Anticancer plants : Properties and Application. Volume 1 / edited by Mohd Sayeed Akhtar, Mallappa Kumara Swamy

Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types. The anticancer plants such as __Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata__, __Crateva nurvala__, __Croton tonkinensis__, __Oplopanax horridus__ etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities. __Anticancer plants: Volume 1, Properties and Application__ is a very timely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners. Front Matter ....Pages i-xx Current Practices and Awareness of Anticancer Plants in the Traditional Healthcare System (Paola De Cicco, Elisabetta Panza, Chiara Armogida, Giuseppe Ercolano, Giuseppe Cirino, Angela Ianaro)....Pages 1-36 Phytochemical and Biological Properties of Lippia gracilis (Valéria Regina de Souza Moraes, Paulo Cesar de Lima Nogueira, Emmanoel Vilaça Costa, Luciano de Souza Santos, Valdenizia Rodrigues Silva, Larissa Mendes Bomfim et al.)....Pages 37-55 Use of Indian Indigenous Fruits in Cancer Prevention and Treatment (Manjeshwar Shrinath Baliga, Suresh Rao, Pratima Rao, Krishnaprasad, Sanath Kumar Hegde, Kandel Codi Jalaluddin Akbar et al.)....Pages 57-76 Potentiality of Anticancer Plant-Derived Compounds of North-East India (Mohan Lal, Nibir Ranjan Parasar, Anil Kumar Singh, Mohd Sayeed Akhtar)....Pages 77-89 Plant-Derived Compounds in Cancer Therapy: Traditions of Past and Drugs of Future (Bee Ling Tan, Mohd Esa Norhaizan)....Pages 91-127 Anticancer Plant Molecules for the Improvement of Immune System (Om Prakash, Pratibha Preeti Maurya, Ajeet)....Pages 129-140 Fermented Food-Derived Bioactive Compounds with Anticarcinogenic Properties: Fermented Royal Jelly As a Novel Source for Compounds with Health Benefits (Muhammad Hussein Alu’datt, Taha Rababah, Hafiz Arbab Sakandar, Muhammad Imran, Neveen Mustafa, Mohammad Noor Alhamad et al.)....Pages 141-165 Mass Spectrometry-Based Techniques for the Assessment of Pharmacological Responses of Ayurvedic Drugs (Amey Shirolkar, Manasi Malgaonkar, Amit Pawase, Sudesh Gaidhani, Sharad Pawar)....Pages 167-193 Assessment of Anticancer Properties of Betelvine (Deepali Shukla, Jayendra Johri, Suchi Srivastava, Poonam C. Singh)....Pages 195-206 Analysis of Patents Filed for the Herbal Therapeutics Against Cancer (Pooja Rawat, Pawan Kumar Singh)....Pages 207-228 Appraisal of Medicinal Plants with Anticancer Properties in South America (Alírica Isabel Suárez, Katiuska Chávez)....Pages 229-283 Scientific Validation of the Usefulness of Withania somnifera Dunal in the Prevention and Treatment of Cancer (G. S. Pavan Kumar Achar, B. T. Prabhakar, Suresh Rao, Thomas George, Soniya Abraham, Nicole Sequeira et al.)....Pages 285-301 Anticancer Potential of Mangrove Plants: Neglected Plant Species of the Marine Ecosystem (Rout George Kerry, Pratima Pradhan, Gitishree Das, Sushanto Gouda, Mallappa Kumara Swamy, Jayanta Kumar Patra)....Pages 303-325 Piper betle Linn. in Cancer: Past, Present, and Future (Avinash Kundadka Kudva, Suresh Rao, Pratima Rao, Romith Periera, Ganesh Bhandari, Jaffey M. Mathew et al.)....Pages 327-347 Anticancer Properties of Curcumin and Its Efficacy for Treating Central Nervous System Neoplasms (Neil V. Klinger, Sandeep Mittal)....Pages 349-366 Vitamin E: Nature’s Gift to Fight Cancer (Siti Syairah Mohd Mutalip)....Pages 367-393 Use of Plant Secondary Metabolites as Nutraceuticals for Treatment and Management of Cancer: Approaches and Challenges (Zahid H. Siddiqui, B. Hareramdas, Zahid K. Abbas, Talat Parween, Mohammad Nasir Khan)....Pages 395-413 Usefulness of Ocimum sanctum Linn. in Cancer Prevention: An Update (Naveen Kaushal, Suresh Rao, Preety Ghanghas, Soniya Abraham, Thomas George, Sueallen D’souza et al.)....Pages 415-429 Phytochemicals with Anticancer Potential: Methods of Extraction, Basic Structure, and Chemotherapeutic Action (Gulrez Nizami, R. Z. Sayyed)....Pages 431-453 Anticancer Plants and Their Conservation Strategies: An Update (Vankayalapati Vijaya Kumar, Mallappa Kumara Swamy, Mohd. Sayeed Akhtar)....Pages 455-483 Anticancer Plants: Chemistry, Pharmacology, and Potential Applications (V. D. Ravichandra, C. Ramesh, Mallappa Kumara Swamy, B. Purushotham, Gudepalya Renukaiah Rudramurthy)....Pages 485-515 Botany, Chemistry, and Pharmaceutical Significance of Sida cordifolia: A Traditional Medicinal Plant (Hassan Ahmed, Abdul Shukor Juraimi, Mallappa Kumara Swamy, Muhammad Saiful Ahmad-Hamdani, Dzolkifli Omar, Mohd Yusop Rafii et al.)....Pages 517-537 Anticancer Properties of Natural Compounds on Prostate Cancer ( Priyadarshini, Abhishek Negi)....Pages 539-558 Phytochemicals Against Cancer Stem Cells (Kok Hoong Leong, Kin Weng Kong, Lip Yong Chung)....Pages 559-582 Cancer is one of the leading death cause of human population increasingly seen in recent times. Plants have been used for medicinal purposes since immemorial times. Though, several synthetic medicines are useful in treating cancer, they are inefficient and unsafe. However, plants have proved to be useful in cancer cure. Moreover, natural compounds from plants and their derivatives are safe and effective in treatment and management of several cancer types. The anticancer plants such as Catharanthus roseus, Podophyllum peltatum, Taxus brevifolia, Camptotheca acuminate, Andrographis paniculata, Crateva nurvala, Croton tonkinensis, Oplopanax horridus etc., are important source of chemotherapeutic compounds. These plants have proven their significance in the treatment of cancer and various other infectious diseases. Nowadays, several well-known anticancer compounds such as taxol, podophyllotoxins, camptothecin, vinblastine, vincristine, homoharringtonine etc. have been isolated and purified from these medicinal plants. Many of them are used effectively to combat cancer and other related diseases. The herbal medicine and their products are the most suitable and safe to be used as an alternative medicine. Based on their traditional uses and experimental evidences, the anticancer products or compounds are isolated or extracted from the medicinally important plants. Many of these anticancer plants have become endangered due to ruthless harvesting in nature. Hence, there is a need to conserve these species and to propagate them in large scale using plant tissue culture. Alternatively, plant cell tissue and organ culture biotechnology can be adopted to produce these anticancer compounds without cultivation. The proper knowledge and exploration of these isolated molecules or products could provide an alternative source to reduce cancer risk, anti-tumorigenic properties, and suppression of carcinogen activities. Anticancer plants: Volume 1, Properties and Application is a very t imely effort in this direction. Discussing the various types of anticancer plants as a source of curative agent, their pharmacological and neutraceutical properties, cryo-preservations and recent trends to understand the basic cause and consequences involved in the diseases diagnosis. We acknowledge the publisher, Springer for their continuous inspiration and valuable suggestions to improvise the content of this book. We further extend our heartfelt gratitude to all our book contributors for their support, and assistance to complete this assignment. I am sure that these books will benefit the scientific communities including academics, pharmaceuticals, nutraceuticals and medical practitioners