Basics of Bioinformatics : Lecture Notes of the Graduate Summer School on Bioinformatics of China

This book outlines 11 courses and 15 research topics in bioinformatics, based on curriculums and talks in a graduate summer school on bioinformatics that was held in Tsinghua University. The courses include: Basics for Bioinformatics, Basic Statistics for Bioinformatics, Topics in Computational Genomics, Statistical Methods in Bioinformatics, Algorithms in Computational Biology, Multivariate Statistical Methods in Bioinformatics Research, Association Analysis for Human Diseases: Methods and Examples, Data Mining and Knowledge Discovery Methods with Case Examples, Applied Bioinformatics Tools, Foundations for the Study of Structure and Function of Proteins, Computational Systems Biology Approaches for Deciphering Traditional Chinese Medicine, and Advanced Topics in Bioinformatics and Computational Biology. This book can serve as not only a primer for beginners in bioinformatics, but also a highly summarized yet systematic reference book for researchers in this field. Rui Jiang and Xuegong Zhang are both professors at the Department of Automation, Tsinghua University, China. Professor Michael Q. Zhang works at the Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA. Front Matter....Pages i-xix Basics for Bioinformatics....Pages 1-25 Basic Statistics for Bioinformatics....Pages 27-68 Topics in Computational Genomics....Pages 69-100 Statistical Methods in Bioinformatics....Pages 101-149 Algorithms in Computational Biology....Pages 151-161 Multivariate Statistical Methods in Bioinformatics Research....Pages 163-231 Association Analysis for Human Diseases: Methods and Examples....Pages 233-242 Data Mining and Knowledge Discovery Methods with Case Examples....Pages 243-270 Applied Bioinformatics Tools....Pages 271-301 Foundations for the Study of Structure and Function of Proteins....Pages 303-336 Computational Systems Biology Approaches for Deciphering Traditional Chinese Medicine....Pages 337-368 Advanced Topics in Bioinformatics and Computational Biology....Pages 369-395 Erratum....Pages E1-E2