Atlas of Touch Preparation Cytopathology by springer ,Liron Pantanowitz, MD / Juan Xing, MD / Sara E. Monaco, MD

“This is a “must need” for any cytology laboratory performing touch preparations as part of their service or those wanting to offer this to their physicians as an alternative approach to the standard FNA or frozen section... and [it] would be a great addition to your reference library.” ---The ASC Bulletin This is the first atlas dedicated to touch preparation cytopathology. Written by established pathologists who are at the cutting edge of this minimally-invasive practice, the Atlas of Touch Preparation Cytopathology presents a comprehensive overview and visual reference guide to the diagnostic applications of touch preparations. This visually-stunning book reviews touch preparations corresponding to all major body systems and includes chapters on specimen handling and processing, intraoperative use during frozen sections, as well as on ancillary testing using touch preps. While most cytopathology atlases have images of smears and fluids, they have very little discussion of touch preparations making this volume a one-of-a-kind resource. The authors, using many picturesque examples in the text, not only include detailed visual and textual discussion of touch preparations but also provide comparative presentations to facilitate correlation with histopathology, FNA smears and ancillary test results. This total coverage illuminates key findings and important considerations of this technique that pathologists can learn from. Written with the practicing pathologist in mind, the Atlas of Touch Preparation Cytopathology is an invaluable book in today‚Äôs pathology practice where there is increasing utilization of small biopsies that can benefit from intraprocedural evaluation and assessment to maximize diagnostic yield. Key Features: Covers various methods of touch preparation and addresses measures to avoid pitfalls. Includes techniques that can serve as helpful tricks during intraprocedural evaluation of small biopsies and at the time of frozen section. Comprehensive coverage of different body systems that are typically sampled with small biopsies and amenable to touch preparations. Contains over 400 touch preparation images and includes corresponding histopathologic figures and ancillary studies. Cover Title Copyright Contents Contributors Preface Share Atlas of Touch Preparation Cytopathology Chapter 1: Introduction Background Accuracy and Performance Advantages and Disadvantages Billing Conclusion Acknowledgment References Chapter 2: Preparation Techniques Introduction Slide Preparation Touch Preparation Imprint Cytoscrape Crush (Squash) Preparation Fixation and Staining Problems and Pitfalls Loss of Material Artifacts References Chapter 3: Intraoperative Cytology Introduction Imprint Technique Fixation and Staining Methods Rapid H&E Stain DQ Stain Rapid Pap Stain Suitable Samples Hematolymphoid Specimens Small Round Blue Cell Tumors Bone Tissue Small Biopsy Specimens Sentinel Lymph Nodes Tumor Margins Neuropathology Samples Breast Specimens Thyroid Gland Parathyroid Glands Products of Conception Unsuitable Samples Diagnostic Errors False-Positive Diagnoses False-Negative Diagnoses References Chapter 4: Gynecological System Introduction Normal Ovary Uterus and Cervix Benign Entities Ovary Uterus Malignant Entities Ovary Uterus References Chapter 5: Respiratory System Introduction Normal Bronchial Epithelial Cells Alveolar Macrophages Inflammatory Cells and Infection Benign Entities Reactive Changes Radiation Type Changes Neoplasms Malignant Entities Adenocarcinoma Squamous Cell Carcinoma Non-Small Cell Carcinoma, Not Otherwise Specified (NOS) Small Cell Carcinoma Large Cell Neuroendocrine Carcinoma Large Cell Carcinomas Lymphoma Malignant Melanoma Metastatic Tumors Sarcoma References Chapter 6: Hematopathology Introduction Normal Lymph Node Spleen Bone Marrow Benign Entities Reactive Lymphoid Hyperplasia Granulomatous Lymphadenitis Dermatopathic Lymphadenopathy Rosai–Dorfman Disease Cat Scratch Disease Acute Suppurative Lymphadenitis Mycobacterial Infection Fungal Infection Infectious Mononucleosis HIV Lymphadenopathy Malignant Entities Lymphoblastic Lymphoma Hodgkin Lymphoma Non-Hodgkin Lymphoma Posttransplant Lymphoproliferative Disorders Plasma Cell Neoplasia Myeloid Neoplasms Histiocytic and Dendritic Cell Neoplasms Metastases References Chapter 7: Genitourinary System Introduction Normal Normal Kidney Normal Urothelium Normal Prostate Normal Testis Benign and Malignant Lesions Kidney Renal Pelvis, Ureter, Urinary Bladder, and Urethra Prostate Testis Nonneoplastic Lesions Testicular Neoplasms Tumors of the Penis References Chapter 8: Pancreatobiliary, Liver, and Gastrointestinal Tract Introduction Normal Pancreas Gastrointestinal Liver Benign Entities Pancreatobiliary Tract Gastrointestinal Tract Liver Malignant Entities Pancreatobiliary Tract Gastrointestinal Tract, Including Presentation as Metastatic Disease Primary Tumors of the Liver References Chapter 9: Head and Neck Introduction Normal Benign Entities Thyroid Gland Parathyroid Gland Salivary Gland Malignant Entities Thyroid Gland Parathyroid Gland Salivary Gland Squamous Cell Carcinoma of the Head and Neck References Chapter 10: Bone and Soft Tissue Introduction Bone Tissue Normal Bone and Cartilage Cartilage Tumors Osteogenic Tumors Fibrous, Fibrohistiocytic, and Fibroosseous Tumors Small-Round-Cell Tumors Giant Cell–Rich Tumors Miscellaneous Tumors Bone Metastases Soft Tissue Normal Soft Tissue Lipomatous Tumors Spindle Cell Lesions Small-Round-Cell Tumors Myxoid Tumors Epithelioid Tumors Giant Cell Lesions Pleomorphic Tumors References Chapter 11: Central Nervous System Introduction Sellar Region Normal Pituitary Pituitary Adenoma Other Neoplastic and Nonneoplastic Lesions of the Sellar Region Extra-Axial Lesions Meningioma Other Extra-axial Neoplasms Spinal Epidural Tumors Intra-Axial Lesions Normal Nonneoplastic Lesions Primary CNS Neoplasms Metastatic Neoplasms References Chapter 12: Mediastinum, Retroperitoneum, and Adrenal Glands Introduction Normal Benign Entities Mediastinum and Retroperitoneum Adrenal Gland Malignant Entities Mediastinum and Retroperitoneum Adrenal Glands References Chapter 13: Ancillary Testing Introduction Material for Ancillary Testing Unstained Touch Preparations Destained Touch Preparations Scrape From Touch Preparation Into a Formalin-Fixed Paraffin Embedded Cell Block or Cell Transfer of Material From a Touch Preparation Formalin-Fixed Paraffin Embedded Core Needle Biopsy Types of Ancillary Testing Special Stains Immunohistochemical Stains Fluorescence In Situ Hybridization Molecular Genetic Testing Flow Cytometry Pitfalls of Ancillary Testing References Index Copyright Title Page Dedication Contents Chapter 1: ‘I’m thinking’ – Oh, but are you? Chapter 2: Renegade perception Chapter 3: The Pushbacker sting Chapter 4: ‘Covid’: The calculated catastrophe Chapter 5: There is no ‘virus’ Chapter 6: Sequence of deceit Chapter 7: War on your mind Chapter 8: ‘Reframing’ insanity Chapter 9: We must have it? So what is it? Chapter 10: Human 2.0 Chapter 11: Who controls the Cult? Chapter 12: Escaping Wetiko Postscript Appendix: Cowan-Kaufman-Morell Statement on Virus Isolation Bibliography Index "This is a "must need" for any cytology laboratory performing touch preparations as part of their service or those wanting to offer this to their physicians as an alternative approach to the standard FNA or frozen section... and [it] would be a great addition to your reference library." —-The ASC Bulletin This is the first atlas dedicated to touch preparation cytopathology. Written by established pathologists who are at the cutting edge of this minimally-invasive practice, the Atlas of Touch Preparation Cytopathology presents a comprehensive overview and visual reference guide to the diagnostic applications of touch preparations. This visually-stunning book reviews touch preparations corresponding to all major body systems and includes chapters on specimen handling and processing, intraoperative use during frozen sections, as well as on ancillary testing using touch preps. While most cytopathology atlases have images of smears and fluids, they have very little discussion of touch preparations making this volume a one-of-a-kind resource. The authors, using many picturesque examples in the text, not only include detailed visual and textual discussion of touch preparations but also provide comparative presentations to facilitate correlation with histopathology, FNA smears and ancillary test results. This total coverage illuminates key findings and important considerations of this technique that pathologists can learn from. Written with the practicing pathologist in mind, the Atlas of Touch Preparation Cytopathology is an invaluable book in today‚Äôs pathology practice where there is increasing utilization of small biopsies that can benefit from intraprocedural evaluation and assessment to maximize diagnostic yield. Key Features: Covers various methods of touch preparation and addresses measures to avoid pitfalls. Includes techniques that can serve as helpful tricks during intraprocedural evaluation of small biopsies and at the time of frozen section. Comprehensive coverage of different body systems that are typically sampled with small biopsies and amenable to touch preparations. Contains over 400 touch preparation images and includes corresponding histopathologic figures and ancillary studies. Cover -- Title -- Copyright -- Contents -- Contributors -- Preface -- Share Atlas of Touch Preparation Cytopathology -- Chapter 1: Introduction -- Background -- Accuracy and Performance -- Advantages and Disadvantages -- Billing -- Conclusion -- Acknowledgment -- References -- Chapter 2: Preparation Techniques -- Introduction -- Slide Preparation -- Touch Preparation -- Imprint -- Cytoscrape -- Crush (Squash) Preparation -- Fixation and Staining -- Problems and Pitfalls -- Loss of Material -- Artifacts -- References -- Chapter 3: Intraoperative Cytology -- Introduction -- Imprint Technique -- Fixation and Staining Methods -- Rapid H & E Stain -- DQ Stain -- Rapid Pap Stain -- Suitable Samples -- Hematolymphoid Specimens -- Small Round Blue Cell Tumors -- Bone Tissue -- Small Biopsy Specimens -- Sentinel Lymph Nodes -- Tumor Margins -- Neuropathology Samples -- Breast Specimens -- Thyroid Gland -- Parathyroid Glands -- Products of Conception -- Unsuitable Samples -- Diagnostic Errors -- False-Positive Diagnoses -- False-Negative Diagnoses -- References -- Chapter 4: Gynecological System -- Introduction -- Normal -- Ovary -- Uterus and Cervix -- Benign Entities -- Ovary -- Uterus -- Malignant Entities -- Ovary -- Uterus -- References -- Chapter 5: Respiratory System -- Introduction -- Normal -- Bronchial Epithelial Cells -- Alveolar Macrophages -- Inflammatory Cells and Infection -- Benign Entities -- Reactive Changes -- Radiation Type Changes -- Neoplasms -- Malignant Entities -- Adenocarcinoma -- Squamous Cell Carcinoma -- Non-Small Cell Carcinoma, Not Otherwise Specified (NOS) -- Small Cell Carcinoma -- Large Cell Neuroendocrine Carcinoma -- Large Cell Carcinomas -- Lymphoma -- Malignant Melanoma -- Metastatic Tumors -- Sarcoma -- References -- Chapter 6: Hematopathology -- Introduction -- Normal -- Lymph Node -- Spleen -- Bone Marrow