Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging : Volume 10

__Autophagy: Cancer, Other Pathologies, Inflammation, Immunity, Infection, and Aging, Volume 10__ offer a valuable guide to both cellular processes, while encouraging researchers to explore their potentially important connections. Autophagy serves to maintain healthy cells, tissues, and organs, but also promotes cancer survival and growth of established tumors. Impaired or deregulated autophagy can also contribute to disease pathogenesis. This is the tenth volume of the multivolume series that discusses, in detail, almost all aspects of the autophagy machinery in the context of health, cancer, and other pathologies. Autophagy maintains homeostasis during starvation or stress conditions by balancing the synthesis of cellular components and their deregulation by autophagy. Volume 10 of the Autophagy series discusses the role of a novel binuclear palladacycle complex that inhibits melanoma growth through apoptosis and autophagy. * Presents the most advanced information regarding the role of the autophagic system in life and death * Contains a direct focus on the role of a novel binuclear palladacycle complex that inhibits melanoma growth * Introduces new, more effective therapeutic strategies in the development of targeted drugs and programmed cell death, providing information that will aid in preventing detrimental inflammation * States recent advancements in the molecular mechanisms underlying a large number of genetic and epigenetic diseases and abnormalities * Edited work with chapters authored by leaders in the field from around the globe―the broadest, most expert coverage available Content: Front-matter,Copyright,Dedication,10 Lines of Autophagy for Volume 10,Dedication,Mitophagy and Biogenesis,Autophagy and Cancer,Some Thoughts on Autophagy and Immunity,Autophagy: Friend or Foe?,Autophagy: If and When,What Happened When Autophagy Didn’t,Sugar Isn’t Always Sweet,Mitochondrial Mysteries,A Photo Is Static, An Instant in Time,Autophagy Subversion,Foreword,Foreword,Preface,Contributors,Autophagy: Volume 1—Contributions,Autophagy: Volume 2—Contributions,Autophagy: Volume 3—Contributions,Autophagy: Volume 4—Contributions,Autophagy: Volume 5—Contributions,Autophagy: Volume 6—Contributions,Autophagy: Volume 7—Contributions,Autophagy: Volume 8—Contributions,Autophagy: Volume 9—ContributionsEntitled to full textPart I: Molecular MechanismsChapter 1 - Overview of Autophagy, Pages 3-84, M.A. Hayat Chapter 2 - Molecular Mechanisms Underlying the Degradation of Peroxisomes, Pages 85-98, Kai Mao Chapter 3 - Role of Poly(ADP-Ribose) in Catalyzing Starvation-Induced Autophagy, Pages 99-118, José Manuel Rodríguez-Vargas, F. Javier Oliver Chapter 4 - Cross-Talk Between Autophagy and Death Receptor Signaling Pathways, Pages 119-133, Kelly Airiau, Mojgan Djavaheri-Mergny Chapter 5 - Role of Autophagy in Mammalian Embryogenesis: Response to Developmental Programs, Pages 135-145, Yoh Wada, Ge-Hong Sun-Wada Chapter 6 - Autophagy in Adipose Tissue, Pages 147-156, Yuhei Mizunoe, Yuka Sudo, Naoyuki Okita, Yoshikazu Higami Chapter 7 - Prevention of Adverse Metabolic Consequences of Adipocyte Dysfunction Using MR Antagonists, Pages 157-167, Massimiliano Caprio, Vincenzo Marzolla, Andrea Armani Chapter 8 - A Rapid Method for Detecting Autophagy Activity in Live Cells Using Cellometer Image Cytometry, Pages 169-183, Leo Li-Ying Chan, Ning Lai, Dee Shen, Alisha R. Wilkinson, Wayne Patton, Eric Chan, Dmitry Kuksin, Bo Lin, Jean Qiu Chapter 9 - Cdc37: Implications in Regulation of Kinases and Proteins Linked to Neurodegenerative and Other Diseases, Pages 187-196, Malathi Narayan, Umesh K. Jinwal Chapter 10 - Autophagy in the Degeneration of Optic Nerve and Spinal Cord Axons, Pages 197-211, Jan Christoph Koch, Vinicius Toledo Ribas, Paul Lingor Chapter 11 - Membrane Type-1 Matrix Metalloproteinase-Regulated Autophagy: A Role in Brain Cancer Chemoresistance, Pages 213-230, Jonathan Pratt, Michael J. Coady, Borhane Annabi Chapter 12 - Induction of Autophagy and Apoptosis in Melanoma Treated With Palladacycle Complexes, Pages 231-247, Saeb Aliwaini, Jenna Bleloch, Serah Kimani, Sharon Prince Chapter 13 - Autophagy in Atherosclerosis, Pages 249-264, Mandy O.J. Grootaert, Ammar Kurdi, Dorien G. De Munck, Wim Martinet, Guido R.Y. De Meyer Abbreviations and Glossary, Pages 265-279 Index, Pages 281-294