Atlas of Comparative Diagnostic and Experimental Hematology: Smith/Atlas of Comparative Diagnostic and Experimental Hematology

A vital resource on blood and bone marrow cell morphology in laboratory animal medicine. This fully revised new edition is an essential reference for clinical pathologists in diagnostic laboratories, and medical or veterinary research. The atlas contains over 400 color images of cells from the peripheral blood and bone marrow from a variety of animals encountered in laboratory animal medicine, in health and disease. Key features: New chapter on flow cytometry and its application in terms of routine analyses as a means of identifying abnormalities in cell marker expression, which is of particular relevance for pre-clinical safety assessment Covers the most recent developments in laboratory animal hematology, including parameters measured by the latest generation of analyzers Coverage of a wide range of laboratory animal species, as well as those used in clinical veterinary trials Photomicrographs present normal and abnormal blood cells from a variety of hematological conditions along with descriptive text Content: Chapter 1 Rodents (pages 1–36): Clifford Smith and Alfred Jarecki Chapter 2 Rabbit (pages 37–39): Clifford Smith and Alfred Jarecki Chapter 3 Cat (pages 41–44): Clifford Smith and Alfred Jarecki Chapter 4 Dog (pages 45–64): Clifford Smith and Alfred Jarecki Chapter 5 Monkey (pages 65–87): Clifford Smith and Alfred Jarecki Chapter 6 Other Species (pages 89–103): Clifford Smith and Alfred Jarecki Chapter 7 Blood Collection Procedures (pages 105–106): Clifford Smith and Alfred Jarecki Chapter 8 Artifacts (pages 107–114): Clifford Smith and Alfred Jarecki Chapter 9 Bone Marrow (pages 115–120): Geoff Brown Chapter 10 Comparative Applications in Flow Cytometry (pages 121–133): Alaa Saad A Vital Resource On Blood And Bone Marrow Cell Morphology In Laboratory Animal Medicine. This Fully Revised New Edition Is An Essential Reference For Clinical Pathologists In Diagnostic Laboratories, And Medical Or Veterinary Research. The Atlas Contains Over 400 Color Images Of Cells From The Peripheral Blood And Bone Marrow From A Variety Of Animals Encountered In Laboratory Animal Medicine, In Health And Disease. Key Features: New Chapter On Flow Cytometry And Its Application In Terms Of Routine Analyses As A Means Of Identifying Abnormalities In Cell Marker Expression, Which Is Of Particular Relevance For Pre-clinical Safety Assessment Covers The Most Recent Developments In Laboratory Animal Hematology, Including Parameters Measured By The Latest Generation Of Analyzers Coverage Of A Wide Range Of Laboratory Animal Species, As Well As Those Used In Clinical Veterinary Trials Photomicrographs Present Normal And Abnormal Blood Cells From A Variety Of Hematological Conditions Along With Descriptive Text--provided By Publisher. Rodents -- Rabbit -- Cat -- Dog -- Monkey -- Other Species -- Blood Collection Procedures -- Artifacts -- Bone Marrow -- Comparative Applications In Flow Cytometry. Clifford Smith And Alfred Jarecki ; Foreword By Harold Tvedten. Rev. Ed. Of: A Color Atlas Of Comparative Diagnostic And Experimental Hematology / C.a. Smith ... [et Al.]. Wolfe, 1994. Machine Generated Contents Note: Foreword.introduction.1. Rodent.2. Rabbit.3. Dog.4. Cat.5. Monkey.6. Other Species.7. Blood Collections Procedures.8. Artefacts.9. Bone Marrow.10. Methodologies.11. Flow Cytometry. Includes Bibliographical References And Index. Atlas of Comparative Diagnostic and Experimental Hematology, Second Edition 5 Contents 7 Foreword 9 Introduction 11 Dedication 13 Acknowledgments 15 1: Rodents 17 MOUSE 17 Introduction 17 Blood picture 17 Typical ranges (Siemens Advia 120) 18 HAMSTER 31 Introduction 31 Blood picture 31 GUINEA PIG 33 Introduction 33 Blood picture 33 RAT – SPRAGUE DAWLEY (SD)/HAN WISTAR (HW) 34 Introduction 34 Blood picture 34 Typical ranges (Siemens Advia 120) 35 References 52 2: Rabbit 53 Introduction 53 Blood picture 53 References 55 3: Cat 57 Introduction 57 Blood picture 57 References 60 4: Dog 61 Introduction 61 Blood picture 61 Typical ranges (Siemens Advia 120) 62 References 80 5: Monkey 81 Introduction 81 Blood picture 81 MARMOSET 82 CYNOMOLGUS 87 Introduction 87 Blood picture 87 Typical ranges (Siemens Advia 120) 88 BABOON 100 RHESUS MONKEY 102 References 103 6: Other species 105 PIG 105 Introduction 105 Blood picture 105 HORSE 107 Introduction 107 Blood picture 107 GOAT AND SHEEP 110 ASSORTED OTHER SPECIES 112 References 119 7: Blood collection procedures 121 Common bleeding sites 121 Anticoagulants 121 Staining 121 8: Artifacts 123 Collection artifacts 123 Sample transport and storage 125 Anticoagulant 126 Storage artifacts 127 Blood smear preparation 129 Stain precipitate 129 References 130 9: Bone marrow 131 Introduction 131 Review of marrow sampling techniques 131 Recommended methods for marrow sampling 132 Preparation and staining of smears 134 Evaluation 135 Interpretation 135 References 136 10: Comparative applications in flow cytometry 137 Application of flow cytometry in comparative hematology 138 References 148 Index 151 "A vital resource on blood and bone marrow cell morphology in laboratory animal medicine. This fully revised new edition is an essential reference for clinical pathologists in diagnostic laboratories, and medical or veterinary research. The atlas contains over 400 color images of cells from the peripheral blood and bone marrow from a variety of animals encountered in laboratory animal medicine, in health and disease. Key features: New chapter on flow cytometry and its application in terms of routine analyses as a means of identifying abnormalities in cell marker expression, which is of particular relevance for pre-clinical safety assessment Covers the most recent developments in laboratory animal hematology, including parameters measured by the latest generation of analyzers Coverage of a wide range of laboratory animal species, as well as those used in clinical veterinary trials Photomicrographs present normal and abnormal blood cells from a variety of hematological conditions along with descriptive text"--Résumé de l'éditeur