ASPIRIN AND RELATED DRUGS; ED. BY K.D. RAINSFORD

Reviewing over a century of aspirin research and use, Aspirin and Related Drugs provides a comprehensive source of information on the history, chemistry, absorption in the body, therapeutic effects, toxicology, elimination, and future uses of aspirin.Highlighting the historical evolution of the salicylates and the commercial development of aspirin, the book reviews the pharmacokinetics of the salicylates, ibuprofen, and paracetamol as a basis for understanding the biodisposition of these analgesic drugs. Leading specialists discuss the therapeutic role of aspirin in the prevention and treatment of thrombo-embolic diseases, its place along with non-acetylated salicylates in the treatment of rheumatic diseases and plain, and the potential applications for aspirin and related drugs as prophylactics for colon cancer, Alzheimer's disease, and vascular dementia. They also present comparisons with other drugs used to treat pain and inflammation.With extensive data and literature covering a broad field, this is the definitive reference on the actions and applications of aspirin, salicylates, and related drugs. Physicians, pharmacists, pharmacologists, toxicologists, and chemists will find this resource useful in their daily work. It will also be valuable to pharmaceutical companies and researchers in the development of newer agents and novel applications. Reviewing Over A Century Of Aspirin Research And Use, This Book Provides A Comprehensive Source Of Information On The History, Chemistry, Absorption In The Body, Therapeutic Effects, Toxicology, Elimination, And Future Uses Of Aspirin. Highlighting The Historical Evolution Of The Salicylates And The Commercial Development Of Aspirin, It Reviews The Pharmacokinetics Of The Salicylates, Ibuprofen, And Paracetamol As A Basis For Understanding The Biodisposition Of These Analgesic Drugs. Leading Specialists Discuss The Therapeutic Role Of Aspirin In The Prevention And Treatment Of Thrombo-embolic Diseases, Its Place Along With Non-acetylated Salicylates In The Treatment Of Rheumatic Diseases And Plain, And The Potential Applications For Aspirin And Related Drugs As Prophylactics For Colon Cancer, Alzheimer's Disease, And Vascular Dementia. They Also Present Comparisons With Other Drugs Used To Treat Pain And Inflammation.with Extensive Data And Literature Covering A Broad Field, This Is The Definitive Reference On The Actions And Applications Of Aspirin, Salicylates, And Related Drugs. History And Development Of The Salicylates / K.d. Rainsford -- The Industrial History Of Analgesics: The Evolution Of Analgesics And Antipyretics / J.r. Mctavish -- Occurrence, Properties And Synthetic Developments Of The Salicylates / K.d. Rainsford -- Pharmacokinetics And Metabolism Of The Salicylates / G.g. Graham ... [et Al.] -- Metabolism And Pharmacokinetics Of Ibuprofen / G.g. Graham And K.m. Williams -- Pharmacokinetics And Metabolism Of Paracetamol (acetaminophen) / G.g. Graham And M. Hicks -- Pharmacology And Biochemistry Of Salicylates And Related Drugs / K.d. Rainsford -- Side Effects And Toxicology Of The Salicylates / K.d. Rainsford -- Reye's Syndrome And Aspirin / J.f.t. Glasgow And S.m. Hall -- Salicylates In The Treatment Of Acute Pain / K.d. Rainsford -- Acetylsalicylic Acid For The Prevention And Treatment Of Thromboembolic Diseases / K.e. Webert And J.g. Kelton -- Use Of Salicylates In Rheumatic And Related Conditions / W.w. Buchanan, W.f. Kean And K.d. Rainsford -- Aspirin And Nsaids In The Prevention Of Cancer, Alzheimer's Disease And Other Novel Therapeutic Actions / K.d. Rainsford. [edited By] K.d. Rainsford. Includes Bibliographical References And Index. Reviewing over a century of aspirin research and use, this book provides a comprehensive source of information on the history, chemistry, absorption in the body, therapeutic effects, toxicology, elimination, and future uses of aspirin. Highlighting the historical evolution of the salicylates and the commercial development of aspirin, it reviews the pharmacokinetics of the salicylates, ibuprofen, and paracetamol as a basis for understanding the biodisposition of these analgesic drugs. Leading specialists discuss the therapeutic role of aspirin in the prevention and treatment of thrombo-embolic diseases, its place along with non-acetylated salicylates in the treatment of rheumatic diseases and plain, and the potential applications for aspirin and related drugs as prophylactics for colon cancer, Alzheimer's disease, and vascular dementia. They also present comparisons with other drugs used to treat pain and inflammation. With extensive data and literature covering a broad field, this is the definitive reference on the actions and applications of aspirin, salicylates, and related drugs Reviews over a century of aspirin research and use. This work provides information on the history, chemistry, absorption in the body, therapeutic effects, toxicology, elimination, and future uses of aspirin. It includes the commercial use of aspirin and outlines the chemical properties and synthesis of aspirin and its derivatives. Critically reviews over a century of aspirin research and use including: its history, chemistry, absorption, therapeutic effects, toxicology, elimination, and future uses. It is the most definitive reference on this drug Rainsford critically reviews over a century of aspirin research and use, including it's history, chemistry, absorption in the body, therapeutic effects, toxicology, elimination and future uses