticals to treat various ailments and disease manifestations. 1. Natural products in drug discovery: impacts and opportunities - an assessment / Goutam Brahmachari -- 2. Vascular regulation by small peptides / Toshiro Matsui, Zhengquan Wang and Mitsuru Tanaka -- 3. Key natural products in malaria chemotherapy: from quinine to artemisinin and beyond / Jean Fotie -- 4. Natural product inhibitors and activators of Histone Deacetylases / Michael D. Scott, Manas K. Haldar and Sanku Mallik -- 5. Artemisinin: a promise for the development of potent anticancer agents / Daniel L. da Silva [und weitere] -- 6. Andrographolide: a plant-derived natural molecule of pharmaceutical promise / Goutam Brahmachari -- 7. Natural products in Alzheimer's disease: impacts and prospects / Shri Kant Mishra, Mark C. Stahl and Parampreet Singh -- 8. Use of multi-nutrient functional peptide complex for treatment and prevention of viral infections / Viktor Lozitsky [und weitere] -- 9. Anti-infective flavonoids: an overview / Maria Jose Abad [und weitere] -- 10. Anti-Helicobacter Pylori activities of compounds of natural origin / Temitope O. Lawal [und weitere] -- 11. Natural bioactive principles in the treatment of skin diseases / Emmanuel C. Ibezim -- 12. Anti-diabetic agents of natural origin: a retrospective account of some promising chemotypes / Goutam Brahmachari -- 13. Fermentation improvement of processes yielding natural products for industry / Arnold L. Demain and Sergio Sanchez -- 14. Plant cell culture and transgenic plants: the goldmines for the production of compounds of pharmacological interest / Ana Paula de Faria [und weitere] Bioactive natural products are a rich source of novel therapeutics. This volume, which comprises sixteen chapters on natural products chemistry, brings together an overview of the discoveries in this field. It also provides information on the industrial application of natural products for medicinal purposes.