Arsenic exposure and health effects V : proceedings of the fifth International Conference on Arsenic Exposure and Health Effects, July 14-18, 2002, San Diego, California

The authoritative articles in this book represent the state-of-the-art in arsenic research. Arsenic experts from around the world - participants in the Fifth International Conference on Arsenic Exposure and Health Effects organized by the Society for Environmental Geochemistry and Health in 2002 - present their critical findings. The authors share their latest arsenic research findings in Occurrence, Epidemiology, Biomarkers and Animal Models, Mode of Action, Mode of Action, Risk Estimation, Intervention and Medical Treatment, and Water Treatment and Remediation. As in past conferences, the first report of elevated arsenic exposures in a new country was given. The Conference introduced the finding of arsenic contamination in Nepal and updates of the arsenic problems in Bangladesh, India, Vietnam are included. A vital contribution to arsenic study and policy making, this volume examines the global impact of the toxin and discusses arsenic in the environment, mechanisms of arsenic metabolism and carcinogenesis, water treatment technology, and medical care. Arsenic Exposure and Health Effects V offers informed, challenging insights into a highly important and controversial topic. Content: Preface , Pages v-vi List of Contributors , Pages xi-xx Chapter 1 - Groundwater arsenic exposure in India , Pages 3-24 , Dipankar Chakraborti, Mrinal Kumar Sengupta, Mohammad Mahmudur Rahman, Uttam Kumar Chowdhury, Dilip Lodh, Sad Ahamed, Md. Amir Hossain, Gautam Kumar Basu, Subhash Chandra Mukherjee, Kshitish Chandra Saha Chapter 2 - Groundwater arsenic contamination in Nepal: A new challenge for water supply sector , Pages 25-37 , Roshan R. Shrestha, Mathura P. Shrestha, Narayan P. Upadhyay, Riddhi Pradhan, Rosha Khadka, Arinita Maskey, Sabita Tuladhar, Binod M. Dahal, Sharmila Shrestha, Kabita B. Shrestha Chapter 3 - Environmental impacts, exposure assessment and health effects related to arsenic emissions from a coal-fired power plant in Central Slovakia; the EXPASCAN Study , Pages 39-49 , I. Thornton, M.E. Farago, T. Keegan, M.J. Nieuwenhuijsen, R.N. Colvile, B. Pesch, U. Ranft, P. Miskovic, P. Jakubis, EXPASCAN study group Chapter 4 - Trivalent arsenic species: Analysis, stability, and interaction with a protein , Pages 51-68 , Guifeng Jiang, Xiufen Lu, Zhilong Gong, William R. Cullen, X. Chris Le Chapter 5 - Arsenic in Yellowknife, North West Territories, Canada , Pages 69-78 , William R. Cullen, Elena Polishchuk, Kenneth J. Reimer, Yongmei Sun, Lixia Wang, Vivian W.-M. Lai Chapter 6 - Occurrence of public health and environmental hazards and potential remediation of arsenic-containing soils, sediments, surface water and groundwater at the Lava Cap Mine NPL Superfund site in Nevada County, California , Pages 79-91 , G. Fred Lee, Anne Jones-Lee Chapter 7 - Investigation of arsenic release from sediment minerals to water phases , Pages 93-101 , Tran Hong Con, Nguyen Thi Hanh, Pham Hung Viet, Michael Berg Chapter 8 - Arsenic and heavy metal contamination of rice, pulses and vegetables grown in Samta village, Bangladesh , Pages 103-114 , M.G.M. Alam, E.T. Snow, A. Tanaka Chapter 9 - Criteria for case definition of arsenicosis , Pages 117-133 , D.N. Guha Mazumder Chapter 10 - Arsenic exposure alters purine metabolism in rats, mice, and humans , Pages 135-145 , Luz María Del Razo, Eliud A. García-Montalvo, Olga L. Valenzuela Chapter 11 - Risk analysis of non-melanoma skin cancer incidence in arsenic exposed population , Pages 147-154 , Vladimír Bencko, Jiří Rameš, Miloslav Götzl, Petr Franěk, Marián Jakubis Chapter 12 - Effect of arsenic-contaminated drinking water on skin cancer prevalence in Wisconsin's Fox River Valley , Pages 155-163 , Lynda Knobeloch, Henry Anderson Chapter 13 - Alteration of GSH level, gene expression and cell transformation in NIH3T3 cells by chronic exposure to low dose of arsenic , Pages 167-179 , Yu Hu, Ximei Jin, Guoquan Wang, Elizabeth T. Snow Chapter 14 - Laboratory and field evaluation of potential arsenic exposure from mine tailings to grazing cattle , Pages 181-195 , Jack C. Ng, Scott L. Bruce, Barry N. Noller Chapter 15 - Does arsenic require a carcinogenic partner? , Pages 197-209 , Toby G. Rossman, Ahmed N. Uddin, Fredric J. Burns, Maarten C. Bosland Chapter 16 - Carcinogenicity of dimethylarsinic acid and relevant mechanisms , Pages 211-222 , Min Wei, Hideki Wanibuchi, Keiichirou Morimura, Shoji Fukushima Chapter 17 - Enzymology and toxicity of inorganic arsenic , Pages 225-240 , H. Vasken Aposhian, Robert A. Zakharyan, Sheila M. Healy, Eric Wildfang, Jay S. Petrick, Adriana Sampayo-Reyes, Philip G. Board, Dean E. Carter, D.N. Guha Mazumder, Mary M. Aposhian Chapter 18 - Structural proteomics of arsenic transport and detoxification , Pages 241-253 , Zijuan Liu, Rita Mukhopadhyay, Jin Shi, Jun Ye, Barry P. Rosen Chapter 19 - A novel S -adenosylmethionine-dependent methyltransferase from rat liver cytosol catalyzes the formation of methylated arsenicals , Pages 255-266 , Stephen B. Waters, Shan Lin, Miroslav Styblo, David J. Thomas Chapter 20 - Metabolism of arsenic and gene transcription regulation: Mechanism of AP-1 activation by methylated trivalent arsenicals , Pages 267-281 , Zuzana Drobná, Ilona Jaspers, Miroslav Stýblo Chapter 21 - Effect of antioxidants on the papilloma response and liver glutathione modulation mediated by arsenic in Tg.AC transgenic mice , Pages 283-293 , K. Trouba, A. Nyska, M. Styblo, D. Dunson, L. Lomnitski, S. Grossman, G. Moser, A. Suttie, R. Patterson, F. Walton, D. Germolec Chapter 22 - Application of filter arrays to the study of arsenic toxicity and carcinogenesis , Pages 295-303 , Jie Liu, Hua Chen, Maria Kadiiska, Yaxiong Xie, Michael P. Waalkes Chapter 23 - Regulation of redox and DNA repair genes by arsenic: Low dose protection against oxidative stress? , Pages 305-319 , Elizabeth T. Snow, Yu Hu, Catherine B. Klein, Kate L. McCluskey, Michael Schuliga, Peter Sykora Chapter 24 - Carcinogenicity of dimethylarsinic acid (DMA V ) , Pages 321-335 , Samuel M. Cohen, Chris Le, Xiufen Lu, Marty Cano, Lora L. Arnold Chapter 25 - Urinary speciation of sodium arsenate in folate receptor knockout mice , Pages 337-344 , Ofer Spiegelstein, Xiufen Lu, X. Chris Le, Richard H. Finnell Chapter 26 - Some chemical properties underlying arsenic's biological activity , Pages 345-354 , Kirk T. Kitchin, Kathleen Wallace, Paul Andrewes Chapter 27 - Arsenic metabolism in hyperbilirubinemic rats: Distribution and excretion in relation to transformation , Pages 355-367 , Kazuo T. Suzuki, Takayuki Tomita, Yasumitsu Ogra, Masayoshi Ohmichi Chapter 28 - Incorporating mechanistic insights in a PBPK model for arsenic , Pages 369-377 , Elaina M. Kenyon, Michael F. Hughes, Marina V. Evans, Miroslav Styblo, Luz Maria Del Razo, Michael Easterling Chapter 29 - Natural history following arsenic exposure: A study in an arsenic endemic area of West Bengal, India , Pages 381-389 , D.N. Guha Mazumder, Nilima Ghose, Kunal Mazumder, Amal Santra, Sarbari Lahiri, Subhankar Das, Arindam Basu, Allan H. Smith Chapter 30 - Saha's grading of arsenicosis progression and treatment , Pages 391-414 , Kshitish C. Saha Chapter 31 - Painting tube wells red or green alone does not help arsenicosis patients , Pages 415-419 , Quazi Quamruzzaman, Mahmuder Rahman, M.A. Salam, A.I. Joarder, M. Shahjahan, S.U. Mollah Chapter 32 - Arsenic mitigation in Bangladesh: Progress of the UNICEF-DPHE Arsenic Mitigation Project 2002 , Pages 421-437 , Colin Davis Chapter 33 - Normative role of WHO in mitigating health impacts of chronic arsenic exposure in the South-east Asia region , Pages 439-447 , Deoraj Caussy Chapter 34 - “Arsenic Solutions” Web platform of >50 options for developing countries: Collaborative design and innovation for the common good , Pages 451-458 , Susan Murcott Chapter 35 - Investigation of arsenic removal technologies for drinking water in Vietnam , Pages 459-469 , Pham Hung Viet, Tran Hong Con, Cao The Ha, Hoang Van Ha, Michael Berg, Walter Giger, Roland Schertenleib Chapter 36 - Removing arsenic from drinking water: A brief review of some lessons learned and gaps arisen in Chilean water utilities , Pages 471-481 , Ana María Sancha Chapter 37 - Disposal of wastes resulting from arsenic removal processes , Pages 483-489 , Michael J. MacPhee, John T. Novak, David A. Cornwell, Rodney N. Mutter Chapter 38 - Development of a low-waste technology for arsenic removal from drinking water , Pages 491-501 , József Hlavay, Klára Polyák, János Molnár, Kornél Gruber, Pál Medgyesi, Márta Hódi Chapter 39 - An update on some arsenic programs at the US EPA , Pages 505-519 , Charles O. Abernathy, Mike Beringer, R.L. Calderon, T. McMahon, E. Winchester Subject index , Pages 521-533