Assessment of Preclinical Organ Damage in Hypertension

This book presents up-to-date information on how to assess early preclinical alterations in the heart, the small and large arteries and the kidney using the most sensitive, specific and cost-effective techniques. A wide variety of techniques are discussed, with careful attention to the latest developments. For each organ, evidence is documented regarding the prevalence of organ damage in the general and the hypertensive population. Information is provided on the potential induction of regression of organ damage by treatment, the criteria for establishing significant changes and the clinical prognostic significance of regression. The manual will be invaluable for all practitioners responsible for the clinical management of hypertensive patients, given that the assessment of early preclinical cardiovascular and renal damage permits more accurate risk stratification at baseline and facilitates evaluation of cardiovascular protection when regression of structural changes is achieved during treatment. Front Matter....Pages i-viii Front Matter....Pages 1-1 Evaluation of Cardiac Damage in Hypertension: Electrocardiography....Pages 3-12 Evaluation of Cardiac Damage in Hypertension: Echocardiography....Pages 13-24 Modern Diagnostic Approach for the Assessment of Cardiac Damage in Hypertension: 3D, CT and MRI....Pages 25-37 Front Matter....Pages 39-39 Ultrasound: Carotid Intima-Media Thickness and Plaque (2D–3D)....Pages 41-50 Echocardiographic Assessment of the Aorta and Coronary Arteries in Hypertensive Patients....Pages 51-62 Pulse Wave Velocity and Central Blood Pressure....Pages 63-73 Ankle-Brachial Index (ABI)....Pages 75-79 Atherosclerosis and General Principles of Arterial Imaging....Pages 81-95 Imaging and Ageing of the Aorta and Large Arteries in the Lower Extremity....Pages 97-114 Front Matter....Pages 115-115 Micromyography....Pages 117-126 Damage of Retinal Arterioles in Hypertension....Pages 127-142 Capillaroscopy....Pages 143-149 Other Techniques for the Assessment of Small Artery Damage in Hypertension....Pages 151-156 Front Matter....Pages 157-157 Proteinuria-Microalbuminuria in Renal Damage....Pages 159-164 Glomerular Filtration Rate in Renal Damage....Pages 165-170 Other Methods to Assess Renal Damage....Pages 171-176 Front Matter....Pages 177-177 MRI/CT: Evaluation of Brain Damage in Hypertension....Pages 179-189 Questionnaires for Cognitive Function Evaluation....Pages 191-196 Other Techniques for Neurological Damage Evaluation....Pages 197-201 Front Matter....Pages 203-203 Organ Damage and Blood Pressure in Untreated and Treated Hypertensives....Pages 205-218 This Book Presents Up-to-date Information On How To Assess Early Preclinical Alterations In The Heart, The Small And Large Arteries And The Kidney In The General And The Hypertensive Population, Using The Most Sensitive, Specific And Cost-effective Techniques. A Wide Variety Of Techniques Are Discussed, With Careful Attention To The Latest Developments. For Each Organ, Evidence Is Documented Regarding The Prevalence Of Organ Damage. Information Is Provided On The Potential Induction Of Regression Of Organ Damage By Treatment, The Criteria For Establishing Significant Changes And The Clinical Prognostic Significance Of Regression. The Manual Will Be Invaluable For All Practitioners Responsible For The Clinical Management Of Hypertensive Patients, Given That The Assessment Of Early Preclinical Cardiovascular And Renal Damage Permits More Accurate Risk Stratification At Baseline And Facilitates Evaluation Of Cardiovascular Protection When Regression Of Structural Changes Is Achieved During Treatment. -- Back Cover. Part I. Heart -- Part Ii. Large Arteries -- Part Iii. Small Arteries -- Part Iv. Kidney -- Part V. Brainches Enrico Agabiti Rosei, Giuseppe Mancia, Editors. Includes Bibliographical References. Mode Of Access: World Wide Web.