Animal Welfare in a Pandemic: What Does COVID-19 Tell us for the Future?

A consummate classic with a fresh approach to pediatric dermatology Children ́s skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions - both common and rare - with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data - especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper's Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world. Cover Half Title Series Page Title Page Copyright Page Dedication Table of Contents Authors Preface Acknowledgements Chapter 1 The coronavirus disease 2019 (COVID-19) pandemic 1.1 Introduction 1.2 COVID-19 pandemic and the virus that caused it 1.3 The origin of the SARS-CoV-2 1.4 Effects of SARS-CoV-2 on the human population 1.5 Why it is important to incorporate animals into the discussion: One Health/One Welfare/One Medicine 1.6 Conclusions Notes Chapter 2 Can the susceptibility of animals to SARS-CoV-2 be predicted? 2.1 Introduction 2.2 A quick crash course in molecular biology 2.3 Can molecular biology help? 2.4 Which animals are predicted to be infected with SARS-CoV-2? 2.5 What data are missing? 2.6 How can analysis using in silico techniques be improved to aid in future predictions? 2.7 Conclusions Notes Chapter 3 Animals that were infected in the real world 3.1 Introduction 3.2 Animals that were infected 3.3 What was not known 3.4 How risk, uncertainty, and ambiguity were handled 3.5 How can transmission of the virus in animals be better tracked and real-time evidence made publicly and globally available? 3.6 Non-mammals and COVID-19 3.7 Conclusions Notes Chapter 4 Animal vaccines 4.1 Introduction 4.2 Vaccines developed in animals 4.3 Should animals be vaccinated when human populations are not? 4.4 Use of laboratory animal models 4.5 Vaccines of the future, will this transform their use in animals? 4.6 Conclusions Notes Chapter 5 Animal conservation and the pandemic 5.1 Introduction 5.2 The impact of the pandemic on animal conservation and zoos, wildlife parks, and aquaria 5.3 The impact on animals in the wild 5.4 Conclusions Notes Chapter 6 The indirecteffects of COVID-19on animals 6.1 Introduction 6.2 Human perception of animals as transmitters 6.3 Euthanasia/culling programmes that took place around the world 6.4 Animal behaviour, moving into populated areas (analogies to Chernobyl exclusion zone) 6.5 PPE being abandoned and the issues it causes 6.6 Massive use of cleaning/disinfectant materials, etc. and impact on the environment 6.7 The effect on companion animals,including dogs, cats, and rodents 6.8 Conclusions Notes Chapter 7 Animals,pandemics, andthe future 7.1 Introduction 7.2 Long COVID – what we know: a concern for animals? 7.3 What can be learnt from COVID-19 for the next epidemic/pandemic 7.4 Sources of future viruses and their transmission, the role of animals and of human interactions with animals 7.5 How to mitigate effects on conservation and use of PPE 7.6 Ethics considerations when considering SARS-CoV-2 and animals 7.7 One World/One Health/One Medicine 7.8 Plants and ecosystems 7.9 Conclusions Notes Chapter 8 Final thoughts Index "A consummate classic with a fresh approach to pediatric dermatology Children's skin is different. Maturation affects the epidermal barrier, the cutaneous microbiome, adnexal structures, vasculature, and transcutaneous absorption of drugs. The immature skin is more susceptible to pathogens and environmental disruption. Many genetic disorders are either present at birth or manifest early in childhood. Skin diseases thus present differently in children than in adults. Pediatric dermatology has seen significant advances over the last decade, particularly in the field of molecular genetics research, which has furthered our understanding of the pathogenesis of many skin diseases and the development of new approaches to treatment. This fourth edition of the Harper classic provides state-of-the-art information on all aspects of skin disease in children. It covers the diagnosis and treatment of all conditions ? both common and rare ? with a consistently evidence-based approach. Existing content has been refreshed and fully updated to reflect emerging thinking and to incorporate the latest in research and clinical data ? especially at the genetic level. This new fourth edition includes: Greater focus on the genetics behind skin disease, including new genes/genodermatoses, progress in genetic analysis, and stem cell transplants Increased coverage of lasers and other technologies used to treat skin disease More summary tables, learning points, tables of differential diagnosis, and clinical algorithms for diagnosis and management Additional online features, including patient information links and multiple choice questions Harper?s Textbook of Pediatric Dermatology delivers crucial clinical insights and up-to-date research information that spans the breadth of the field. As the most comprehensive reference book on this subject available, this revised fourth edition will support and guide the daily practice of both dermatologists and pediatricians across the world"-- Provided by publisher This book explores the impact of COVID-19 on a wide array of animals, from those in the wild to companion and captive animals. It contributea to a genuinely One Health approach where the health and welfare of both humans and animals are considered holist