Basic and Clinical Aspects of Malignant Melanoma (Cancer Treatment and Research, 35)

Where do you begin to look for a recent, authoritative article on the diagnosis or management of particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfortunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes which aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion. First, by dividing the oncology literature into specific subdividions such as lung cancer, genitouri­ nary cancer, pediatric oncology, etc. Second, by asking eminent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more. Front Matter....Pages i-xiv Front Matter....Pages 1-1 The Role of Oncogenes in the Pathogenesis of Malignant Melanoma....Pages 3-39 Laminin and Fibronectin Modulate the Metastatic Activity of Melanoma Cells....Pages 41-60 Structure, Function, and Biosynthesis of Ganglioside Antigens Associated with Human Tumors Derived From the Neuroectoderm....Pages 61-86 Front Matter....Pages 87-87 Epidemiology of Ocular Melanoma....Pages 89-117 Malignant Melanoma: Prognostic Factors....Pages 119-130 Endocrine Influences on the Natural History of Human Malignant Melanoma....Pages 131-139 Psychosocial Factors Associated with Prognostic Indicators, Progression, Psychophysiology, and Tumor-host Response in Cutaneous Malignant Melanoma....Pages 141-154 Central nervous system metastases in malignant melanoma....Pages 155-163 Front Matter....Pages 165-165 Interferon Trials in the Management of Malignant Melanoma and Other Neoplasms: An Overview....Pages 167-194 The treatment of Malignant Melanoma by Fast Neutrons....Pages 195-213 Back Matter....Pages 215-222