Behavioral Neurobiology of Stress-related Disorders (Current Topics in Behavioral Neurosciences Book 18)

"Stress is such an over-used word that it is at time difficult to define its core features When is an environment stressful? What does a stressful environment do to the brain and to the body? What are the biological mechanisms by which a stressor affects us? How does stress contributes to the onset and the progression of mental disorders? How do the effects of stress change over the life-time of an individual? These are just some of the overarching questions addressed by this book, thanks to the contribution of some of the world leading experts on the neurobiology of stress at the pre-clinical and clinical levels Topics include current advances on the neurobiology of stress on various neurobiological systems such as immune, hypothalamic-pituitary-adrenal (HPA) axis, neurogenesis and neuroplasticity, neurotransmitter (glutamate, noradrenaline, dopamine, serotonin and endocannabinoid), neuropeptides, cognition and emotional processing as well as in utero and early postnatal effects The clinical chapters deal with the relationship of stress and mental disorders such as depression, posttraumatic stress disorder (PTSD), anxiety disorders, schizophrenia, bipolar disorder, substance abuse and addiction, dementia and age-related cognitive decline as well as resilience to stress Thus, this book brings together some of the most updated and authoritative views on the effects of stress of brain and behavior - Font no determinada Front Matter....Pages i-x Neuronal-Glial Mechanisms of Exercise-Evoked Stress Robustness....Pages 1-12 The Interface of Stress and the HPA Axis in Behavioural Phenotypes of Mental Illness....Pages 13-24 Adult Hippocampal Neurogenesis in Depression: Behavioral Implications and Regulation by the Stress System....Pages 25-43 Impact of Stress on Prefrontal Glutamatergic, Monoaminergic and Cannabinoid Systems....Pages 45-66 Interaction of Stress, Corticotropin-Releasing Factor, Arginine Vasopressin and Behaviour....Pages 67-80 Long-lasting Consequences of Early Life Stress on Brain Structure, Emotion and Cognition....Pages 81-92 Mechanisms Linking In Utero Stress to Altered Offspring Behaviour....Pages 93-122 Does Stress Elicit Depression? Evidence From Clinical and Preclinical Studies....Pages 123-159 Neurobehavioral Mechanisms of Traumatic Stress in Post-traumatic Stress Disorder....Pages 161-190 Investigation of Cortisol Levels in Patients with Anxiety Disorders: A Structured Review....Pages 191-216 Stress, Schizophrenia and Bipolar Disorder....Pages 217-235 Stress, Substance Abuse, and Addiction....Pages 237-263 Role of Stress, Depression, and Aging in Cognitive Decline and Alzheimer’s Disease....Pages 265-296 Stress and Psychological Resiliency....Pages 297-312 Back Matter....Pages 313-315