Annual reports in medicinal chemistry ; sponsored by the Division of Medicinal Chemistry of the American Chemical Society. Vol. 7

Content: Contributors Page ii Edited by Page iii Copyright page Page iv Preface Page ix Richard V. Heinzelman Inhibitors of Folate Biosynthesis and Utilization – Evolutionary Changes as a Basis for Chemotherapy Original Research Article Pages 1-5 George H. Hitchings Chapter 1. Antipsychotic and Anti-anxiety Agents Original Research Article Pages 6-17 Charles L. Zirkle, Carl Kaiser Chapter 2. Antidepressives and Stimulants Original Research Article Pages 18-30 Carl Kaiser, Charles L. Zirkle Chapter 3. Analgesics and Narcotic Antagonists Original Research Article Pages 31-38 Franklin M. Robinson Chapter 4. Sedatives, Hypnotics, Anticonvulsants and General Anesthetics Original Research Article Pages 39-46 A.D. Rudzik, W. Friis Chapter 5. Recent Developments Relating Serotonin and Behavior Original Research Article Pages 47-58 Albert Weissman, Charles A. Harbert Chapter 5. Antihypertensive Agents Original Research Article Pages 59-68 Anthony M. Roe Chapter 7. Antianginal Agents Original Research Article Pages 69-77 Charles F. Schwender Chapter 8. Antithrombotic Agents Original Research Article Pages 78-88 Leonard J. Czuba Chapter 9. Pulmonary and Antiallergy Agents Original Research Article Pages 89-98 S. Tozzi Chapter 10. Antibiotics Original Research Article Pages 99-108 Frank C. Sciavolino Chapter 11. Antifungal Agents Original Research Article Pages 109-118 J. Allan Waitz, C.G. Drube Chapter 12. Antiviral Agents Original Research Article Pages 119-128 Timothy H. Cronin Chapter 13. Antineoplastic Agents Original Research Article Pages 129-144 C.C. Cheng Chapter 14. Antiparasitic Agents Original Research Article Pages 145-156 M. Hoffer, A.I. Rachlin Chapter 15. Prostaglandins and Related Compounds Original Research Article Pages 157-168 Gordon L. Bundy Chapter 16. Atherosclerosis Original Research Article Pages 169-181 Thomas R. Blohm Chapter 17. Steroids and Biologically Related Compounds Original Research Article Pages 182-193 Duane F. Morrow, Duane Gallo Chapter 18. Peptide Hormones of the Hypothalamus and Pituitary. Original Research Article Pages 194-207 Roger Burgus Chapter 19. Non-steroidal Antiinflammatory Agents Original Research Article Pages 208-216 Peter F. Juby, Thomas W. Hudyma Chapter 20. Mechanisms of Resistance to Antibiotics Original Research Article Pages 217-227 Julian Davies Chapter 21. The Serum Complement System Original Research Article Pages 228-237 Harvey R. Colten Chapter 22. Immediate Hypersensitivity: Laboratory Models and Experimental Findings Original Research Article Pages 238-248 Michael K. Bach Chapter 23. Transition State Analogs as Enzyme Inhibitors Original Research Article Pages 249-258 G.E. Lienhard Chapter 24. Biopharmaceutics and Pharmacokinetics Original Research Article Pages 259-268 Leslie Z. Benet Chapter 25. Reactions of Interest in Medicinal Chemistry Original Research Article Pages 269-278 Herbert T. Nagasawa, John A. Thompson Chapter 26. Intramolecular Catalysis in Medicinal Chemistry Original Research Article Pages 279-288 Richard D. Gandour, Richard L. Schowen Chapter 27. Peptide Synthesis Original Research Article Pages 289-295 John Morrow Stewart Chapter 28. Preparation of Radioisotope-Labeled Drugs Original Research Article Pages 296-306 Richard C. Thomas Compound Name and Code Number Index Pages 307-316