Bacterial Pathogenesis : A Molecular Approach, Third Edition

Written as a text for one-semester microbiology courses, the third edition of the highly acclaimed Bacterial Pathogenesis draws together the latest research to help students explore the mechanisms by which bacterial pathogens cause infections in humans and animals. It features two additional authors who offer new points of view to ensure that all facets of the field are thoroughly explored. Readers will discover the strategies that bacterial pathogens use to survive and multiply within their hosts as well as the strategies that hosts use to fend off infections. At the same time, the text s engaging style, illustrative examples, and thought-provoking exercises convey the excitement and fun of scientific discovery.Completely revised and updated, this third edition features a new organization that dispenses with separate chapters dedicated to individual bacterial pathogens. Instead it focuses on core principles based on the growing understanding of the underlying similarities among pathogens and their mechanisms of action. In addition, readers familiar with the previous edition will find much new material. For example, there is new coverage of key findings on the mechanisms of bacterial secretion, toxins, and regulation.Study questions at the end of each chapter challenge students to probe more deeply into the issues covered. This edition also offers new problems that immerse students in the discovery process. These problems present actual research data, asking students to interpret the data and then devise new experiments that would help build their understanding. New to the Third EditionPresents new paradigms that unify concepts in the field of bacterial pathogenesisChallenges students to interpret actual research data and design new experimentsExplores the latest findings on the mechanisms of bacterial secretion, toxins, and regulationExpands coverage of the role of normal microbial populations of the human body in health and diseaseIncludes two new authors offering additional perspectives and points of view Paperback, 540 pages, two-color illustrations throughout, glossary, index. Written as a text for one-semester microbiology courses, the third edition of the highly acclaimed Bacterial Pathogenesis draws together the latest research to help students explore the mechanisms by which bacterial pathogens cause infections in humans and animals. It features two additional authors who offer new points of view to ensure that all facets of the field are thoroughly explored. Readers will discover the strategies that bacterial pathogens use to survive and multiply within their hosts as well as the strategies that hosts use to fend off infections. At the same time, the text’s engaging style, illustrative examples, and thought-provoking exercises convey the excitement and fun of scientific discovery. Completely revised and updated, this third edition features a new organization that dispenses with separate chapters dedicated to individual bacterial pathogens. Instead it focuses on core principles based on the growing understanding of the underlying similarities among pathogens and their mechanisms of action. In addition, readers familiar with the previous edition will find much new material. For example, there is new coverage of key findings on the mechanisms of bacterial secretion, toxins, and regulation. Study questions at the end of each chapter challenge students to probe more deeply into the issues covered. This edition also offers new problems that immerse students in the discovery process. These problems present actual research data, asking students to interpret the data and then devise new experiments that would help build their understanding. New to the Third Edition Key Features For more on the book and information on requesting an examination copy please visit http://www.asmscience.org/instructors. Click here to see ASM's "Author Insights" interview with Bacterial Pathogenesis' author Brenda Wilson, PhD. Paperback, 540 pages, two-color illustrations throughout, glossary, index. Interested in purchasing this title as an electronic publication? Click here for the electronic version on Vital Source! Click here for the electronic version on CourseSmart! The power of bacteria Skin and mucosa : the first lines of defense against bacterial infections The innate immune system : always on guard The second line of defense : antibodies and cytotoxic T cells The normal human microbiota Microbes and disease : establishing a connection Mechanisms of genetic modification and exchange : role in pathogen evolution Identification of virulence factors : measuring infectivity and virulence Identification of virulence factors : molecular approaches for bacterial factors Identification of virulence factors : molecular approaches for host factors Bacterial strategies for evading or surviving host defense systems Toxins and other toxic virulence factors Delivery of virulence factors Virulence regulation Antibiotics and their targets How bacteria become resistant to antibiotics Vaccination : an underappreciated component of the modern medical armamentarium Gram-positive opportunistic pathogens Gram-negative opportunistic pathogens and emerging pathogens Biosecurity : the changing roles of microbiologists in an age of bioterrorism and Emerging diseases.

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"Written for one-semester microbiology courses, the third edition draws together the latest research to help students explore the mechanisms by which bacterial pathogens cause infections in humans and animals. Readers discover the strategies that bacterial pathogens use to survive and multiply within their hosts and the strategies that hosts use to fend off infections. The text's engaging style, illustrative examples, and thought-provoking exercises convey the excitement of scientific discovery"--Publisher's description Completely revised and updated to capture new research findings, the third edition of this best-selling text is designed to provide a comprehensive introduction to bacterial pathogenesis for both students and researchers. The authors integrate material from pathogenic microbiology, molecular biology, immunology, and human physiology to provide a complete but accessible overview of the field Discover the strategies bacterial pathogens use to survive and multiply. This textbook focuses on core principles based on the growing understanding of the underlying similarities among pathogens and their mechanisms of action, and is a recommended text for one-semester microbiology courses.